Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2024, Volume and Issue: 703, P. 135176 - 135176
Published: Aug. 24, 2024
Language: Английский
ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 29, 2025
Coating biological membranes onto biomimetic nanocarriers improves biocompatibility, prolongs circulation, and enhances targeted delivery for cancer precision medicine. To better understand the biodistribution profiles of these nanosystems, molecular imaging techniques, including optical imaging, radionuclide magnetic resonance ultrasound have been widely employed in vivo tracking dynamic imaging. Here this review, we delve into profound role modalities visualizing changes tumor microenvironment, particularly monitoring oxygen consumption immune response dynamics, highlighting their potential to improve therapies. We also briefly discuss current applications synergistic therapies future perspectives. Finally, offer insights integrating nanomedicine with clinical translation.
Language: Английский
Citations
0
Polymer science & technology., Journal Year: 2025, Volume and Issue: unknown
Published: April 30, 2025
Language: Английский
Citations
0
Stem Cell Research & Therapy, Journal Year: 2025, Volume and Issue: 16(1)
Published: Feb. 4, 2025
Hair loss has long been a significant concern for many individuals. Recent studies have indicated that mitochondria play more crucial role in hair than previously recognized. This review summarizes the connection between mitochondrial dysfunction and follicle development, outlines links diseases related to disorders issues, highlights influence of on androgenetic alopecia. We discuss cellular signaling mechanisms associated with examine how dysfunction, such as insufficient energy supply, irregularities, protein/gene abnormalities, programmed cell death, can hinder normal proliferation, differentiation, growth cells. Furthermore, we current treatment approaches potential innovative therapies, including mitochondrion-targeting drugs advanced techniques directly target cells, providing fresh insights into maintaining health managing disorders. this explores future therapeutic strategies proposes research could lead groundbreaking treatments loss, thus optimism new avenues individuals experiencing loss. not only underscores central importance but also emphasizes advancing field.
Language: Английский
Citations
0
Regenerative Biomaterials, Journal Year: 2024, Volume and Issue: 11
Published: Jan. 1, 2024
In recent years, the regulation of cell microenvironment has opened up new avenues for bone defect repair. Researchers have developed novel biomaterials to influence behavior osteoblasts and immune cells by regulating microenvironment, aiming achieve efficient Mitochondria, as crucial organelles involved in energy conversion, biosynthesis signal transduction, play a vital role maintaining integrity. Dysfunction mitochondria can detrimental effects on transformation differentiation stem cells, thereby hindering tissue regeneration. Consequently, targeted therapy strategies focusing emerged. This approach offers wide range applications reliable therapeutic effects, providing treatment option complex refractory diseases. studies, more been used restore mitochondrial function promote positive differentiation. The main directions are metabolism, biogenesis quality control. this review, we investigated mitochondria-targeted repair years from perspective progress strategies. We also summarized micro-molecular mechanisms affected them. Through discussions oxidative stress autophagy regulation, emphasized opportunities challenges faced biomaterials, clues developing generation materials.
Language: Английский
Citations
3
Current Pharmaceutical Design, Journal Year: 2024, Volume and Issue: 30(10), P. 727 - 741
Published: March 1, 2024
Abstract: This review investigates the revolutionary application of cell membrane-coated nanoparticles (CMNPs) as a promising avenue for cancer therapy within embryonic landscape nanotechnology. Nanoparticles, pivotal in treatment, are systematically examined their diverse physicochemical structures, categorized organic (lipid-based, protein-based, and polymer-assisted) inorganic (carbon-based metal) varieties. A significant focus is placed on CMNPs, which serve an innovative drug delivery vehicle, overcoming limitations associated with conventional nanoparticle therapies. manuscript accurately explores advantages challenges various membranes, including those derived from cells, red blood platelets, stem white cells. Importance roles enhancing precision, immune system circumvention, targeted recognition. Detailed insights into crafting CMNPs provided, elucidating membrane extraction fusion techniques, such sonication, extrusion, co-extrusion, microfluidic electroporation. Maintaining integrity during benefits coating techniques augmenting biocompatibility underscored. comprehensive resource consolidates latest advancements delivery, positioning itself at forefront nanotechnology biomedicine research. Encapsulating methodologies like electrospray, chemical conjugation, this showcases expanding toolbox available to researchers dynamic field. Focusing unique characteristics multifaceted applications biomedical research, particularly tumour therapy. It provides indepth analysis stability, evasion capabilities, increased payload capacity, retained biological functionality. The outlines current future prospects chemotherapy, photothermal photodynamic therapy, immunotherapy, gene therapeutic methods. concludes by highlighting transformative potential reshaping treatment.
Language: Английский
Citations
2
Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2024, Volume and Issue: 703, P. 135176 - 135176
Published: Aug. 24, 2024
Language: Английский
Citations
1