American Journal of Reproductive Immunology,
Journal Year:
2020,
Volume and Issue:
84(5)
Published: July 17, 2020
Coronavirus
disease
2019
or
COVID-19
is
an
emerging
viral
caused
by
a
member
of
the
betacoronavirus
family,
SARS-CoV-2.
Since
its'
emergence
in
December
2019,
it
has
rapidly
close
to
half
million
fatalities
globally.
Data
regarding
impact
on
pregnancy
are
limited.
Here,
we
review
pathological
findings
placentas
from
women
who
tested
positive
for
SARS-CoV-2
as
well
information
outcomes
associated
with
related
and
highly
pathogenic
coronaviruses
(ie,
severe
acute
respiratory
syndrome
(SARS-COV)
Middle
East
syndrome,
MERS).
We
present
immune-inflammatory
correlates
role
Renin
Angiotensin
System
pathogenesis
pregnancy.
Greater
understanding
placenta
will
yield
important
insight
into
potential
therapeutic
interventions
pregnant
COVID-19.
Applied Organometallic Chemistry,
Journal Year:
2024,
Volume and Issue:
38(7)
Published: May 21, 2024
The
antimicrobial
properties
of
copper
ions
can
reduce
the
overgrowth
microorganisms
to
a
certain
extent.
That
reduces
amount
antibiotics
used,
avoid
superbugs
and
potential
harm.
authors
reviewed
mechanisms
copper‐containing
nanoparticles
(NPs),
focusing
on
factors
influencing
their
properties.
They
concluded
that
were
better
in
environments
conducive
precipitation
exposure
microorganisms.
Comparing
with
other
metal
leads
question
why
is
such
an
important
ion.
In
recent
years,
development
science
technology
understanding
microscopic
world,
scientists
have
skillfully
applied
various
settings,
from
direct
contact
food
breeding
hygienic
environments,
confirmed
safety
application.
However,
because
toxic
effect
NPs,
future
goal
synthesize
NP
good
biocompatibility
antibacterial
efficiency
benefit
human
society.
Nature Communications,
Journal Year:
2025,
Volume and Issue:
16(1)
Published: March 1, 2025
Prenatal
exposure
to
metals
has
been
associated
with
impaired
neurodevelopment
in
children,
but
the
detailed
molecular
mechanisms
remain
largely
unknown.
Based
on
Wuhan
Healthy
Baby
Cohort,
China
(N
=
1088),
eleven
were
measured
maternal
urine
during
early
pregnancy
(13.1
±
1.1
weeks)
and
metabolomics
profiling
was
conducted
cord
blood.
Neurodevelopment
evaluated
using
Bayley
Scales
of
Infant
Development
2-year-old
children
obtain
mental
development
index
(MDI)
psychomotor
(PDI).
After
false
discovery
rate
correction,
higher
urinary
levels
manganese,
nickel,
aluminum,
rubidium,
gallium,
summary
score
only
significantly
lower
MDI
scores.
The
weighted
quantile
sum
metal
mixture
showed
a
significant
inverse
association
PDI
scores,
aluminum
contributing
most
associations.
Histidine,
beta-alanine,
purine,
pyrimidine
metabolism
mediated
above
associations,
suggesting
that
disturbances
amino
acids,
neurotransmitter
neuroendocrine
may
be
important
mediators
children.
linked
underlying
are
unclear.
Here,
authors
show
neurotransmitters,
mediate
association.
Science,
Journal Year:
2020,
Volume and Issue:
368(6491), P. 608 - 612
Published: May 7, 2020
Viral
infections
during
pregnancy
can
have
devastating
consequences
on
outcomes,
fetal
development,
and
maternal
health.
In
this
review,
we
examine
immune
defense
mechanisms
that
mediate
resistance
against
viral
discuss
the
range
of
syndromes
ensue
when
such
fail,
from
developmental
defects
to
establishment
chronic
infection.
Further,
highlight
role
activation,
or
uncontrolled
inflammation
triggered
by
pregnancy,
its
potential
downstream
pathological
effects,
including
tissue
damage
demise.
Insights
into
respective
contributions
direct
toxicity
versus
responses
underlie
pathogenesis
congenital
disease
will
guide
future
treatment
strategies.
American Journal of Reproductive Immunology,
Journal Year:
2020,
Volume and Issue:
84(5)
Published: July 17, 2020
Coronavirus
disease
2019
or
COVID-19
is
an
emerging
viral
caused
by
a
member
of
the
betacoronavirus
family,
SARS-CoV-2.
Since
its'
emergence
in
December
2019,
it
has
rapidly
close
to
half
million
fatalities
globally.
Data
regarding
impact
on
pregnancy
are
limited.
Here,
we
review
pathological
findings
placentas
from
women
who
tested
positive
for
SARS-CoV-2
as
well
information
outcomes
associated
with
related
and
highly
pathogenic
coronaviruses
(ie,
severe
acute
respiratory
syndrome
(SARS-COV)
Middle
East
syndrome,
MERS).
We
present
immune-inflammatory
correlates
role
Renin
Angiotensin
System
pathogenesis
pregnancy.
Greater
understanding
placenta
will
yield
important
insight
into
potential
therapeutic
interventions
pregnant
COVID-19.
