Association between bedtime and female infertility: a secondary analysis from a cross-sectional study DOI Creative Commons
Hanzhi Zhang, Jun Zhang, Wenxiu Chen

et al.

Frontiers in Endocrinology, Journal Year: 2024, Volume and Issue: 15

Published: June 20, 2024

Objective To evaluate the association between bedtime and infertility to identify optimal for women of reproductive age. Methods We conducted a cross-sectional study using data from 3,903 female participants in National Health Nutrition Examination Survey (NHANES) 2015 2020. The effect on was assessed binary logistic regression different models, including crude model adjusted models. non-linear correlation infertility, generalized additive models (GAM) were utilized. Subgroup analyses by age, body mass index (BMI), waist circumference, physical activity total time, marital status, smoking drinking status sleep duration. Results After adjusting potential confounders (age, race, duration, education, BMI, time), relationship observed with inflection point at 22:45. left side point, no significant detected. However, right it, positively related (OR: 1.22; 95% CI: 1.06 1.39; P = 0.0049). showed that late sleepers higher BMI more prone than those lower (BMI: 25–30 kg/m 2 : OR: 1.26; 1.51; 0.0136; ≥ 30 kg/m²: 1.21, 1.09 1.34; 0.0014). Conclusion Bedtime non-linearly associated which may provide guidance behavior childbearing

Language: Английский

Composite dietary antioxidant index associated with delayed biological aging: a population-based study DOI Creative Commons
Huiqin He, Xin Chen, Yiming Ding

et al.

Aging, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 2, 2024

Objective: The objective of this study was to explore the potential correlation between composite dietary antioxidant index (CDAI) and biological aging, addressing insufficient epidemiological evidence in area. Methods: Participants meeting eligibility criteria were selected from National Health Nutrition Examination Surveys (NHANES) conducted 2001 2018. CDAI determined based on antioxidants obtained 24-hour recalls. Biological age using PhenoAge algorithms incorporating various clinical features. Weighted multiple models employed investigate assess association age. Results: Analysis quartile revealed disparities terms age, gender, ethnicity, educational level, marital status, poverty, calories intakes, smoking, drinking BMI, physical activity, PhenoAge. After adjusting for confounding factors, a significant inverse relationship found Phenotypic Age, with each standard deviation increase score correlating 0.18-year decrease Age. These negative correlations advancement observed regardless activity smoking body mass index. Conclusions: Our findings demonstrate positive higher scores delayed aging. results have implications public health initiatives aimed at promoting healthy aging through interventions.

Language: Английский

Citations

34
Associations between weight-adjusted waist index and bone mineral density: results of a nationwide survey DOI Creative Commons
Ya Zhang,

Haiyang Wu,

Cheng Li

et al.

BMC Endocrine Disorders, Journal Year: 2023, Volume and Issue: 23(1)

Published: Aug. 3, 2023

Abstract Background The weight-adjusted waist circumference index (WWI) is a novel obesity indicator that offers improved accuracy in assessing both muscle and fat mass compared to traditional measures. This study aimed investigate the association between WWI bone mineral density (BMD) adults. Methods Weighted multivariate logistic regression, subgroup analysis, interaction tests restricted cubic spline (RCS) curves were used explore relationship BMD based on data from National Health Nutrition Examination Survey (NHANES). Results had 40,568 individuals total. At all four measurement sites, we detected negative linear correlation BMD. Even when quartile factors for created, this unfavorable connection maintained. In comparison those lowest quartile, highest percentile of showed declines lumbar 0.08 g/cm 2 femoral neck 0.03 , respectively. adverse correlation, nevertheless, differed among several categories. Conclusions Our findings suggest an US Employing as tool osteoporosis prevention general population may enhance interventions.

Language: Английский

Citations

31
Association of dietary inflammatory potential, dietary oxidative balance score and biological aging DOI
Xuanyang Wang,

S Sarker,

Licheng Cheng

et al.

Clinical Nutrition, Journal Year: 2023, Volume and Issue: 43(1), P. 1 - 10

Published: Nov. 15, 2023

Language: Английский

Citations

28
Association of weight-adjusted waist index with all-cause mortality among non-Asian individuals: a national population-based cohort study DOI Creative Commons
Ting Cao, Ruijie Xie,

Jiusong Wang

et al.

Nutrition Journal, Journal Year: 2024, Volume and Issue: 23(1)

Published: June 12, 2024

The Weight-Adjusted Waist Index (WWI) is a new indicator of obesity that associated with all-cause mortality in Asian populations. Our study aimed to investigate the linear and non-linear associations between WWI non-Asian populations United States, whether was superior traditional indicators as predictor mortality.

Language: Английский

Citations

12
Oral Transfer of Anti-Aging Substances: Key Chemical Found in Reproductive Caste of Termites DOI Open Access
Xin Peng, Zahid Khan, Yanan Dong

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(4), P. 1543 - 1543

Published: Feb. 12, 2025

With the rapid increase in global population aging, incidence and mortality rates of age-related diseases are rising, becoming a worldwide issue. Therefore, researching discovering natural compounds with anti-aging properties is crucial. Social insects such as termites exhibit significant differences lifespan between reproductive non-reproductive castes. Reproductive castes exclusively fed by worker through trophallaxis, providing convenient model for discovery compounds. This thesis systematically investigates trophallactic fluid among different caste members termite Reticulitermes labralis. A total 1028 metabolites were identified fluid, seven which have been validated KEGG database to possess functions. indicates that indeed contains promote longevity. Using "fishing method", we successfully screened out potential life-extending compounds, including IDA (trans-3-indoleacrylic acid). Preliminary experimental results showed influences modulating IIS (insulin/insulin-like growth factor signaling) pathway RAS pathway. Notably, modulation does not require involvement foxoa. Our research findings suggest extended diet-related lifespan-extending effects these nutritionally regulated conserved across taxa.

Language: Английский

Citations

1
Association of nutritional and inflammatory status with all-cause and cardiovascular mortality in adults with sarcopenia: Insights from NHANES DOI
Yang Yang,

Si Shen,

Xiang Luo

et al.

Maturitas, Journal Year: 2025, Volume and Issue: 196, P. 108233 - 108233

Published: March 4, 2025

Language: Английский

Citations

1
A positive association between high dietary medium-chain fatty acids intake and depression: Mediation of inflammation DOI
L.-H. Zeng, Fengping Zhang

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

1
Associations between cadmium exposure and whole-body aging: mediation analysis in the NHANES DOI Creative Commons
Ya Zhang, Mingjiang Liu, Ruijie Xie

et al.

BMC Public Health, Journal Year: 2023, Volume and Issue: 23(1)

Published: Aug. 31, 2023

Even though cadmium (Cd) exposure and cellular senescence (telomere length) have been linked in previous studies, composite molecular aging biomarkers are more significant reliable factors to consider when examining the connection between metal health outcomes. The purpose of this research was assess association urinary (U-Cd) whole-body (phenotypic age).Phenotypic age calculated from chronological 9 biomarkers. Multivariate linear regression models, subgroup analysis, smoothing curve fitting were used explore nonlinear relationship U-Cd phenotypic age. Mediation analysis performed mediating effect on smoking age.This study included 10,083 participants with a mean 42.24 years 42.34 years, respectively. In fully adjusted model, there positive [2.13 per 1 ng/g U-Cd, (1.67, 2.58)]. This differed by sex, age, subgroups (P for interaction < 0.05). mediated serum cotinine proportion 23.2%.Our results suggest that high levels Cd associated aging.

Language: Английский

Citations

19
Association of cardiovascular health and periodontitis: a population-based study DOI Creative Commons

Haitao Qu,

Shengnan Zhang

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Feb. 12, 2024

Abstract Background There is a strong association between cardiovascular disease (CVD) and periodontitis. This study utilized the Life Essentials 8 (LE8) score, composite measure of health (CVH), to elucidate relationship CVH Methods Data from 8,649 nationally representative participants in National Health Nutrition Examination Survey (NHANES) were analyzed. The independent variable our was score (a higher indicates better health), dependent presence or absence periodontitis investigated using weighted multivariable logistic regression models restricted cubic spline (RCS). We controlled for potential confounders such as age, sex, race, education, socioeconomic status minimize bias. Results negative total odds After adjusting all covariates, 10-point increase associated with 10% lower [0.90 (0.87, 0.93)]. Participants had 40% compared those CVH. Socioeconomic (education income) modified this ( P interaction < 0.05). Conclusion Our suggests that health, indicated by scores, reduced likelihood among US adults. appears be influenced status, emphasizing need targeted interventions populations status.

Language: Английский

Citations

7
Association between dietary inflammatory index and chronic kidney disease in middle-aged and elderly populations DOI Creative Commons

Meiqian Guo,

Yi Lei, Xueqing Liu

et al.

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: Jan. 17, 2024

Background A link between food-induced inflammation and common chronic diseases has been identified in studies. However, there was uncertainty about the influence of dietary inflammatory potential on risk kidney disease (CKD) among middle-aged older groups. Our research aimed to examine connection index (DII) CKD people aged 40 years older. Methods This study comprised ten cycles National Health Nutrition Examination Survey (NHANES) from 1999 2018. Linear associations DII with CKD, low-eGFR, albuminuria were examined using multiple logistic regression, whereas non-linear assessed by smoothed curve fitting. Besides, we conducted subgroup analyses interaction tests. Results Of 23,175 individuals, a total 5,847 suffered making up 25.23% all participants. After adjustment for covariates, found that increased scores positive an hazard (OR = 1.08, 95% CI: 1.05, 1.10, p &lt; 0.0001), same shown low-eGFR 1.16, 1.13, 1.19, 0.0001). further converting into categorical variables, above relationship still existed. These relations consistent different ages, genders, BMI, whether smoking, suffering hypertension, diabetes, no significant stratification differences (all P &gt;0.05). Surprisingly, did not find statistically correlation after complete covariates 1.02, 1.00, 0.0742). Even when considered as variable, this relation significant. Furthermore, association shape U fully adjusted model, turning point at 1.6. Conclusion findings indicated persons greater levels had significantly higher CKD.

Language: Английский

Citations

6