Chemistry & Biodiversity,
Journal Year:
2023,
Volume and Issue:
20(2)
Published: Jan. 26, 2023
Abstract
In
southern
Brazil,
the
biodiversity
is
great
and
traditional
use
of
medicinal
plants
for
wound
healing
has
been
documented
in
ethnobotanical
studies
pharmacological
have
assessed
their
properties
phytochemistry.
Therefore,
this
study
evaluated
surveys
regarding
used
Brazil
about
these
published
between
2000
2022.
To
retrieve
articles
related
to
study,
Web
Science,
PubMed
(NLM),
Open
Access
Journals,
Scielo,
Lilacs,
Google
Scholar,
with
keywords
including
plants,
healing,
South
used.
As
a
result,
73
belonging
39
families
were
found
as
resource
15
which
cited
more
than
once.
Besides,
14
also
agents
worldwide.
The
most
plant
actions
was
Symphytum
officinale
L.
(comfrey).
From
date,
44
scientifically
demonstrated
wound‐healing
effects
Brazilian
reviewed.
folk
medicine
presents
variety
purposes,
scientific
data
some
those
plants.
However,
many
yet
be
investigated,
current
literature
still
needs
phytochemical
information
studied.
Aside
from
this,
future
focus
should
on
standardization
herbal
extracts,
further
research
required
investigate
mechanisms.
Clinical
area
remains
its
infancy
warrants
robust
clinical
studies.
Gels,
Journal Year:
2023,
Volume and Issue:
9(7), P. 539 - 539
Published: July 3, 2023
Aloe
vera-based
hydrogels
have
emerged
as
promising
platforms
for
the
delivery
of
therapeutic
agents
in
wound
dressings
due
to
their
biocompatibility
and
unique
wound-healing
properties.
The
present
study
provides
a
comprehensive
overview
recent
advances
application
healing.
synthesis
methods,
structural
characteristics,
properties
are
discussed.
Mechanisms
released
from
hydrogels,
including
diffusion,
swelling,
degradation,
also
analyzed.
In
addition,
effects
on
healing,
well
reduction
inflammation,
antimicrobial
activity,
tissue
regeneration,
highlighted.
incorporation
various
agents,
such
anti-inflammatory
ones,
into
is
reviewed
detail.
Furthermore,
challenges
future
prospects
dressing
applications
considered.
This
review
valuable
information
current
status
highlights
potential
improve
healing
outcomes.
Frontiers in Pharmacology,
Journal Year:
2022,
Volume and Issue:
13
Published: Aug. 24, 2022
Use
of
medicinal
plants
and
herbs
in
the
treatment
management
diseases,
including
diabetes
mellitus
its
complications
remains
an
integral
part
African
tradition.
In
Zimbabwe,
nearly
one
million
people
are
living
with
mellitus.
The
prevalence
Zimbabwe
is
increasing
every
year
due
to
lifestyle
changes,
has
accelerated
use
traditional
medicines
for
urban
areas.
addition,
high
cost
modern
medicine
led
many
rural
parts
rely
on
herbal
plant
complications.
This
review
highlights
a
number
studies
carried
out
evaluate
antidiabetic
properties
indigenous
found
goal
treating
Further,
we
discuss
mechanism
action
various
extracts
Together,
this
article
can
open
pathways
leading
discovery
new
derived
regularization
crude
remedies
treat
by
Zimbabwean
government
others
across
Africa.
Paulo Sérgio da Paz Silva Filho eBooks,
Journal Year:
2023,
Volume and Issue:
unknown, P. 177 - 187
Published: Jan. 1, 2023
do
Esporte,
a
educação
física,
odontologia,
psicologia,
terapia
ocupacional,
nutrição,
fisioterapia
e
engenharia
biomédica,
entre
outras.As
ciências
da
International Wound Journal,
Journal Year:
2023,
Volume and Issue:
20(10), P. 4394 - 4409
Published: July 12, 2023
Abstract
Diabetic
foot
ulcer
(DFU),
a
common
intractable
chronic
complication
of
diabetes
mellitus
(DM),
has
prevalence
up
to
25%,
with
more
than
17%
the
affected
patients
at
risk
amputation
or
even
death.
Vascular
factors,
including
vascular
stenosis
occlusion,
dyslipidemia,
impaired
neurosensory
and
motor
function,
skin
infection
caused
by
trauma,
all
increase
DFU
in
diabetes.
Therefore,
diabetic
is
not
single
pathogenesis.
Preclinical
studies
have
contributed
greatly
pathogenesis
determination
efficacy
evaluation
DFU.
Many
therapeutic
tools
are
currently
being
investigated
using
animal
models
for
effective
clinical
translation.
However,
preclinical
that
completely
mimic
remain
unexplored.
this
review,
preparation
methods
criteria
three
major
pathological
mechanisms:
neuropathy,
angiopathy
were
discussed
detail.
And
advantages
disadvantages
various
sign
simulation.
Furthermore,
current
status
vitro
some
been
transformed
into
treatment
programs,
such
as
medical
dressings,
growth
factor
therapy,
3D
bioprinting
pre‐vascularization,
Traditional
Chinese
Medicine
treatment.
because
complexity
mechanism
DFU,
transformation
model
still
faces
many
challenges.
We
need
further
optimize
existing
provide
an
platform
future
study
pathophysiology
Pharmacological Research - Modern Chinese Medicine,
Journal Year:
2023,
Volume and Issue:
8, P. 100291 - 100291
Published: July 18, 2023
:
Aloe
vera
L.
Burman
(AV)
is
a
semi-tropical
plant
with
many
medicinal
applications
including
wound
healing,
antioxidant,
anti-inflammatory,
and
anticancer
properties.
It
used
in
Chinese
medicine
to
treat
diabetes,
hypertension,
infection,
dermatitis.
The
flowers
of
contain
volatile
compounds
ascorbic
acid,
the
leaves
are
good
source
organic
acids,
phenols,
enzymes,
minerals
while
rind
contains
pectin,
lignin,
polysaccharides.
This
study
evaluated
total
phenol,
flavonoid,
tannin
contents
aqueous
methanol
extracts
as
well
reducing
power
1,1-Diphenyl-2-picrylhydrazyl
(DPPH)
radical
scavenging
activities.
were
extracted
using
maceration
technique.
tannin,
flavonoid
both
estimated
standard
methods.
In-vitro
antioxidant
activities
(reducing
activity
DPPH
free
activity)
also
EC50
IC50
Non-Linear
Regression.
Both
AV
revealed
presence
tannins,
flavonoids.
extract
produced
better-reducing
(EC50=
249316
µg/ml)
compared
463045
better
(IC50=
54.0
103.4
µg/ml).
two
attributed
suggests
that
different
plants
ascribed
solvent
polarity.
