Nanotechnology’s frontier in combatting infectious and inflammatory diseases: prevention and treatment

Signal Transduction and Targeted Therapy, Journal Year: 2024, Volume and Issue: 9(1)

Published: Feb. 21, 2024

Abstract Inflammation-associated diseases encompass a range of infectious and non-infectious inflammatory diseases, which continuously pose one the most serious threats to human health, attributed factors such as emergence new pathogens, increasing drug resistance, changes in living environments lifestyles, aging population. Despite rapid advancements mechanistic research development for these current treatments often have limited efficacy notable side effects, necessitating more effective targeted anti-inflammatory therapies. In recent years, nanotechnology has provided crucial technological support prevention, treatment, detection inflammation-associated diseases. Various types nanoparticles (NPs) play significant roles, serving vaccine vehicles enhance immunogenicity carriers improve targeting bioavailability. NPs can also directly combat pathogens inflammation. addition, facilitated biosensors pathogen imaging techniques This review categorizes characterizes different NPs, summarizes their applications It discusses challenges associated with clinical translation this field explores latest developments prospects. conclusion, opens up possibilities comprehensive management

Language: Английский

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Gold nanoparticles in microelectronics advancements and biomedical applications

Materials Science and Engineering B, Journal Year: 2024, Volume and Issue: 301, P. 117191 - 117191

Published: Jan. 13, 2024

Language: Английский

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Nanostructures and nanoparticles as medical diagnostic imaging contrast agents: A review

Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 40, P. 102233 - 102233

Published: Aug. 5, 2024

Language: Английский

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A comprehensive review on recent progress in chitosan composite gels for biomedical uses

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 272, P. 132723 - 132723

Published: May 31, 2024

Language: Английский

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Recent Advances in Stimuli-Responsive Self-Immolative Polymers for Drug Delivery and Molecular Imaging

Chemistry of Materials, Journal Year: 2024, Volume and Issue: 36(9), P. 4054 - 4077

Published: April 18, 2024

Stimuli-responsive self-immolative polymers (SIPs) represent a unique class of that can undergo controlled, sequential head-to-tail depolymerization upon specific stimuli. Since their inception, they have evolved over two decades to become one the most attractive polymer types. With characteristic feature "one stimulus, multiple responses", SIPs inherently possess ability serve as chemical amplifiers, which amplify weak or biological signals. This promises higher stimulus sensitivity, greater selectivity for microenvironments, and potential generate more persistent, extensive, significant responses while consuming fewer stimuli sources. Review summarizes latest research advancements in stimuli-responsive drug delivery molecular imaging past five years. Regarding structure SIPs, we briefly overview updates self-immolation units, end-cap moieties, sequence SIPs. In terms applications, focus on possible applications disease treatment methods. Finally, provide brief perspective future directions these applications.

Language: Английский

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Advancements in Metal and Metal Oxide Nanoparticles for Targeted Cancer Therapy and Imaging: Mechanisms, Applications, and Safety Concerns

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106622 - 106622

Published: Jan. 1, 2025

Language: Английский

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Advanced Nanomaterials for Cancer Therapy: Gold, Silver, and Iron Oxide Nanoparticles in Oncological Applications

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 14(4)

Published: Nov. 6, 2024

Cancer remains one of the most challenging health issues globally, demanding innovative therapeutic approaches for effective treatment. Nanoparticles, particularly those composed gold, silver, and iron oxide, have emerged as promising candidates changing cancer therapy. This comprehensive review demonstrates landscape nanoparticle-based oncological interventions, focusing on remarkable advancements potentials oxide nanoparticles. Gold nanoparticles garnered significant attention their exceptional biocompatibility, tunable surface chemistry, distinctive optical properties, rendering them ideal various diagnostic strategies. Silver nanoparticles, renowned antimicrobial exhibit potential in therapy through multiple mechanisms, including apoptosis induction, angiogenesis inhibition, drug delivery enhancement. With magnetic properties offer unique diagnosis targeted opportunities. critically examines recent synthesis, functionalization, biomedical applications these Moreover, challenges are discussed, toxicity concerns, immunogenicity, translational barriers, ongoing efforts to overcome hurdles highlighted. Finally, insights into future directions regulatory considerations, provided aiming accelerate translation technologies from bench bedside.

Language: Английский

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Antibody Conjugates as CT/MRI Theranostics for Diagnosis of Cancers: A review of recent Trends and Advances

Sensors & Diagnostics, Journal Year: 2024, Volume and Issue: 3(9), P. 1428 - 1441

Published: Jan. 1, 2024

The constant need for cancer diagnosis in the early stages drives development of contrast agents and imaging methods.

Language: Английский

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Large-Scale Synthesis of Non-Ionic Bismuth Chelate for Computed Tomography Imaging in Vivo

Biomaterials, Journal Year: 2025, Volume and Issue: 318, P. 123122 - 123122

Published: Jan. 24, 2025

Language: Английский

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Recent advance on extracellular vesicle labeling: From strategy to probe

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 534, P. 216601 - 216601

Published: March 10, 2025

Language: Английский

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