European Journal of Nutrition, Journal Year: 2024, Volume and Issue: 64(1)
Published: Nov. 23, 2024
Language: Английский
Nutrients, Journal Year: 2023, Volume and Issue: 15(14), P. 3204 - 3204
Published: July 19, 2023
Alzheimer's disease (AD) is a growing concern for the aging population worldwide. With no current cure or reliable treatments available AD, prevention an important and area of research. A range lifestyle dietary patterns have been studied to identify most effective preventive changes against AD related dementia (ADRD) pathology. Of these, are Mediterranean, DASH, MIND, ketogenic, modified Mediterranean-ketogenic diets. However, there discrepancies in reported benefits among studies examining these patterns. We herein compile narrative/literature review existing clinical evidence on association with ADRD symptomology contemplate their preventive/ameliorative effects neuropathology various milieus. By large, plant-based found be relatively consistently positively correlated preventing reducing odds ADRD. These impacts stem not only from direct impact specific components within brain but also indirect through decreasing deleterious risk factors, such as diabetes, obesity, cardiovascular diseases. Importantly, other psychosocial factors influence intake, social connection, which may directly diet lifestyle, thereby impacting risk. To this end, prospective research should include holistic approach, including considerations.
Language: Английский
Citations
46
Advances in Nutrition, Journal Year: 2024, Volume and Issue: 15(3), P. 100184 - 100184
Published: Feb. 3, 2024
The Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet seems a promising approach preserve brain function during aging. Previous systematic reviews have demonstrated benefits of the MIND cognition and dementia, though an update is needed. Additionally, other outcomes relevant aging not been summarized. Therefore, this review aims give up-to-date complete overview on human studies that examined in relation adults aged ≥40 y. Ovid Medline, Web Science core collection, Scopus were searched up July 25, 2023. Study quality was assessed using Newcastle-Ottawa Scale Cochrane Risk-of-Bias tool. We included 40 articles, which 32 unique cohorts. Higher adherence protective dementia 7 10 positive associations 3 4 cohorts global 6 episodic memory. effects cognitive decline are less apparent, with only 2 longitudinal demonstrating 1 memory decline. For (domain-specific cognition, impairments, Parkinson's disease, volume, pathology), results mixed or few had performed. Many North American origin, raising question if most favorable healthy population-dependent. In conclusion, provides observational evidence between risk, but remains and/or limited. may be preferred populations, populations conclusive. This registered at PROSPERO as CRD42022254625.
Language: Английский
Citations
22
British Journal Of Nutrition, Journal Year: 2024, Volume and Issue: 132(7), P. 898 - 918
Published: Oct. 14, 2024
Abstract An anti-inflammatory diet is characterised by incorporating foods with potential properties, including fruits, vegetables, whole grains, nuts, legumes, spices, herbs and plant-based protein. Concurrently, pro-inflammatory red processed meat, refined carbohydrates saturated fats are limited. This article explores the effects of an on non-communicable diseases (NCD), concentrating underlying mechanisms that connect systemic chronic inflammation, dietary choices disease outcomes. Chronic inflammation a pivotal contributor to initiation progression NCD. review provides overview intricate pathways through which influences pathogenesis conditions obesity, type II diabetes mellitus, CVD, autoinflammatory diseases, cancer cognitive disorders. Through comprehensive synthesis existing research, we aim identify some bioactive compounds present in deemed anti-inflammatory, explore their capacity modulate inflammatory and, consequently, prevent or manage The findings demonstrated herein contribute understanding interplay between nutrition, paving way for future recommendations research regarding preventive therapeutic strategies.
Language: Английский
Citations
11
The Journal of Prevention of Alzheimer s Disease, Journal Year: 2025, Volume and Issue: unknown, P. 100100 - 100100
Published: March 1, 2025
Dietary factors play a major role in cognitive aging, but few studies have assessed and compared the associations between specific dietary patterns Alzheimer's disease (AD) mortality. We included 27,773 U.S. participants (mean age = 59.8 years, 51.4 % female) from National Health Nutrition Examination Survey (NHANES) 1998 2016, with follow-up for AD mortality until December 2019. Five pattern scores were calculated utilizing one (1999-2002) or two repeated (2003-2016) 24hr recalls, including Healthy Eating Index (HEI-2015), healthful plant-based diet index (hPDI), alternate Mediterranean (aMED), Approach to Stop Hypertension (DASH), Mediterranean-DASH Intervention Neurodegeneration Delay (MIND) scores. utilized Cox proportional hazard models evaluate of these A total 260 deaths occurred during median 9.8 years. Higher aMED score was associated lower risk (HRT3vs T1: 0.72, 95 CI, 0.52-1.00, p-trend 0.041). In sub-sample 2,713 NHANES 2011-2014, 432 individuals had prevalent psychometric mild impairment (p-MCI). aMED, MIND, HEI-2015, hPDI odds p-MCI. The potential contributors higher intake levels vegetables nuts, moderate alcohol consumption, level sweets. more favorable outcomes among middle-aged older adults, underscoring importance healthy long-term benefits brain health.
Language: Английский
Citations
1
Diabetes Metabolic Syndrome and Obesity, Journal Year: 2023, Volume and Issue: Volume 16, P. 3353 - 3371
Published: Oct. 1, 2023
Purpose: Recent studies have expanded the scope of research on Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet beyond its impact cognitive performance. These investigations specifically explored potential to provide protection against cardiometabolic diseases and associated risk factors, including obesity dyslipidemia. Methods: We systematically summarized evaluated all existing observational trial evidence MIND in relation their factors adults. PubMed, Embase, CINAHL Cochrane Library databases were searched extract original humans published until September 2023, without date restrictions. A total 491 initially retrieved, out which 23 met eligibility criteria included final review. Duplicated irrelevant screened by five independent reviewers using Rayyan platform. Quality assessment was ascertained Newcastle-Ottawa scale risk-of-bias tool (RoB 2) randomized trials. Results: Across different study designs, generally with an improvement anthropometric measures other outcomes, such as blood pressure, glycemic control, lipid profile, inflammation stroke. The effects eating pattern some cardiovascular are less conclusive. Conclusion: findings this systematic review support recommendation a strategy reduce Further well-designed long-term warranted. Keywords: diet, dietary patterns, diseases,
Language: Английский
Citations
16
The journal of nutrition health & aging, Journal Year: 2024, Volume and Issue: 28(6), P. 100223 - 100223
Published: April 9, 2024
Previous studies suggested protective associations of vegetables and fruits (VF) intake with cognitive function, but evidence on specific types VF was insufficient. The current study included 4066 participants from 1997 to 2006 in the China Health Nutrition Survey (CHNS) 6170 2013 2020 Retirement Study (HRS). Dietary (using 3-day 24-h dietary recalls CHNS food frequency questionnaire HRS) function Telephone Interview for Cognitive Status-Modified, TICS-m) were measured. Linear mixed-effects models used estimate beta coefficients (β) 95% confidence intervals (CI) evaluate association (z-score) its decline. Highest total associated better slower Differences z-score between highest lowest tertiles consumption 0.039 (95% CI: 0.002, 0.076) 0.063 0.026, 0.100) HRS. corresponding differences annual decline 0.011 0.021) 0.012 0.003, 0.020) units respectively. Vegetables showed independent In subgroups, when comparing tertile intake, cruciferous (β = 0.058, 0.017, 0.100 β 0.067, 0.032, 0.101 green leafy 0.036, −0.001, 0.073 0.082, 0.046, 0.117 both cohorts. Similarly, higher dark-colored 0.019, 0.008, 0.030 red/yellow 0.004, 0.001, 0.007 subsequent years. Moreover, rigorous sensitivity analyses confirmed stability results. Our findings support potential beneficial roles VF, especially vegetables, maintaining slowing middle-aged older adults.
Language: Английский
Citations
6
Alzheimer s & Dementia, Journal Year: 2023, Volume and Issue: 20(2), P. 1190 - 1200
Published: Nov. 6, 2023
Abstract INTRODUCTION The associations of the Mediterranean‐DASH Intervention for Neurodegenerative Delay (MIND) diet with brain structural changes are unclear. METHODS Among 26,466 UK Biobank participants, a 15‐point MIND score was calculated from 24‐hour recalls 2009 to 2012. We assessed its 17 magnetic‐resonance‐derived volumetric markers and their longitudinal explored whether genetic factors modify associations. RESULTS Higher adherence associated larger volumes thalamus, putamen, pallidum, hippocampus, accumbens (beta per 3‐unit increment ranging 0.024 0.033) lower white matter hyperintensities ( P ‐trends < 0.05), regardless predispositions Alzheimer's disease. not > 0.05) over median 2.2 years among participants repeated imaging assessments N = 2963), but slower atrophy in putamen (beta: 0.026, ‐trend 0.044) pallidum 0.030, APOE ε4 non‐carriers 654). DISCUSSION showed beneficial certain markers, long‐term warrants future investigation. Highlights Adherence significantly higher gray regions adults, were modified by factors. No significant observed between investigated years. non‐carriers.
Language: Английский
Citations
11
Neurology, Journal Year: 2024, Volume and Issue: 103(8)
Published: Sept. 18, 2024
Diet may influence the development of cognitive impairment and affect decline, but whether this relationship varies between Black American White people is unclear. This study examined association Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) incident trajectories in a biracial prospective cohort study.
Language: Английский
Citations
4
Nature Reviews Neurology, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 21, 2024
Language: Английский
Citations
4
Journal of Alzheimer s Disease Reports, Journal Year: 2025, Volume and Issue: 9
Published: Jan. 1, 2025
Background In contrast to existing evidence focusing on high-income countries, this study offers novel insights into the demographic and geographical context that have yet be explored in literature. Comparatively, Pakistan, cognitive impairment is one of neglected disorders can develop dementia Alzheimer's disease. As no treatment available, lifestyle modifications are a valid intervention for health. Objective This aimed assess relationship between physical functionality, adherence Mediterranean-DASH diet Intervention Neurological Delay (MIND), among elderly individuals Pakistan. Methods From January June 2023, cross-sectional recruited 462 participants aged 65 above. We used proven tools gerontological research, such as MIND quiz Quick Physical Activity Rating scale (QPAR), evaluate activity levels. Cognitive function was assessed using Mini-Mental State Examination. Results Our analysis revealed 26.40% had mild impairment, whereas 48.50% demonstrated low diet. The mean QPAR score 20.51 ± 18.77. A significant association found lower levels increased (adjusted odds ratio 9.94, confidence interval (CI): 6.07–16.27). Additionally, higher correlated with reduced (odds 0.29, CI: 0.18–0.46). Conclusions These findings highlight critical role health population. emphasizes need targeted public interventions further longitudinal research explore long-term effects these factors
Language: Английский
Citations
0