Terpinen-4-ol Improves the Intestinal Barrier Function of the Colon in Immune-Stressed Weaning Piglets DOI Creative Commons

YU Lihuai,

Guangzhi Qiu,

Xiaoping Yu

et al.

Animals, Journal Year: 2024, Volume and Issue: 15(1), P. 9 - 9

Published: Dec. 24, 2024

The aim of this study was to investigate the effects terpinen-4-ol (TER) supplementation on intestinal barrier function pigs. Five groups fifty 28-day-old piglets with comparable body weights were randomly assigned following groups: control group (CON), lipopolysaccharide (LPS), low TER (PLT), middle (PMT), and high (PHT). basal diet given CON LPS groups, 30, 60, or 90 mg/kg added for groups. After 21-day trial period, in received an intraperitoneal injection 100 μg/kg weight LPS, whereas 0.9% normal saline solution. results showed that stimulation resulted a decrease (p < 0.05) depth colonic crypts piglets, which greater group. Compared those group, number goblet cells MUC2 expression decreased colon while these parameters increased PMT 0.05). malondialdehyde (MDA) content than activities glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), catalase (CAT) lower group; conversely, MDA colons PLT also reduced LPS-induced upregulation IL-1β TNF-α expression, along relative gene NLRP3, ASC, caspase-1 abundances Firmicutes UCG-005 0.05), significantly abundance Proteobacteria Actinobacteria Phascolarctobacterium PHT compared In conclusion, effectively improved weaning piglets. Based study, appropriate dose diets 60 mg/kg.

Language: Английский

Efficacy of combined therapy with fenbendazole and Bacillus amyloliquefaciens in treating strongylatosis in horses DOI Creative Commons

O. V. Demkina

Russian Journal of Parasitology, Journal Year: 2025, Volume and Issue: 19(1), P. 108 - 117

Published: March 18, 2025

The purpose of the research is to evaluate efficacy combined use fenbendazole and Bacillus amyloliquefaciens against Strongylata in horses, compare therapy monotherapy, study effect on general clinical state horses. Materials methods . was conducted 20 horses divided into two groups 10 animals. from experimental group were given once at a dose 7.5 mg/kg, probiotic B. daily 50 mg/kg for 14 days. control received only fenbendazole. monitored by examining faeces using flotation method days 7, 10, 14, 16, 19, 22, 25, 28, 31, 34 after treatment. On day experiment, test reduction rates number eggs calculated. To determine starting dates repeated egg release, values obtained 7 used. Faecal microbiota analyzed before treatment 14. Results discussion Both showed with gradual increase their experiment. first detected therapy. period release weeks groups. Test below 90% both faecal did not reveal significant changes probiotic, although Aspergillus fungi disappeared Throughout study, remained clinically healthy no signs gastrointestinal disorders. result any statistically deworming as compared alone (P > 0.05). However, anthelmintic certain biological advantage expressed decrease group. Despite lack intestinal microbiota, absence spp. administered may indicate its potential antifungal effect.

Language: Английский

Citations

0

Dietary Angelica sinensis Enhances Sow Lactation and Piglet Development Through Gut Microbiota and Metabolism DOI Creative Commons
Qian Chen,

Yali Song,

Qinghua Wu

et al.

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(4), P. 370 - 370

Published: April 15, 2025

Piglets weaned per sow year (PSY) is a crucial metric for assessing the reproductive performances of sows and directly affects both productivity economic profitability pig farms [...]

Language: Английский

Citations

0

Progress in Fermented Unconventional Feed Application in Monogastric Animal Production in China DOI Creative Commons
Haoxuan Sun,

Xinyue Kang,

Huize Tan

et al.

Fermentation, Journal Year: 2023, Volume and Issue: 9(11), P. 947 - 947

Published: Nov. 1, 2023

Unconventional animal feeds present distinct features and considerable variations. However, their efficacy in monogastric animals is hindered by high levels of anti-nutritional elements subpar palatability. Feed fermentation could offer a solution to these issues. Moreover, fermented unconventional deliver notable economic advantages represent viable alternative antibiotic growth promoters, particularly the context restrictions, promising potential. This review provides an in-depth exploration types, characteristics, processes, application outcomes, associated challenges, prospects animals. We anticipate that this comprehensive overview will serve as valuable reference for developing utilizing feed resources industry.

Language: Английский

Citations

7

Effects of baicalin and chlorogenic acid on growth performance, slaughter performance, antioxidant capacity, immune function and intestinal health of broilers DOI Creative Commons
Xingbo Liu,

Yunru Ji,

Zhiguo Miao

et al.

Poultry Science, Journal Year: 2024, Volume and Issue: 103(11), P. 104251 - 104251

Published: Aug. 23, 2024

Language: Английский

Citations

2

Bacillus spp. as potential probiotics: promoting piglet growth by improving intestinal health DOI Creative Commons
Xiaopeng Tang, Yan Zeng, Kangning Xiong

et al.

Frontiers in Veterinary Science, Journal Year: 2024, Volume and Issue: 11

Published: July 26, 2024

The application of

Language: Английский

Citations

2

Screening and Characterization of Probiotics Isolated from Traditional Fermented Products of Ethnic-Minorities in Northwest China and Evaluation Replacing Antibiotics Breeding Effect in Broiler DOI Creative Commons
Ze Ye, Bin Ji, Yinan Peng

et al.

Polish Journal of Microbiology, Journal Year: 2024, Volume and Issue: 73(3), P. 275 - 295

Published: Aug. 25, 2024

In this study,

Language: Английский

Citations

2

Effects of fermented unconventional protein feed on pig production in China DOI Creative Commons
Haoxuan Sun, Zipeng Jiang, Zhimin Chen

et al.

Frontiers in Veterinary Science, Journal Year: 2024, Volume and Issue: 11

Published: July 31, 2024

Unconventional protein feeds, characterized by low nutritional value, high variability, and poor palatability, have limited their application in swine production. Fermentation technology holds the key to addressing these shortcomings. Given ban on antibiotics China, inferior quality of imported pig breeds, long-term dependence soybean, prospects for fermented unconventional feeds are promising. This paper delves into common types factors influencing fermentation process, mechanisms which they enhance health, challenges offering theoretical insights future development feed industry.

Language: Английский

Citations

1

Development and immunogenicity evaluation of attenuated Salmonella typhimurium delivering porcine Deltacoronavirus S1 gene DOI
Junpeng Yang, Rui Chen, Mengke Sun

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138615 - 138615

Published: Dec. 1, 2024

Language: Английский

Citations

1

Bacillus siamensis Improves the Immune Status and Intestinal Health of Weaned Piglets by Improving Their Intestinal Microbiota DOI Creative Commons

Huawei Liu,

Xinyu Liu,

Haiyang Liu

et al.

Microorganisms, Journal Year: 2024, Volume and Issue: 12(5), P. 1012 - 1012

Published: May 17, 2024

Previous studies on the early interference of gut microbiota by Bacillus siamensis (B. siamensis) in weaned piglets are rarely reported, and present trial is a preliminary study. This experiment was conducted to investigate effects B. supplementation growth performance, serum biochemistry, immune response, fecal short-chain fatty acids piglets. Sixty were randomly divided into control group (CON) (BS), which fed basal diet supplemented with 5 × 1010 CFU per kg, respectively. Each had 3 replicates 10 replicate. The lasted for 28 days. results showed that significantly increased hormone (GH) insulin-like factor (IGF) Compared CON group, levels immunoglobulin inflammatory factors BS improved. In addition, concentrations zonulin endotoxin (ET) lower. dietary addition acid (SCFA) Notably, improved microbial composition increasing beneficial genera, including Weissella, Lachnospiraceae_NK4A136_group Bifidobacterium, decreasing pathogenic Pantoea, Fusobacterium Gemella, piglet feces. Correlation analysis benefits closely related its composition. summary, can improve immunity function, permeability SCFA piglets, may be achieved through improvement their microbiota.

Language: Английский

Citations

0

Concentration of α-Glycerol Monolaurate and Tributyrate Glyceryl and Their Ratio Affected Growth Performance, Gut Microbiota and Immune Function of Weaned Piglets DOI
Shuang Dong, Nan Zhang, Shuyu Peng

et al.

Published: Jan. 1, 2024

The aim of this study was to investigate the effects concentrations and ratios α-glycerol monolaurate (GML) tributyrate glyceryl (TB) on growth performance, gut microbiota immune function in weaned piglets explore ideal model medium short chain fatty acids (MSCFA). In Exp 1, 120 (Duroc × [ Landrace Yorkshire], average weight 6.88 kg) were randomly assigned three treatments with five replicates (eight per replicate pen) treatment based BW sex optimal concentration MSCFA. 1) CON: a basal diet; 2) T1: diet 0.5% GML + TB; 3) T2: 1.0% TB. Based TB determined Exp1, 2 designed ratio T3: 0.7% 0.3%TB; T4: 0.3% these experiments, there no difference daily gain, feed intake, or conversion ratio. dietary increased apparent total tract digestibility crude protein (CP) gross energy (GE, P < 0.05) d 14 compared other two GE (P 28 control group. Compared group, pigs fed IgM concentration, decreased IL-6 content MDA, IL-1β, serum. Dietary supplementation T-AOC 0.05), GSH-Px, MDA liver jejunum Pig activity duodenal lipase 0.05).At both concentrations, addition abundance Firmicutes intestinal flora > Proteobacteria. 2, diets 1:1 got higher nutrients than 0.05). Supplementation serum ALT, DAO contents BUN, IL1-β IL-1β T4 CAT, GSH-Px significantly levels SOD T1 T3 groups. Overall, MSCFA had positive effect piglets, improving performance enhancing antioxidant capacity capacity, alleviating inflammatory response, flora. Adding can achieve best which is

Language: Английский

Citations

0