Regulation of Microalgal Photosynthetic Electron Transfer DOI Creative Commons
Yuval Milrad, Laura Mosebach, Félix Buchert

et al.

Plants, Journal Year: 2024, Volume and Issue: 13(15), P. 2103 - 2103

Published: July 29, 2024

The global ecosystem relies on the metabolism of photosynthetic organisms, featuring ability to harness light as an energy source. most successful type photosynthesis utilizes a virtually inexhaustible electron pool from water, but driver this oxidation, sunlight, varies time and intensity scales several orders magnitude. Such rapid steep changes in availability are potentially devastating for biological systems. To enable safe efficient light-harnessing process, organisms tune their capturing, redox connections between core complexes auxiliary mediators, ion passages across membrane, functional coupling transducing organelles. Here, microalgal species diverse group, both unique environmental adjustment strategies ubiquitous protective mechanisms. In review, we explore selection regulatory processes apparatus supporting smooth flow variable environments.

Language: Английский

Immunomodulatory Compounds from the Sea: From the Origins to a Modern Marine Pharmacopoeia DOI Creative Commons
Edoardo Andrea Cutolo, Rosanna Campitiello, Roberto Caferri

et al.

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(7), P. 304 - 304

Published: June 28, 2024

From sea shores to the abysses of deep ocean, marine ecosystems have provided humanity with valuable medicinal resources. The use organisms is discussed in ancient pharmacopoeias different times and geographic regions still deeply rooted traditional medicine. Thanks present-day, large-scale bioprospecting rigorous screening for bioactive metabolites, ocean coming back as an untapped resource natural compounds therapeutic potential. This renewed interest drugs propelled by a burgeoning research field investigating molecular mechanisms which newly identified intervene pathophysiology human diseases. Of great clinical relevance are molecules endowed anti-inflammatory immunomodulatory properties emerging applications management chronic inflammatory disorders, autoimmune diseases, cancer. Here, we review historical development pharmacology Eastern Western worlds describe status drug discovery. Finally, discuss importance conducting sustainable exploitation resources through biotechnology.

Language: Английский

Citations

4
Analysis of the effect of fertilization with biomass of selected aquatic algae on soil sorption parameters DOI Creative Commons
Ewa Stańczyk-Mazanek

Desalination and Water Treatment, Journal Year: 2025, Volume and Issue: unknown, P. 101183 - 101183

Published: April 1, 2025

Language: Английский

Citations

0
Genetic engineering of Nannochloropsis oceanica to produce canthaxanthin and ketocarotenoids DOI Creative Commons

Davide Canini,

Flávio Martini, Stefano Cazzaniga

et al.

Microbial Cell Factories, Journal Year: 2024, Volume and Issue: 23(1)

Published: Nov. 29, 2024

Abstract Background Canthaxanthin is a ketocarotenoid with high antioxidant activity, and it primarily produced by microalgae, among which Nannochloropsis oceanica , marine alga widely used for aquaculture. In the last decade, N. has become model organism oleaginous microalgae to develop sustainable processes produce biomolecules of interest exploiting its photosynthetic activity carbon assimilation properties. can accumulate lipids up 70% total dry weight contains omega-3 fatty acid eicosapentaenoic (EPA) required both food feed applications. The genome sequence, other omics data, synthetic biology tools are available this species, including an engineered strain called LP-tdTomato, allows homologous recombination insert heterologous genes in highly transcribed locus nucleolus region. Here, was induce canthaxanthin production. Results We LP-tdTomato as background express key enzyme production, β-carotene ketolase (CrBKT) from Chlamydomonas reinhardtii . Through strain, transgene insertion genomic be screened negative fluorescence. overexpression CrBKT bkt transformants increased content carotenoids ketocarotenoids per cell, respectively, 1.5 10-fold, inducing orange/red color cell cultures. ( LP ) lines productivity were compared at different light intensities 150 1200 µmol m -2 s -1 : lower irradiances, growth kinetics slower while higher measured Despite these results, highest obtained upon cultivation Conclusions targeted gene redesign transformation, significantly increased, achieving 0.3% 0.2% weight. could using CO 2 only source mg/L titer. These bkt-engineered hold potential industrial applications fish or poultry sectors, where pigmentation agents.

Language: Английский

Citations

3
Isolation and identification of thermophilic cyanobacterium inhabiting Shiv Kund (Sohna hot spring), India through polyphasic approach: Bioprospecting in varying nitrogen environment for biotechnological interest particularly for biofuel potential DOI

Neha Saini,

Sharma Mona

Algal Research, Journal Year: 2024, Volume and Issue: unknown, P. 103757 - 103757

Published: Oct. 1, 2024

Language: Английский

Citations

1
Regulation of Microalgal Photosynthetic Electron Transfer DOI Creative Commons
Yuval Milrad, Laura Mosebach, Félix Buchert

et al.

Plants, Journal Year: 2024, Volume and Issue: 13(15), P. 2103 - 2103

Published: July 29, 2024

The global ecosystem relies on the metabolism of photosynthetic organisms, featuring ability to harness light as an energy source. most successful type photosynthesis utilizes a virtually inexhaustible electron pool from water, but driver this oxidation, sunlight, varies time and intensity scales several orders magnitude. Such rapid steep changes in availability are potentially devastating for biological systems. To enable safe efficient light-harnessing process, organisms tune their capturing, redox connections between core complexes auxiliary mediators, ion passages across membrane, functional coupling transducing organelles. Here, microalgal species diverse group, both unique environmental adjustment strategies ubiquitous protective mechanisms. In review, we explore selection regulatory processes apparatus supporting smooth flow variable environments.

Language: Английский

Citations

0