Green synthesis of Ag–Fe bimetallic nanoparticles using fungal filtrates: unlocking multifunctional medical and environmental applications DOI Creative Commons
Bhakti K. Patel, Nisha Choudhary, Dushyant R. Dudhagara

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(3), P. 1565 - 1575

Published: Jan. 1, 2025

The current investigation focuses on synthesizing Ag-Fe bimetallic nanoparticles (AgFe-BMNPs) using cell-free filtrates of the Gymnascella dankaliensis as a novel fungal reducing agent. optical, morphological, and surface properties these fungus-fabricated AgFe-BMNPs their monometallic counterparts (AgNPs FeNPs) were analyzed sophisticated nanotechnology instruments. UV-visible spectrum showed peaks at 231 nm 415 for BMNPs 450 386 AgNPs FeNPs, respectively. XRD diffractograms revealed crystallographic 32.96°, 35.32°, 49.32° with crystalline size 10.68 nm. FTIR indicates 954 cm-1 (M-O bond) 599 (M-C\M-L bond). Agglomerated, spherical mean 96.76 spotted in SEM micrographs. tested anticancer antibacterial activities, dye removal efficiency, seed germination enhancement. study found that hold promising potential application breast cancer therapy 1 μg mL-1 IC50 value. It also exhibited potent activity 50 concentration against Bacillus cereus,Serratia marcescens, megaterium, Staphylococcus aureus. A comparative batch adsorption methylene blue over 180 min capabilities 89% BMNPs. Different concentrations (0.02, 0.04, 0.08 mg mL-1) demonstrated superior efficiency up to 90% enhanced 6 h mark 91.87% water retention capacity Vigna radiata. This research underscores medical, environmental, agricultural AgFe-BMNPs, highlighting multifaceted benefits nanotechnology.

Language: Английский

Gum Arabic assisted the biomass synthesis of bimetallic silver copper oxide nanoparticles using gamma-rays for improving bacterial and viral wound healing: Promising antimicrobial activity against foot and mouth disease DOI
Ahmed I. El‐Batal, M. Eisa,

Mohamed A.M. Saad

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 262, P. 130010 - 130010

Published: Feb. 8, 2024

Language: Английский

Citations

10
In Vivo and in Vitro activity of colistin-conjugated bimetallic silver-copper oxide nanoparticles against Pandrug-resistant Pseudomonas aeruginosa DOI Creative Commons

Asmaa Abdul Hak,

Hamdallah Zedan, Hadir A. El‐Mahallawy

et al.

BMC Microbiology, Journal Year: 2024, Volume and Issue: 24(1)

Published: June 17, 2024

Abstract Background Addressing microbial resistance urgently calls for alternative treatment options. This study investigates the impact of a bimetallic formulation containing colistin, silver, and copper oxide on pandrug-resistant, highly virulent Pseudomonas aeruginosa (P. aeruginosa) isolate from cancer patient at National Cancer Institute, Cairo University, Egypt. Methods Silver nanoparticles (Ag NPs), (CuO silver-copper (Ag-CuO NPs) were synthesized using gamma rays, combined with colistin (Col), characterized by various analytical methods. The antimicrobial activity Col-Ag NPs, Col-CuO Col-Ag-CuO NPs against P. was evaluated agar well diffusion method, their minimum inhibitory concentration (MIC) determined broth microdilution. Virulence factors such as pyocyanin production, swarming motility, biofilm formation assessed before after NPs. in vivo efficacy Galleria mellonella model, antibacterial mechanism examined through membrane leakage assay. Results optimal synthesis Ag occurred ray dose 15.0 kGy, highest optical density (OD) 2.4 375 nm. Similarly, CuO had an OD 1.5 330 Bimetallic Ag-CuO most potent yielding 1.9 425 MIC significantly reduced when nanoparticles: 8 µg/mL alone, 0.046 0.0117 four-fold compared to Increasing sub-inhibitory 0.29 × 10 -2 0.58 32–64% twitching motility 34–97%. At these concentrations, production decreased 39–58%, inhibited 33–48%. non-toxic , showing 100% survival day 3, similar saline-treated group. Conclusions conjugated presents promising combating challenging pathogen hospital settings. Further research is needed explore elucidate mechanisms underlying effects colistin-bimetallic persistence dissemination.

Language: Английский

Citations

9
Enhancement of Antibacterial, Anti-angiogenic and Anticancer Properties of Biosynthesized Zinc Oxide with Bioderived Mesoporous Carbon DOI
Alfredi A. Moyo,

Sneha R. Bhosale,

P.S. Patil

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: 1328, P. 141344 - 141344

Published: Jan. 5, 2025

Language: Английский

Citations

1
Sustainable approach for fabrication of pineapple agro-waste mediated cellulose nanocrystals embedded with Ag/Ag2O/ZnO nanocomposites for efficient removal of waterborne pathogens in wastewater DOI
Samudrika Aththanayaka, Gobika Thiripuranathar, Sagarika Ekanayake

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 310, P. 143272 - 143272

Published: April 18, 2025

Language: Английский

Citations

1
Biogenic nanoparticles from waste fruit peels: Synthesis, applications, challenges and future perspectives DOI

Priya,

Sumel Ashique, Obaid Afzal

et al.

International Journal of Pharmaceutics, Journal Year: 2023, Volume and Issue: 643, P. 123223 - 123223

Published: July 11, 2023

Language: Английский

Citations

22
Amomum subulatum Fruit Extract Mediated Green Synthesis of Silver and Copper Oxide Nanoparticles: Synthesis, Characterization, Antibacterial and Anticancer Activities DOI Open Access

Sarika Dhir,

Rohit Dutt, Rahul Pratap Singh

et al.

Processes, Journal Year: 2023, Volume and Issue: 11(9), P. 2698 - 2698

Published: Sept. 9, 2023

This research presents a straightforward, effective, and eco-friendly method for the production of silver nanoparticles (AgNPs) copper oxide (CuONPs) using dried fruit Amomum subulatum as reducing, stabilizing, capping agent. The formation AgNPs CuONPs is supported by presence surface plasmon resonance band (SPR) at 440 nm 245 CuONPs. Additionally, identification specific biomolecules responsible synthesis was confirmed through FTIR spectra analysis. Transmission electron microscope (TEM) images demonstrated that had spherical shapes, with mean particle diameters 20.6 24.7 nm, respectively. X-ray diffraction selected area (SAED) analyses provided evidence crystalline nature synthesized elements observed energy-dispersive spectroscopy (EDS) Furthermore, antibacterial activity found to be superior against human pathogens such Escherichia coli, Staphylococcus aureus, Bacillus subtilis. cytotoxic biosynthesized (NPs) evaluated in vitro cervical cells (HeLa) breast (MCF-7). In MCF-7 cells, IC50 value estimated 39.79 µg/mL, while 83.89 µg/mL. HeLa 45.5 CuONPs, it 97.07 For first time, an from extract has been discussed along their comparative evaluation study. These results highlight promising applications effective agents microbial infections potential candidates cancer therapy.

Language: Английский

Citations

17
Watermelon Rind Mediated Biosynthesis of Bimetallic Selenium-Silver Nanoparticles: Characterization, Antimicrobial and Anticancer Activities DOI Creative Commons
Amr H. Hashem, Gharieb S. El‐Sayyad, Abdulaziz A. Al–Askar

et al.

Plants, Journal Year: 2023, Volume and Issue: 12(18), P. 3288 - 3288

Published: Sept. 17, 2023

One of the most hazardous diseases that influences human health globally is microbial infection. Therefore, bimetallic nanoparticles have received much attention for controlling infections in current decade. In present study, selenium–silver (Se-Ag NPs) were effectively biosynthesized using watermelon rind WR extract through green technique first time. UV-visible spectroscopy, transmission electron microscopy (TEM), and energy dispersive X-ray spectroscopy (EDX) methods used to characterize produced NPs. The results indicated Se-Ag NPs had synergistic antimicrobial activity at low concentrations, which helped reduce toxicity Ag after preparation increase their great potential. with sizes ranging from 18.3 nm 49.6 detected by TEM. NP surfaces uniformly visible SEM picture. cytotoxicity was assessed against Wi38 normal cell line check safety, where IC50 168.42 µg/mL. showed antibacterial action Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Klebsiella oxytoca, Bacillus subtilis, Staphylococcus aureus a minimum inhibitory concentration (MIC) 12.5 50 Additionally, promising anticancer toward MCF7 cancerous line, 21.6 conclusion, time extract, strong antibacterial, antifungal properties.

Language: Английский

Citations

17
Phyto-mediated synthesis of Ag, ZnO, and Ag/ZnO nanoparticles from leave extract of Solanum macrocarpon: Evaluation of their antioxidant and anticancer activities DOI Creative Commons
Marwa Yousry A. Mohamed, Hela Ferjani, Oluwasayo E. Ogunjinmi

et al.

Inorganica Chimica Acta, Journal Year: 2024, Volume and Issue: 569, P. 122086 - 122086

Published: April 24, 2024

Language: Английский

Citations

9
Green biosynthesis of bimetallic selenium–gold nanoparticles using Pluchea indica leaves and their biological applications DOI Creative Commons
Ahmed Mohamed Aly Khalil, Ebrahim Saied, Alsayed E. Mekky

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 11

Published: Jan. 11, 2024

Increasing bacterial resistance and the negative impact of currently used antibacterial agents have produced need for novel anticancer drugs. In this regard, nanotechnology could provide safer more efficient therapeutic agents. The main methods nanoparticle production are chemical physical approaches that often costly environmentally unsafe. current study, Pluchea indica leaf extract was biosynthesis bimetallic selenium–gold nanoparticles (Se-Au BNPs) first time. Phytochemical examinations revealed P. includes 90.25 mg/g dry weight (DW) phenolics, 275.53 DW flavonoids, 26.45 tannins. X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier-transform infrared (FTIR) spectroscopy, dynamic light scattering (DLS), scanning (SEM), energy-dispersive spectroscopy (EDX) techniques were employed to characterize Se-Au BNPs. Based on UV-vis spectra, absorbance BNPs peaked at 238 374 nm. SEM imaging, emerged as bright particles, both Au Se uniformly distributed throughout extract. XRD analysis average size 45.97 showed properties against Escherichia coli , Pseudomonas aeruginosa Staphylococcus aureus Bacillus subtilis with minimum inhibitory concentrations (MICs) 31.25, 15.62, 3.9 μg/mL, respectively. Surprisingly, a cytotoxicity assay IC 50 value toward Wi 38 normal cell line 116.8 implying all MICs described above be safely. More importantly, shown higher efficacy human breast cancer cells (MCF7), an 13.77 μg/mL. conclusion, paper is data effective utilization in biologically active

Language: Английский

Citations

7
Amine-functionalized mesoporous silica nanoparticles decorated by silver nanoparticles for delivery of doxorubicin in breast and cervical cancer cells DOI Creative Commons

Melika Ghobadi,

Saeideh Salehi,

Mohammad Taha Salmanifard Ardestani

et al.

European Journal of Pharmaceutics and Biopharmaceutics, Journal Year: 2024, Volume and Issue: 201, P. 114349 - 114349

Published: June 5, 2024

Nanocarriers have demonstrated promising potential in the delivery of various anticancer drugs and improving efficiency treatment. In this study, silver nanoparticles (AgNPs) were green-synthesized using extracts different parts pomegranate plant, including peel, flower petals, calyx. To obtain most efficient extract used for green synthesis AgNPs, all three types synthesized characterized. Then, (3-Aminopropyl) triethoxysilane-functionalized mesoporous silica (MSNs-APTES) decorated with AgNPs fabricated via a one-pot green-synthesis method. directly coated on surface MSNs-APTES by adding enriched source reducing agent leading to converting ion AgNPs. The MSN-APTES-AgNPs (MSNs-AgNPs) been thoroughly characterized nanoparticle characterization techniques. addition, DNA cleavage hemolysis activities analyzed, confirming biocompatibility nanoparticles. Doxorubicin (DOX, as breast/cervical anti-cancer drug) loading (42.8%) release profiles investigated UV–visible spectroscopy. fibroblast, breast cancer, cervical cancer cells' viability against DOX-loaded also studied. results high drug loading, uniform shape, small functionalized its great management.

Language: Английский

Citations

6