
Biomedical Technology, Journal Year: 2024, Volume and Issue: 8, P. 17 - 49
Published: Oct. 1, 2024
Language: Английский
Biomedical Technology, Journal Year: 2024, Volume and Issue: 8, P. 17 - 49
Published: Oct. 1, 2024
Language: Английский
Composites Part B Engineering, Journal Year: 2022, Volume and Issue: 250, P. 110437 - 110437
Published: Nov. 26, 2022
Language: Английский
Citations
19International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 235, P. 123738 - 123738
Published: Feb. 18, 2023
Language: Английский
Citations
11International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 264, P. 130573 - 130573
Published: March 4, 2024
Language: Английский
Citations
4Materials Today Bio, Journal Year: 2025, Volume and Issue: 30, P. 101461 - 101461
Published: Jan. 5, 2025
Language: Английский
Citations
0Advanced Science, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 14, 2025
Abstract Studying the molecular basis of intestinal infections caused by enteric pathogens at tissue level is challenging, because most human infection models have limitations, and results obtained from animals may not reflect situation. Infections with Salmonella enterica serovar Typhimurium (STm) different outcomes between organisms. 3D modeling primary material provides alternatives to animal experimentation, but epithelial co‐culture immune cells remains difficult. Macrophages, for instance, contribute immunocompetence native tissue, yet their incorporation into challenging. A immunocompetent model small intestine based on decellularized submucosa enriched monocyte‐derived macrophages (MDM) established. The multicellular recapitulated in vivo‐like cellular diversity, especially induction GP2 positive microfold (M) cells. Infection studies STm reveal that pathogen physically interacts these M‐like MDMs show trans‐epithelial migration phagocytosed within levels inflammatory cytokines are induced upon infection. Infected shed supernatant, potentially reflecting an intracellular reservoir invasion‐primed STm. Together, epithelium bears potential as alternative identify human‐specific processes underlying bacterial infections.
Language: Английский
Citations
0Surface and Coatings Technology, Journal Year: 2025, Volume and Issue: unknown, P. 131814 - 131814
Published: Jan. 1, 2025
Language: Английский
Citations
0Materials & Design, Journal Year: 2025, Volume and Issue: unknown, P. 113711 - 113711
Published: Feb. 1, 2025
Language: Английский
Citations
0Biomaterials Advances, Journal Year: 2025, Volume and Issue: unknown, P. 214291 - 214291
Published: March 1, 2025
Language: Английский
Citations
0Regenerative Engineering and Translational Medicine, Journal Year: 2025, Volume and Issue: unknown
Published: April 30, 2025
Language: Английский
Citations
0Expert Opinion on Drug Delivery, Journal Year: 2023, Volume and Issue: 20(11), P. 1511 - 1530
Published: Oct. 29, 2023
The application of DNA framework nucleic acid materials in the biomedical field has witnessed continual expansion. Among them, tetrahedral acids (tFNAs) have gained significant traction as foremost biological vectors due to their superior attributes editability, low immunogenicity, biocompatibility, and biodegradability. tFNAs demonstrated promising results numerous vitro vivo applications.
Language: Английский
Citations
8