American Journal on Addictions,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 5, 2024
Abstract
Background
and
Objectives
Prenatal
cannabis
use
prevalence
in
the
United
States
has
increased.
Relaxation
of
state‐level
policy
may
be
contributing
to
diminished
risk
perception
using
cannabis.
The
main
psychoactive
constituent
cannabis,
delta‐9‐tetrahydrocannabinol,
crosses
placenta,
interacting
with
functional
cannabinoid
receptors
fetus.
Here,
we
assess
association
between
prenatal
exposure
(PCE)
a
set
birth
outcomes.
Methods
Using
Michigan
Archive
for
Research
on
Child
Health,
prospective
pregnancy
cohort,
linked
survey
data
neonatal
from
state‐archived
records.
Recruitment
occurred
23
clinics
across
Michigan.
Pregnant
participants
live
records
October
2017
January
2022,
after
exclusion
missing
use,
outcomes,
covariates,
were
included
final
analytic
sample
(
n
=
584).
Analyses
involved
generalized
linear
models.
Results
An
estimated
15%
(95%
confidence
interval
[CI]:
12%,
18%)
reported
during
pregnancy.
Covariate‐adjusted
models
revealed
an
PCE
size
ß
−0.3;
95%
CI:
−0.5,
−0.003).
Discussion
Conclusions
Findings
suggest
relationship
smaller
size.
Clinicians
should
follow
guidelines
outlined
by
American
College
Obstetricians
Gynecologists
when
counseling
pregnant
patients
use.
Scientific
Significance
We
detected
significant
Most
studies
focus
only
extremes
size,
however,
z
‐scores
allow
assessment
sex‐specific
weight‐for‐gestational
age
distribution,
increasing
accuracy
detecting
effect
Obstetrics and Gynecology,
Journal Year:
2023,
Volume and Issue:
unknown
Published: Aug. 10, 2023
OBJECTIVE:
To
understand
pregnant
patients'
reasons
for
prenatal
cannabis
use
and
perceptions
of
safety,
desired
undesirable
health
care
experiences,
information
about
secondarily
to
racial
differences
in
these
preferences.
METHODS:
We
conducted
a
qualitative
study
including
18
semi-structured,
race-concordant
virtual
focus
groups
with
individuals
who
self-reported
at
entry
large
integrated
system
Northern
California
from
November
2021
December
2021.
The
included
semi-structured
questions
that
were
recorded,
transcribed,
coded
by
the
research
team.
Thematic
analysis
was
used
analyze
data.
RESULTS:
Overall,
53
participants
included;
30
self-identified,
as
White
23
self-identified
Black.
Participants
averaged
30.3
years
age
(SD
5.2
years)
on
average
20.9
weeks
gestation
enrollment;
69.8%
reported
daily
use,
24.5%
weekly
5.7%
monthly
or
less
entrance
care.
Although
some
quit
early
pregnancy
because
concerns
potential
risks,
many
perceived
lack
scientific
evidence
believed
safe.
Many
preferred
over-the-counter
prescription
medications
treating
mood,
morning
sickness,
pain,
sleep.
valued
open
interactions
obstetricians
acknowledged
their
motivations
they
risks
through
conversations
educational
materials.
Black
participants'
perspectives
generally
similar,
but
few
uniquely
described
bias
related
use.
CONCLUSION:
Pregnant
patients
manage
mood
medical
symptoms,
safer
than
medications.
Obstetrician-initiated,
patient-centered
around
advice
discontinue
during
pregnancy,
exploration
willingness
switch
medically
recommended
interventions
pregnancy-related
symptoms
may
benefit
patients.
Obstetrics and Gynecology,
Journal Year:
2024,
Volume and Issue:
144(4), P. e101 - e104
Published: Aug. 30, 2024
This
population-based
cross-sectional
study
analyzed
electronic
health
record
data
of
pregnant
individuals
in
an
integrated
care
delivery
system
California
to
examine
changes
prenatal
cannabis
use
through
self-report
and
urine
toxicology
testing
during
standard
between
2012
(n=33,546)
2022
(n=43,415),
test
whether
trends
differed
by
race
ethnicity
or
age.
The
prevalence
increased
from
5.5%
(95%
CI,
5.3–5.8%)
9.0%
8.7–9.2%)
(adjusted
ratio
[aPR]
1.82,
95%
1.72–1.92),
with
similar
increases
(aPR
1.70,
1.60–1.81)
2.12,
1.95–2.30).
increase
varied
significantly
across
racial
ethnic
age
groups,
the
highest
among
Black
those
aged
13–24
years.
Although
rates
more
slowly
groups
use,
disparities
persisted
over
time.
Advances in Nutrition,
Journal Year:
2024,
Volume and Issue:
15(4), P. 100196 - 100196
Published: March 1, 2024
Cannabis
use
has
increased
sharply
in
the
last
20
years
among
adults,
including
reproductive-aged
women.
Its
recent
widespread
legalization
is
associated
with
a
decrease
risk
perception
of
cannabis
during
breastfeeding.
However,
effect
(if
any)
on
milk
production
and
composition
not
known.
This
narrative
review
summarizes
current
knowledge
related
to
maternal
breastfeeding
provides
an
overview
possible
pathways
whereby
might
affect
production.
Several
studies
have
demonstrated
that
cannabinoids
their
metabolites
are
detectable
human
produced
by
mothers
who
cannabis.
Due
physicochemical
properties,
stored
adipose
tissue,
can
easily
reach
mammary
gland,
be
secreted
milk.
Moreover,
cannabinoid
receptors
present
adipocytes
epithelial
cells.
The
activation
these
directly
modulates
fatty
acid
metabolism,
potentially
causing
changes
profiles.
Additionally,
endocannabinoid
system
(ECS)
intimately
connected
endocrine
system.
As
such,
it
probable
interactions
exogenous
ECS
modify
release
critical
hormones
(e.g.,
prolactin
dopamine)
regulate
secretion.
Nonetheless,
few
investigated
effects
(including
composition)
lactating
Additional
research
utilizing
robust
methodologies
needed
elucidate
whether
how
affects
composition.
To
our
knowledge,
no
focused
potential
evidence
provided
herein
supports
possibility
that,
through
several
well
documented
pathways,
alter
lipid
metabolism
as
Considering
increase
women,
this
highlights
need
for
designed,
address
question.
The Canadian Journal of Psychiatry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 14, 2024
Objectives
Cannabis
legalization
has
triggered
an
increase
in
prenatal
cannabis
use.
Given
that
tobacco
is
commonly
co-used
with
cannabis,
determining
outcomes
associated
and
co-exposure
crucial.
While
literature
exists
regarding
the
individual
effects
of
exposure
on
childhood
behaviour,
there
a
gap
their
combined
use,
which
may
have
interactive
effects.
Therefore,
we
investigated
whether
was
greater
externalizing
internalizing
problems
middle
compared
to
either
substance
alone
or
no
exposure.
Methods
Baseline
data
from
Adolescent
Brain
Cognitive
Development
(ABCD)
Study
(collected
children
ages
9–11)
were
used
explore
differences
scores
derived
Childhood
Behavior
Checklist
across
four
groups:
(CT,
n
=
290),
cannabis-only
(CAN,
225),
tobacco-only
(TOB,
966),
unexposed
(CTL,
8,311).
We
also
examined
if
daily
quantity
modulated
effect
outcomes.
Results
Adjusting
for
covariates,
2
×
ANCOVA
revealed
significant
main
(
p
0.03)
<
0.001),
interaction
0.032);
interactions
found
scores.
However,
between
significantly
predicted
both
0.01).
Conclusions
These
findings
indicate
than
alone,
did
not
differ
each
other.
Further,
amplify
negative
behaviours
children.
underscore
need
interventions
target
co-use
pregnant
women
circumvent
adverse
impact
behaviour.
Nutrition in Clinical Practice,
Journal Year:
2023,
Volume and Issue:
39(2), P. 281 - 292
Published: Dec. 23, 2023
Abstract
In
recent
years,
the
legalization
and
social
acceptability
of
cannabis
use
have
increased
in
United
States.
Concurrently,
prevalence
has
continued
to
rise,
products
diversified.
There
are
growing
concerns
regarding
health
effects
regular
high‐potency
use,
new
research
shed
light
on
its
potentially
negative
effects.
Here,
we
review
evidence
gastrointestinal
(GI)
cannabinoids.
Dysregulation
endocannabinoid
system
might
contribute
various
GI
disorders,
including
irritable
bowel
syndrome
cyclic
vomiting
syndrome,
endocannabinoids
been
found
regulate
visceral
sensation,
nausea,
vomiting,
gut
microbiome.
Cannabis
shown
antiemetic
properties,
US
Food
Drug
Administration
approved
cannabis‐based
medications
for
treating
chemotherapy‐induced
nausea
vomiting.
Yet,
chronic
heavy
linked
recurrent
episodes
severe
intractable
(cannabinoid
hyperemesis
syndrome).
Given
considerable
heterogeneity
scientific
literature,
it
is
unclear
if
cannabinoid
truly
a
distinct
entity
or
subtype
that
unmasked
by
associated
dysregulation
system.
The
changes
legalization,
availability,
public
risk
perceptions
outpaced
this
area
there
need
robust,
prospective,
large‐scale
studies
understand
health.
Substance Use & Misuse,
Journal Year:
2023,
Volume and Issue:
59(5), P. 690 - 698
Published: Dec. 22, 2023
Background
Marijuana
is
the
most
commonly
used
federally
illicit
substance
among
reproductive-age
women
in
United
States.
Updated
information
on
marijuana
use
this
population
can
inform
clinical
and
public
health
interventions.
Journal of the Academy of Consultation-Liaison Psychiatry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 1, 2024
Psychiatric
illness
during
pregnancy
is
associated
with
adverse
obstetric
outcomes,
but
investigations
into
its
impact
on
parenting
capacity
are
limited.
Child
Protective
Services
(CPS)
contact
disproportionately
impacts
families
marginalized
by
poverty,
mental
health
disorders,
and
substance
use
disorders.
Recently,
there
have
been
the
significance
of
psychiatric
nonmental
health-related
factors
that
predict
CPS
custody
arrangements.
To
identify
clinical
newborns'
under
for
mothers
antenatal
hospitalization.
We
conducted
a
retrospective
review
electronic
medical
records
over
10-year
period
(2012–2021)
patients
who
were
pregnant
their
inpatient
hospitalizations.
followed
81
(18
to
43
years
old)
delivered
within
hospital.
The
study
endpoint
was
whether
newborn
placed
custody.
For
purposes
this
study,
categorized
presence
or
absence
psychotic
symptoms.
utilized
logistic
regressions
investigate
associations
these
demographic
outcome
entire
population,
64.2%
newborns
had
In
multivariate
analysis,
after
adjusting
potential
confounders,
symptoms
at
increased
odds
having
arrangements
(odds
ratio
=
8.43;
95%
confidence
interval
2.16-32.85)
compared
without
Furthermore,
analyses
revealed
history
homelessness
also
higher
risk
6.59;
interval:
1.24-35.13)
than
those
homelessness.
results
suggest
among
psychiatrically
hospitalized
patients,
significantly
more
likely
However,
it
important
note
not
definitive
inability
parent
appropriately.
fact,
nearly
25%
population
able
successfully
transition
home
as
mothers.
This
emphasizes
importance
optimizing
management
symptoms,
particularly
children
plan
children.
findings
highlight
chronic
struggled
may
experience,
including
resolves.
