Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Children with Obesity: An Obesity Medicine Association (OMA) and Expert Joint Perspective 2025

Obesity Pillars, Journal Year: 2025, Volume and Issue: 14, P. 100164 - 100164

Published: Feb. 1, 2025

This Obesity Medicine Association (OMA) Expert Joint Perspective examines steatotic liver disease (SLD), which is composed of metabolic dysfunction-associated (MASLD), and steatohepatitis (MASH) in children with obesity. The prevalence obesity increasing, rates have tripled since 1963 from 5 % to now 19 US affected 2018. MASLD, the most common seen children, can be a precursor development Type 2 Diabetes (T2DM) primary reason for transplant listing young adults. We must vigilant prevention treatment MASLD childhood prevent further progression. joint clinical perspective based upon scientific evidence, peer expertise. medical literature was reviewed via PubMed search appropriate articles were included this review. work formulated collaboration eight hepatologists/gastroenterologists expertise two physicians OMA. authors who are experts field, determined sentinel questions often asked by clinicians regarding They created consensus guideline on screening, diagnosis, associated children. comorbidity increasing problem that needs addressed urgently. It well known chronic continue these diseases as adults, leads reduced life expectancy, quality life, healthcare financial burden. paper recommend healthy weight reduction not only through lifestyle modification but pharmacotherapy bariatric surgery. Therefore, guidance reviews available therapies achieve reverse progressive fibrosis, disease.

Language: Английский

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Mediterranean Diet and Cardiometabolic Biomarkers in Children and Adolescents

JAMA Network Open, Journal Year: 2024, Volume and Issue: 7(7), P. e2421976 - e2421976

Published: July 12, 2024

No prior systematic review and meta-analysis has specifically verified the association of Mediterranean diet (MedDiet)-based interventions with biomarkers cardiometabolic health in children adolescents.

Language: Английский

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Adherence to the Mediterranean Diet in Children and Adolescents and Association with Multiple Outcomes: An Umbrella Review

Healthcare, Journal Year: 2024, Volume and Issue: 12(4), P. 449 - 449

Published: Feb. 9, 2024

The Mediterranean Diet (MD) has been linked to numerous health benefits. This umbrella review aims synthesize evidence from systematic reviews on the MD's impact children and adolescents aged 6 19 years. Following Joanna Briggs Institute guidelines, we included 11 focusing effects outcomes, such as asthma, anthropometric measures, physical fitness, inflammatory markers. results indicate a protective role of MD against childhood asthma due its antioxidant-rich components. However, for allergic conditions like rhinitis eczema is inconclusive. Findings regarding particularly BMI, are limited inconsistent. A positive correlation was observed between adherence increased activity, improved quality life, reduced sedentary behavior. Additionally, showed an inverse relationship with pro-inflammatory biomarkers, suggesting anti-inflammatory inconsistency in BMI findings potential properties warrant further longitudinal research. Future studies should explore cognitive functions, academic performance, mental this age group, highlighting significance establishing healthy eating habits early life.

Language: Английский

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Adherence to the Mediterranean diet in 5 Mediterranean countries: A descriptive analysis of the DELICIOUS project

Mediterranean Journal of Nutrition and Metabolism, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 10, 2024

Background: The Mediterranean diet is considered a healthy dietary pattern associated with substantial health benefits. While its application at global level rather difficult due to the intricate features eradicated into cultural heritage of populations living in countries facing basin, preservation such areas crucial maintain good status current and future generations. Objective: To assess adherence children adolescents 5 participating DELICIOUS project. Methods: An online survey was conducted involving 2011 parents from Spain, Italy, Lebanon, Egypt, Portugal. KIDMED score applied 24-h recalls their children's diets used cross-references background lifestyle variables. Results: Children Lebanon Portugal are more adherent than counterparts other countries. Some specific aspects related were common, as olive oil consumption, daily fruit vegetable intake, well habits including having breakfast limited sweets. Others, second portion vegetable, adequate consumption fish, nuts, cereals (for breakfast), frequent fast foods underscored abandonment certain features. Older inadequate sleep duration, longer screen time, low physical activity levels, older lower educational level, family income, rural had significantly scores. Conclusions: This study provides important information on among region may help setting targets for nutrition interventions aiming promotion.

Language: Английский

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The Benefits of the Mediterranean Diet on Inflamm-Aging in Childhood Obesity

Nutrients, Journal Year: 2024, Volume and Issue: 16(9), P. 1286 - 1286

Published: April 25, 2024

(1) Background: Numerous elements of the Mediterranean diet (MD) have antioxidant and anti-inflammatory qualities. (2) Methods: We present a narrative review potential benefits dietary pattern in mitigating aging-related inflammation (inflamm-aging) associated with childhood obesity. The mechanisms underlying chronic obesity are also discussed. A total 130 papers were included after screening abstracts full texts. (3) Results: complex interplay between obesity, inflammation, related comorbidities is documented. MD emerges as promising for inflammation. Studies suggest that may contribute to weight control, improved lipid profiles, insulin sensitivity, endothelial function, thereby reducing risk metabolic syndrome children adolescents (4) Conclusions: While evidence supporting effects pediatric still evolving, existing literature underscores its preventive therapeutic strategy. However, adherence remains low among adolescents, necessitating targeted interventions promote healthier habits. Future high-quality intervention studies necessary elucidate specific impact on diverse populations comorbidities.

Language: Английский

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Facilitators and barriers to healthful eating among adolescents in high‐income countries: A mixed‐methods systematic review

Obesity Reviews, Journal Year: 2024, Volume and Issue: 25(11)

Published: Aug. 15, 2024

Abstract Adolescent obesity continues to be a public health challenge with poor quality diets contributing its etiology. As part of the process plan promotion and policy interventions, understanding adolescents perceived facilitators barriers healthful eating is important. An integrative convergent mixed‐methods systematic review was used synthesize qualitative quantitative evidence from studies among aged 10–19 years in high‐income countries. Medline, Embase, PsycInfo, Scopus were searched for peer‐reviewed articles published between 2010 2023 exploring adolescents' perspectives on contemporary contextual factors. Transformed data integrated data. Text coded into subthemes themes using an inductive approach. Key included physical appearance; motivation; taste; nutrition knowledge, awareness, skills; education access; availability accessibility foods; family; social influences digital media. taste cravings unhealthful mood; lack motivation, high low cost peers influences; ineffective school policies; density fast‐food outlets; food advertising; time constraints. Social, behavioral, digital, environmental factors should considered adolescent perspective design education, promotion, interventions.

Language: Английский

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The ALINFA Intervention Improves Diet Quality and Nutritional Status in Children 6 to 12 Years Old

Nutrients, Journal Year: 2023, Volume and Issue: 15(10), P. 2375 - 2375

Published: May 18, 2023

The study aimed to evaluate the efficacy of a new nutritional intervention, focused on improving quality diet in children aged 6 12 years. A 2-month parallel, controlled randomized trial was conducted Spanish child population. were ALINFA which consisted normocaloric that incorporates products, ready-to-eat meals and healthy recipes specifically designed for study, or control group, received usual advice eating. change assessed through Kidmed index. secondary outcomes anthropometry, glucose lipid profiles, inflammation markers, dietary intake lifestyle. participants intervention group showed an increase mean score index (p < 0.001). Alongside that, these decreased their calories = 0.046), total saturated fat 0.016//p 0.011), increased fiber Likewise, white fish 0.001), pulses 0.004), whole grains 0.001) nuts fatty meat 0.014), refined grain 0.008), pastry fast food sugar intake. Moreover, had significantly BMI z-score waist circumference 0.016) mass as well leptin 0.004). Participants did not report significant changes quality. In conclusion, is possibly useful strategy children, associated improvements status. These results highlight importance developing well-designed interventions.

Language: Английский

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The Effect of a Program to Improve Adherence to the Mediterranean Diet on Cardiometabolic Parameters in 7034 Spanish Workers

Nutrients, Journal Year: 2024, Volume and Issue: 16(7), P. 1082 - 1082

Published: April 7, 2024

Background: Cardiovascular and metabolic diseases include a large group of pathologies constitute one the most serious chronic health problems facing 21st century, with high rates morbidity mortality worldwide. Unhealthy diets influence development these pathologies. The Mediterranean diet can be an important part in treatment diseases. objective this study was to assess effect program that aims increase adherence on improvement different cardiometabolic risk parameters. Methods: A prospective intervention carried out 7034 Spanish workers. Prior intervention, 22 scales were evaluated. Participants informed both orally writing characteristics benefits given website Ministry Health, Consumption Social Welfare Spain, which provides advice nutrition. Adherence reinforced by sending monthly SMS their mobile phones. After six months follow-up, re-evaluated changes. Means standard deviations calculated using Student’s t test analyse quantitative variables. Prevalence Chi-square when variables qualitative. Results: All studied decreased after implementing improve enhance diet. number losses sample very low, standing at 4.31%. Conclusions: is effective reducing all cardiovascular mean values prevalence analysed led lower implementation We observed significant positive difference age sexes. have obtained insulin resistance index, especially SPISE-IR data we not found previous publications. Easy access Internet new information communication technologies facilitate reduce losses.

Language: Английский

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A One-Week Elderberry Juice Intervention Augments the Fecal Microbiota and Suggests Improvement in Glucose Tolerance and Fat Oxidation in a Randomized Controlled Trial

Nutrients, Journal Year: 2024, Volume and Issue: 16(20), P. 3555 - 3555

Published: Oct. 20, 2024

Obesity is a costly and ongoing health complication in the United States globally. Bioactive-rich foods, especially those providing polyphenols, represent an emerging attractive strategy to address this issue. Berry-derived anthocyanins their metabolites are of particular interest for bioactive effects, including weight maintenance protection from metabolic aberrations. Earlier findings small clinical trials suggest modulation substrate oxidation glucose tolerance with mediation prospective benefits attributable gut microbiota, but mixed results appropriate anthocyanin dosing poses challenge. The objective randomized, placebo-controlled study was determine if anthocyanin-dense elderberry juice (EBJ) reproduces glucoregulatory effects observed other berries mediated by microbiota. Overweight or obese adults (BMI > 25 kg/m

Language: Английский

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The Interplay between Sleep Quality, Hedonic Hunger, and Adherence to the Mediterranean Diet among Early Adolescents

Appetite, Journal Year: 2025, Volume and Issue: 206, P. 107845 - 107845

Published: Jan. 2, 2025

Language: Английский

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