Analytical and Bioanalytical Chemistry,
Journal Year:
2024,
Volume and Issue:
416(24), P. 5303 - 5316
Published: Aug. 12, 2024
Herein
we
introduce
a
novel
water-based
graphite
ink
modified
with
multiwalled
carbon
nanotubes,
designed
for
the
development
of
first
wearable
self-powered
biosensor
enabling
alcohol
abuse
detection
through
sweat
analysis.
The
stencil-printed
(SPG)
electrodes,
printed
onto
flexible
substrate,
were
by
casting
nanotubes
(MWCNTs),
electrodepositing
polymethylene
blue
(pMB)
at
anode
to
serve
as
catalyst
nicotinamide
adenine
dinucleotide
(NADH)
oxidation,
and
hemin
cathode
selective
H
Cell Reports Physical Science,
Journal Year:
2024,
Volume and Issue:
5(2), P. 101801 - 101801
Published: Jan. 31, 2024
With
recent
advances
in
point-of-care
testing,
wearable
electronics,
and
implantable
medical
devices,
there
is
a
growing
interest
developing
state-of-the-art
methods
to
monitor
human
health
conveniently
dynamically.
Among
these
methods,
electrochemical
biosensors
have
offered
unique
opportunity
transform
lab-in-hospital
lab-around-body
lab-on-body.
In
an
biosensing
system,
appropriate
bioreceptors
that
could
specifically
recognize
capture
target
molecules
pose
significant
impact
on
the
performance
of
biosensors.
Thus,
this
review
systematically
explores
different
types
their
immobilization
utilized
for
detection
wide
range
biomarkers
clinical
applications.
Moreover,
it
delves
into
principles
behind
operation
provides
insights
challenges
limitations
associated
with
use
practical
settings.
Furthermore,
proposes
possible
strategies
overcome
existing
order
stimulate
further
research
implementation
larger
scale.
ACS Sensors,
Journal Year:
2024,
Volume and Issue:
9(3), P. 1149 - 1161
Published: March 13, 2024
Interstitial
fluid
(ISF)
has
attracted
extensive
attention
in
an
extremely
wide
range
of
areas
due
to
its
unique
advantages,
such
as
portability,
high
precision,
comfortable
operation,
and
superior
stability.
In
recent
years,
the
microneedle
(MN)
technique
been
considered
be
excellent
tool
for
extracting
ISF
because
it
is
painless
noninvasive.
Recent
reports
have
shown
that
MN
good
application
prospects
extraction.
this
review,
we
provide
comprehensive
in-depth
insight
into
integrated
devices
detection,
covering
basic
structure
well
fabrication
various
applications
Challenges
are
highlighted,
with
a
discussion
on
how
transition
MN-integrated
toward
personalized
healthcare
monitoring
systems.
Biosensors,
Journal Year:
2023,
Volume and Issue:
13(4), P. 456 - 456
Published: April 3, 2023
Food
security
is
significantly
affected
by
the
mass
production
of
agricultural
produce
and
goods,
growing
number
imported
foods,
new
eating
consumption
habits.
These
changed
circumstances
bring
food
safety
issues
arising
from
spoilage
to
fore,
making
control
essential.
Simple
fast
screening
methods
have
been
developed
detect
pathogens
biomarkers
indicating
freshness
for
safety.
In
addition
traditional,
sequential,
chemical
analytical
microbiological
methods,
fast,
highly
sensitive,
automated
suitable
serial
tests
appeared.
At
same
time,
biosensor
research
also
developing
dynamically
worldwide,
both
in
terms
analytes
be
determined
technical
toolkit.
Consequently,
rapid
development
biosensors,
including
electrochemical-based
has
led
significant
advantages
quantitative
detection
contaminants.
techniques
show
great
specificity
tested
provide
adequate
accuracy
even
complex
matrices.
our
review
article,
we
summarize,
separate
chapters,
electrochemical
biosensors
most
important
groups
they
can
ensure,
with
particular
respect
meat
fish
products,
milk
dairy
as
well
alcoholic
non-alcoholic
beverages.
Advanced Sensor Research,
Journal Year:
2023,
Volume and Issue:
3(3)
Published: April 25, 2023
Abstract
Herein,
this
work
reports
the
first
example
of
second‐generation
wearable
biosensor
arrays
based
on
a
printed
electrode
technology
involving
water‐based
graphite
ink,
for
simultaneous
detection
l
‐lactate
and
d
‐glucose.
The
ink
is
deposited
onto
flexible
polyethylene
terephthalate
sheet,
namely
stencil‐printed
(SPG)
electrodes,
further
modified
with
[Os(bpy)
2
(Cl)(PVI)
10
]
as
an
osmium
redox
polymer
to
shuttle
electrons
from
center
lactate
oxidase
Aerococcus
viridans
(LOx)
gluocose
Aspergillus
niger
(GOx).
proposed
array
exhibits
limit
low
(9.0
±
1.0)
×
−6
m
LOx/SPG‐[Os(bpy)
(3.0
0.5)
GOx/SPG‐[Os(bpy)
],
sensitivity
high
1.32
μA
−1
28.4
].
also
selective
when
tested
in
buffer
artificial
sweat
endowed
operational/storage
stability
≈80%
initial
signal
retained
after
20
days.
Finally,
integrated
wristband
successfully
continuous
monitoring
‐glucose
healthy
volunteer
during
daily
activity.
This
foreseen
real‐time
device
sport‐medicine
healthcare
applications.
Chemosensors,
Journal Year:
2023,
Volume and Issue:
11(6), P. 346 - 346
Published: June 14, 2023
This
paper
describes
the
development
of
a
novel
glucose
biosensor
through
layer-by-layer
technique
(LbL).
The
self-assembled
architectures
were
composed
positive-charged
silsesquioxane
polyelectrolyte,
3-n-propylpyridinium
chloride
(SiPy+Cl−),
nickel
(II)
tetrassulphophthalocyanine
(NiTsPc),
and
conductive
surface
FTO
(fluor
tin
oxide).
construction
was
influenced
by
isoelectric
point
(pI)
oxidase
enzyme
(GOx),
which
allowed
electrostatic
interaction
between
outer
layer
film
enzyme.
architecture
modified
electrode
GOx/(SiPy+Cl−/NiTsPc)5.5/FTO
confirmed
UV-Vis,
FTIR,
chronoamperometry
techniques
using
different
immobilization
methods
GOx.
Among
studied
methods,
higher
variation
current
observed
for
formed
mixed
LbL
films
SiPy+Cl−
NiTsPc
immobilized
drop
coating.
stability
reproducibility
verified
when
last
containing
coated
with
0.2%
Nafion®
polymer.
Under
these
conditions,
linear
response
obtained
in
concentration
range
0.2
to
1.6
mmol
L−1
(R2
=
0.991)
limit
detection
0.022
L−1.
proposed
applied
quantify
two
samples
kombucha
juices
accuracy,
allowing
content
healthy
beverages
be
estimated.
Biosensors and Bioelectronics,
Journal Year:
2023,
Volume and Issue:
237, P. 115450 - 115450
Published: June 15, 2023
Herein,
we
report
a
scalable
benchtop
electrode
fabrication
method
to
produce
highly
sensitive
and
flexible
third-generation
fructose
dehydrogenase
amperometric
biosensors
based
on
water-dispersed
0D-nanomaterials.
The
electrochemical
platform
was
fabricated
via
Stencil-Printing
(StPE)
insulated
xurography.
Carbon
black
(CB)
mesoporous
carbon
(MS)
were
employed
as
0D-nanomaterials
promoting
an
efficient
direct
electron
transfer
(DET)
between
(FDH)
the
transducer.
Both
nanomaterials
prepared
in
water-phase
sonochemical
approach.
nano-StPE
exhibited
enhanced
electrocatalytic
currents
compared
conventional
commercial
electrodes.
enzymatic
sensors
exploited
for
determination
of
D-fructose
model
solutions
various
food
biological
samples.
StPE-CB
StPE-MS
integrated
showed
appreciable
sensitivity
(∼150
μA
cm-2
mM-1)
with
μmolar
limit
detection
(0.35
0.16
μM,
respectively)
extended
linear
range
(2-500
1-250
respectively);
selectivity
biosensors,
ensured
by
low
working
overpotential
(+0.15
V),
has
been
also
demonstrated.
Good
accuracy
(recoveries
95
116%)
reproducibility
(RSD
≤8.6%)
achieved
urine
proposed
approach
because
manufacturing
versatility
electro-catalytic
features
water-nanostructured
0D-NMs
opens
new
paths
affordable
customizable
FDH-based
bioelectronics.
Faraday Discussions,
Journal Year:
2024,
Volume and Issue:
250, P. 9 - 42
Published: Jan. 1, 2024
While
a
substantial
amount
of
research
activity
has
been
conducted
in
fields
related
to
organic
photonics
and
electronics,
including
the
development
devices
such
as
field-effect
transistors,
photovoltaics,
light-emitting
diodes
for
applications
encompassing
thermoelectrics,
batteries,
excitonic
materials
photochemical
optoelectronic
applications,
this
perspective
review
will
primarily
concentrate
on
emerging
rapidly
expanding
domain
bioelectronics
neuromorphics.
Here
we
present
most
recent
findings
transistors
capable
sensing
biological
biomarkers
down
at
single-molecule
level
(
