Brain Fog and Fatigue following COVID-19 Infection: An Exploratory Study of Patient Experiences of Long COVID

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(23), P. 15499 - 15499

Published: Nov. 23, 2022

Post-acute sequelae of SARS-CoV-2 (PASC) is a poorly understood condition with significant impact on quality life. We aimed to better understand the lived experiences patients PASC, focusing cognitive complaints (“brain fog”) and fatigue (1) daily activities, (2) work/employment, (3) interpersonal relationships. conducted semi-structured qualitative interviews 15 Midwestern academic hospital’s post-COVID-19 clinic. audio-recorded, transcribed, analyzed thematically using combined deductive-inductive approach collected participants’ characteristics from chart review. Participants frequently used descriptive metaphorical language describe symptoms that were relapsing-remitting unpredictable. Fatigue brain fog affected all domains identified subthemes included symptoms’ synergistic effects, difficulty multitasking, lack support, poor self-perception, fear loss income employment. Personal relationships change responsibilities, parenting, social isolation, guilt due burdens placed family. Furthermore, underlying stigma contributed negative emotions, which significantly emotional mental health. Our findings highlight PASC’s patients’ lives. Providers can support COVID-19 survivors during their recovery by identifying needs in sensitive timely manner.

Language: Английский

---

Brain Fog: a Narrative Review of the Most Common Mysterious Cognitive Disorder in COVID-19

Molecular Neurobiology, Journal Year: 2023, Volume and Issue: 61(12), P. 9915 - 9926

Published: Oct. 24, 2023

Language: Английский

---

A New Look on Long-COVID Effects: The Functional Brain Fog Syndrome

Journal of Clinical Medicine, Journal Year: 2022, Volume and Issue: 11(19), P. 5529 - 5529

Published: Sept. 21, 2022

Epidemiological data and etiopathogenesis of brain fog are very heterogeneous in the literature, preventing adequate diagnosis treatment. Our study aimed to explore relationship between fog, neuropsychiatric cognitive symptoms general population. A sample 441 subjects underwent a web-based survey, including PANAS, DASS-21, IES-R, Beck Cognitive Insight Scale, questionnaire investigating demographic information, subjective impairments (Scc) sleep disorders. ANOVA, ANCOVA, correlation multiple stepwise regression analyses were performed. In our sample, 33% participants defined as Healthy Subjects (HS; no Scc), 27% Probable Brain Fog (PBF; or 40% Functional (FBF; plus Scc). PBF FBF showed higher levels than HS, worst psychological outcome. Moreover, worse related female gender, greater symptoms, disorders, rumination/indecision. Being woman more severe predictors severity. pointed out high prevalence various severity suggesting classificatory proposal multifaceted etiopathogenic model, thus facilitating diagnostic therapeutic approaches.

Language: Английский

---

Differences in the Course of Depression and Anxiety after COVID-19 Infection between Recovered Patients with and without a Psychiatric History: A Cross-Sectional Study

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(18), P. 11316 - 11316

Published: Sept. 8, 2022

Background: This study aimed to examine the course of depression and anxiety in COVID-19 survivors with a psychiatric history compared those without history. Methods: A web-based cross-sectional survey for was conducted from July September 2021. total 6016 survivors, accuracy whose responses determined be assured, were included analyses. Exposures time since infection, main outcomes measures severity anxiety, as assessed using Patient Health Questionnaire-9 (PHQ-9) Generalized Anxiety Disorder-7 (GAD-7), respectively. Results: Mean PHQ-9 GAD-7 significantly higher participants than Two-way analysis covariance showed significant effect presence interaction × infection. score revealed infection these factors. Conclusions: The more severe

Language: Английский

---

Gender Disparities in Neurological Symptoms of Long-COVID: A systematic review and meta-analysis

Neuroepidemiology, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 15

Published: Aug. 19, 2024

Background: Female gender is a known risk factor for long COVID. With the increasing number of COVID-19 cases, corresponding survivors also expected to rise. To best our knowledge, no systematic review has specifically addressed differences in neurological symptoms Methods: We included studies on female individuals who presented with specific at least 12 weeks after confirmed diagnosis from PubMed, Central, Scopus, and Web Science. The search limit was put January 2020 until June 15, 2024. excluded that did not provide sex-specific outcome data, those English, case reports, series, articles Results: A total 5,632 eligible were identified. This article provides relevant information involving 6,849 patients, which 3,414 female. sample size ranged 70 2,856, maximum follow-up period 18 months. earliest publication date September 16, 2021, while latest 11, following had significant difference ratio (RR) gender: fatigue RR 1.40 (95% confidence interval [CI]: 1.22–1.60, p < 0.001), headache 1.37 CI: 1.12–1.67, = 0.002), brain-fog 1.38 CI 1.08–1.76, 0.011) depression 1.49 1.2–1.86, anosmia 1.61 1.36–1.90, 0.001). High heterogenicity found fatigue, brain fog, anxiety due diverse methodologies employed studies. Conclusion: Our findings suggest women are higher long-COVID symptoms, including headaches, depression, anosmia, compared men. prevalence these decreases 1 year, based limited data small available beyond this period.

Language: Английский

---

Physical functioning post-COVID-19 and the recovery process: a mixed methods study

Disability and Rehabilitation, Journal Year: 2023, Volume and Issue: 46(8), P. 1570 - 1579

Published: April 20, 2023

Purpose To describe physical functioning after severe COVID-19-infection.Materials and method An explanatory sequential mixed design was used. Thirty-nine participants performed tests answered questionnaires measuring six months hospitalisation due to COVID-19. Thirty of these participated in semi-structured interviews with questions regarding how they perceived their recovery from COVID-19 at 12 post-hospitalisation.Results At months, measured via chair stand test hip-worn accelerometers lower than normal reference values. There a reduction breathing muscle strength. Participants estimated functional status during different activities as compared those before COVID-19-infection, patient-specific scale. one year infection, there were descriptions rough process remaining symptoms.Conclusion Patients recovering seem have reduced activity levels, perceive be slow difficult. They experienced lack clinical support contradictory advice rehabilitation. Coaching returning the infection needs better co-ordinated is need for guidelines health professionals avoid patients receiving advice.

Language: Английский

---

“Three Sides to Every Story”: Living the Patient, Carer and Staff Experience of COVID

Global Qualitative Nursing Research, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 1, 2025

In 2020, the UK’s National Health Service (NHS) braced itself for challenge of COVID pandemic. Older, frail adults were among those at highest risk morbidity and mortality. This study aimed to capture lived experiences patients, families/carers staff on a ward. Thirty participants included, data collected through in-depth unstructured interviews. The analyzed using interpretive phenomenology. Four main themes constructed, capturing collective participants. first theme, changing uncertain period time, describes shared sense immersion in chaotic situation, lack control resulting fears related contagion. Secondly, challenges care, focuses anxieties guilt shortcomings care delivery, efforts adapt new situation. third communication keeping touch, details effect restrictions had maintain contact its toll mental health. last theme challenging situations end-of-life reflects grief loss by all three participant groups. adds growing evidence base around pandemic exploration profound triangulated experience

Language: Английский

---

Opportunities to Improve Long COVID Care: Implications from Semi-structured Interviews with Black Patients

Patient, Journal Year: 2022, Volume and Issue: 15(6), P. 715 - 728

Published: July 30, 2022

Language: Английский

---

Multidisciplinary inpatient rehabilitation for older adults with COVID-19: a systematic review and meta-analysis of clinical and process outcomes

BMC Geriatrics, Journal Year: 2023, Volume and Issue: 23(1)

Published: June 27, 2023

Abstract Background Older adults are at increased risk for disease severity and poorer prognosis following COVID-19 infection. The aim of this systematic review meta-analysis is to explore the impact multidisciplinary rehabilitation in acute or post-acute hospital setting older with COVID-19. Methods Cochrane library, EMBASE, Cinahl Medline (via EBSCO), PubMed, Web Science were systematically searched June 2022 a repeat search was completed March 2023. Screening, data extraction quality appraisal conducted independently by two reviewers. Studies reporting outcomes (provided more Health Social Care Professionals) included. Both observational experimental study designs primary outcome functional ability. Secondary included discharge disposition, unit length stay, mortality, secondary healthcare utilisation, long-term effects Results Twelve studies met inclusion criteria, comprising total 570 adults. Where reported, stayed mean 18 days (95%CI, 13.35- 23.13 days) units 19 15.88–21.79 days). There significant improvement ability among who received (REM, SMD = 1.46, 95% CI 0.94 1.98). proportion discharged directly home ranged from 62 97%. Two reported 2% inpatient mortality rate persons during rehabilitative care. No followed up patients after point no on long term Conclusions Multidisciplinary may result improved units/centres Findings also highlight need further research into effect Future should comprehensively describe terms disciplines involved intervention provided.

Language: Английский

---

Relationship between attitudes toward COVID-19 infection, depression and anxiety: a cross-sectional survey in Japan

BMC Psychiatry, Journal Year: 2022, Volume and Issue: 22(1)

Published: Dec. 19, 2022

Abstract Background Although negative attitudes are known to develop with experiences of COVID-19 infection, it remains unclear whether such contribute depression and anxiety as sequelae COVID-19. We aimed investigate the relationships between attitude towards infection post-COVID-19 anxiety. Methods A cross-sectional survey recovered patients was conducted from July September 2021 in Japan. Outcome variables, were assessed using Patient Health Questionnaire-9 Generalized Anxiety Disorder-7); scores 10 above identified having symptoms anxiety, respectively. Exposure variables participants experiencing following strongly: threat life due helplessness regarding blaming a third party who did not restrain going outside, themselves for their worry about spreading others, self-stigma (Self-Stigma Scale-Short). Modified Poisson regression analyses performed analyze findings. Results total 6016 responses included analyses. The proportion 19.88%, 11.47%. oneself significantly associated after adjusting covariates. Blaming outside There no association others or Conclusion Negative attitudes, including experience related Further studies confirming countermeasures preventing decreasing mitigate these needed.

Language: Английский

---