Driving Role of Zinc Oxide Nanoparticles with Different Sizes and Hydrophobicity in Metabolic Response and Eco-Corona Formation in Sprouts (Vigna radiata)

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(22), P. 9875 - 9886

Published: May 9, 2024

Zinc oxide nanoparticles (ZnO NPs) cause biotoxicity and pose a potential ecological threat; however, their effects on plant metabolism eco-corona evolution between NPs organisms remain unclear. This study clarified the molecular mechanisms underlying physiological metabolic responses induced by three different ZnO with sizes hydrophobicity in sprouts (

Language: Английский

---

The road ahead for functional foods: Promising opportunities amidst industry challenges

Future Postharvest and Food, Journal Year: 2024, Volume and Issue: 1(2), P. 266 - 273

Published: June 1, 2024

Functional foods, fortified with bioactive compounds, offer health benefits beyond basic nutrition. Despite their potential, challenges such as compound instability, scalability issues, and regulatory gaps exist. This commentary explores role, market dynamics, future trends, emphasizing the need for ongoing research effective regulations. In dynamic field of nutrition science, functional foods have carved a significant niche. These which more than just nutrition, are compounds antioxidants (e.g., phenolic carotenoids, omega-3 fatty acids, some vitamins) that confer health-promoting disease-preventing properties (Barik et al., 2022; Khan 2013). The concept amalgamates principles from food pharmacology, thereby offering comprehensive approach to well-being (Granato 2020). rise in interest is driven by shift consumer preference toward natural health-enhancing products (Baker 2022a; Topolska 2021). As societies become increasingly health-conscious, there burgeoning demand can enhance health, boost performance, mitigate risk disease. trend mirrored rapid expansion market, projected witness substantial growth coming years (Vergari 2010). However, journey laboratory laden challenges. encompass technical issues related stability bioavailability hurdles, acceptance/trust. these challenges, potential realm personalized nutrition) delivery compounds) microorganisms probiotics) vast (Ahluwalia, 2021; Gupta Personalized particular, customizes dietary recommendations individual nutritional needs, holds revolutionize wellness near (Gupta capacity deliver targeted benefits, ideally suited this approach. harnessing necessitates overcoming scientific, regulatory, (Khan 2013; Nazir 2019). current landscape scientific literature, an abundance trending publications focusing on topic foods. despite wealth information available, noticeable void when it comes concise overview captures various facets gap particularly evident areas applications within industry. Accordingly, aims provide exhaustive role opportunities they present both consumers industry, exist exciting development road. It delves into effects bioactives, dynamics decline supplements preventive strategies, increasing awareness healthier products. paper also discusses space corresponding including manufacturing process, toxicity, lack clear regulations, limited data clinical translation, skepticism/awareness. concludes discussion trends effect future. Bioactive diverse group molecules (Kamiloglu Kumar 2023). They exhibit range antioxidant, anti-inflammatory, antimicrobial, antiatherogenic, antithrombotic, cardioprotective, vasodilatory Mohamed, 2015). Antioxidants, instance, known combat free radicals, implicated several different human diseases (Arshad & Ahmad, found variety fruits, herbs, spices, vegetables, cereals, legumes, chocolate, beverages like tea, coffee, or wine (Mohamed, derived plants, biologically active proteins, polyphenols, phytosterols, biogenic amines, carotenoids conditions cancer, cardiovascular diseases, diabetes (Samtiya efficacy depends bioavailability, be influenced factors matrix, processing, storage, differences (Berkel Kaşıkçı, 2023; de Freitas Queiroz Barros, Baú Betim Cazarin, Maróstica Junior, 2022). Bioavailability denotes degree speed at component (i.e., drug metabolite) absorbed systemic circulation, thus reaching its action site. Unfortunately, oral significantly impacted release plant solubility gastrointestinal fluid, permeability through intestinal epithelial cells, enzymatic chemical reactions taking place tract Barros Nonetheless, hold promise promoting preventing chronic diseases. Further yet needed fully understand influencing optimize maximum benefits. Beyond plant-derived important acknowledge animal sources microorganisms. For often fish, been widely recognized anti-inflammatory cardioprotective effects. Similarly, probiotics, beneficial microorganisms, associated improved gut immune function (Grand View Research, examples underscore diversity sources. progresses, anticipated will discovered utilized further emphasizes safety profiles, well develop systems compounds. global was valued USD 280.7 billion 2021, expand annual rate 8.5% 2022 2030 surge, has US illustrated Figure 1, number crucial elements. magnitude upcoming years. One primary drivers rising fortifying additives. aware impact physical mental well-being, seeking out not only satisfy hunger but additional led surge ingredients vitamins, minerals, fibers, acids (Hilton, 2017). Another factor contributing consciousness among consumers. With prevalence lifestyle-related rise, individuals making changes improve prevent disease (Daliri Lee, Functional/fortified added meet growing demand. aging population another critical driver market. people age, needs change, play meeting needs. calcium vitamin D help older adults maintain bone while those enriched support heart (van der Zanden, van Kleef, Wijk, Trijp, 2014). incidence Chronic disease, diabetes, cancer prevalent, diet plays prevention management properties, therefore becoming essential part strategies 2015; Essa summary, experiencing growth, additives, consumers, population, continue, expected reach new heights While supplement witnessing slowdown, categories even observing negative rates (Natarajan GR, Wróbel suggests perceived holistic Kengpol saw astronomical sales gains over past few years, see normalize. seeing first time long while, industry still good place. 10% between 2020 C cold-and-flu ingredient category were $586 million. Nevertheless, does spell doom indicates Preventive focus maintaining diet, gaining popularity (Bhargava, 2010; Control Prevention, Sharma, Luxita, Yadav, Akanksha, due (Sharma Singh, practical sustainable promotion, context healthcare costs burden (Boone-Villa 2019; contain scavenge radicals show anti-mutagenic, anti-tumor, neuroprotective certain physiological response reducing (Barik, Chowdhury, Tewari), promotion. Consumers well-being. heightened driving alternatives synthetic additives Bogue Repar, antioxidants, seen holistic, interested content 2022a). reflected probiotics. force behind equally ensure well-informed misled claims (Van Kleef 2005; Williams Ghosh, 2008). Misleading create false perceptions about lead unhealthy choices (Williams Therefore, education communication key ensuring make informed diet. Educational programs increase consumers' understanding initiatives distinguish scientifically substantiated potentially misleading (Franco-Arellano 2017; overall, said health-conscious increasing. numerous pose used change yield increases small large quantities (Bansal, Poonia, Kolluri, Vasundhara, Sharma affect taste, texture, final product. characteristics containing vegetable extracts bioactives vary depending type (Aqilah Moreover, unstable degrade during processing storage. instability result loss efficacy. example, susceptible oxidative degradation, chemically (Kandemir compromises minimizes breakdown processes substances reveal C, phenols, flavonoids, glycosides interact oxygen convective drying phase, especially elevated temperatures. interaction leads reduction high reducibility (Belwal ElGamal Thus, careful consideration control storage incorporated Scaling up production, indeed complex process meticulous planning execution. scaling simple multiplying quantities. When quantities, change. product may behave same way, so methods adjusted changed achieve desired result. peptides, foodstuffs values, face terms original bioactivity under (Hosseini specific manufacture, finished taste texture. Changes sourcing formula adjustments, operational complexities faced scale-up (Galanakis, Sutton 2016). Sourcing larger business ways. rewrite hit price point, unnecessary delays. use novel technologies require modifications existing processes, complicating (Avelar Galanakis, production necessary demand, presents Overcoming requires planning, execution, possibly assistance experts. Food encompasses multiple aspects, safe implementation hygienic proper preparation methods. extends fortification consumption provided. pursuit overlook safety. continues evolve, must remain forefront research, development, regulation efforts. Additionally, although nanoparticles promising avenue enhancing toxicity concern (Kang Rath minute particles, unique biological ways particles cannot, leading harmful (Sukhanova 2018). rigorous evaluations do health. isolated amounts, toxic concentrations (Mlozi 2020; Nana 2011). secondary metabolites produced playing defense mechanisms, reproduction systems, concentration At concentrations, adverse effects, stress, DNA damage, apoptosis, cell death, induction inflammatory responses Vilas-Boas dosage compounds/ingredients Regulations country (Birch Bonwick, Brown Chan, Heller, 2001; Hoadley, clear, universal regulations uncertainty manufacturers. far, Japan definition approval (Díaz contrast, United States Canada attempted define absence framework. Europe, European Union adopted working Europe-wide ambiguity confusion skepticism, undermining credibility On other hand, (Sato Valls well-defined framework successful ensures builds trust acceptance. Such would products, foster trust, ultimately, Several countries excelled setting benchmarks rest world. Japan, pioneer field, introducing term "FOSHU" (Foods Specified Health Use) classify Japanese government implemented stringent standards marketing Finland made strides area, Finnish Authority actively balanced States, FDA regulates conventional requirements claims. involves review provides claimed highlight importance acceptance similar measures harness full There enough valid evidence promotion (Mohanty Singhal, 2018; Samtiya demonstrated translation. refers applying discoveries gleaned laboratory, clinical, studies (Homer-Vanniasinkam Tsui, 2012; Mlozi More how body validate precise mechanisms exert understood (de Kang Furthermore, depend presence Wijesekara Xu, hinder professionals Healthcare hesitant recommend robust supporting skeptical if perceive backed solid 2022b). our 2022a, Baker 2021) rapidly, skepticism remains doubt fueled (Topolska Van 2005). suggest correlation intake possible advantages. globally accepted influences amount proof required assertions across nations. themselves adequate proof; comprehend significance underpins assertions. differing views regarding actual Some believe primarily promoted strategy rather customers/consumers (English, Vergari labels promote criticized (Siro 2008; observations done better inform linked consuming underscores transparent manufacturers production: mentioned earlier (Section 3.2), (Subramanian Anandharamakrishnan, Regulatory uncertainties: stated Section 3.4, (Brown Díaz 2001). Grand Need investment development: development. includes developing conducting trials (Heller, Homer-Vanniasinkam 2012). grow, companies likely enter To date, nations, corporations BASF, Cargill, General Mills Inc., GFR Pharma, Nutri-Nation, Amway, Arla Foods appear channeling resources endeavors undertaking strategic measures, fortify standing edge expansion, propelled merely momentary trend, reflection broader societal attitudes educated path manufacturing, data, all hurdles overcome. multidisciplinary brings together researchers, regulators, looks promising. Advancements technology paving way innovative solutions, approaches production. Simultaneously, helping build foundation field. one thing clear: we continue explore safe, sustainable, accessible all. open dialogue stakeholders. concerted efforts, truly live Ali Rashidinejad: Conceptualization; investigation; funding acquisition; writing - draft; methodology; validation; editing; software; project administration; resources. author declares no competing financial interest. Data sharing applicable article created analyzed.

Language: Английский

---

Proteomics technologies in toxicity screening: a review

Environmental Chemistry Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 3, 2025

Language: Английский

---

A Review on Biosynthesis of Nanoparticles via Microalgal Technology and Their Biomedical Applications

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)

Published: Feb. 7, 2025

Language: Английский

---

Production of biomaterials and biochemicals from lignocellulosic biomass through sustainable approaches: current scenario and future perspectives

Deleted Journal, Journal Year: 2025, Volume and Issue: 2(1)

Published: March 9, 2025

Language: Английский

---

Nanoparticles as Elicitors and Harvesters of Economically Important Secondary Metabolites in Plants

Reference series in phytochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 1191 - 1240

Published: Jan. 1, 2025

Language: Английский

---

Design of Bombyx mori (B. mori) Silk Fibroin Microspheres for Developing Biosafe Sunscreen

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(13), P. 15798 - 15808

Published: March 20, 2024

Sunscreens play a crucial role in protecting the skin from ultraviolet (UV) damage. However, present commercial sunscreens have tendency to generate free radicals UV window, resulting serious inflammatory responses and health problems. In this study, we demonstrate that silk fibroin microspheres (SFMPs) assembled regenerated (SF) could scavenge while preventing irradiation thus promising sunscreen. The SFMP reflected more light than SF presented higher stability of organic sunscreens. vitro analysis proved efficiently hydroxy radical reduce intracellular reactive oxygen titanium dioxide (TiO2). vivo experiments exhibited provided stronger protection against TiO2. Furthermore, treatment significantly inhibited response. This work suggests has great potential be developed into biosafe

Language: Английский

---

ProteinsPlatform constructed from biofuctionalized-magnetized nano-chitosan for efficient separation of multi-tagged fusion proteins

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 496, P. 154077 - 154077

Published: July 18, 2024

Language: Английский

---

Design and construction of magnetic nanomaterials and their remediation mechanisms for heavy metal contaminated soil

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 951, P. 175369 - 175369

Published: Aug. 8, 2024

Language: Английский

---

Investigating the dynamic responses of Aegilops tauschii Coss. to salinity, drought, and nitrogen stress: a comprehensive study of competitive growth and biochemical and molecular pathways

Frontiers in Plant Science, Journal Year: 2023, Volume and Issue: 14

Published: Sept. 6, 2023

(Coss.) is a highly deleterious, rapidly proliferating weed within the wheat, and its DD genome composition exhibits adaptability toward diverse abiotic stresses demonstrates heightened efficacy in nutrient utilization. Current study investigated different variegated impacts of distinct nitrogen concentrations with varied plant densities, scrutinizing behavior

Language: Английский

---