Nanomaterial-integrated injectable hydrogels for craniofacial bone reconstruction DOI Creative Commons
Yong Xia, Zihan Chen,

Zebin Zheng

et al.

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: Aug. 31, 2024

The complex anatomy and biology of craniofacial bones pose difficulties in their effective precise reconstruction. Injectable hydrogels (IHs) with water-swollen networks are emerging as a shape-adaptive alternative for noninvasively rebuilding bones. advent versatile nanomaterials (NMs) customizes IHs strengthened mechanical properties therapeutically favorable performance, presenting excellent contenders over traditional substitutes. Structurally, NM-reinforced energy dissipative covalently crosslinked, providing the mechanics necessary to support structures physiological functions. Biofunctionally, incorporating unique NMs into IH expands plethora biological activities, including immunomodulatory, osteogenic, angiogenic, antibacterial effects, further favoring controllable dynamic tissue regeneration. Mechanistically, NM-engineered optimize physical traits direct cell responses, regulate intracellular signaling pathways, control release biomolecules, collectively bestowing structure-induced features multifunctionality. By encompassing state-of-the-art advances NM-integrated IHs, this review offers foundation future clinical translation bone

Language: Английский

An injectable gelatin methacrylate containing surface-imprinted chitosan-modified bioglass microspheres for potential periodontitis treatment DOI

Reihaneh Khademi,

Masoumeh Alsadat Hosseini,

Mahshid Kharaziha

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 302, P. 140561 - 140561

Published: Jan. 31, 2025

Language: Английский

Citations

0
Recent advances in tailored chitosan-based hydrogels for bone regeneration and repair DOI
Peipei Feng,

Chaonan He,

Guanrong Li

et al.

Materials Chemistry Frontiers, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

This paper summarizes the preparation processes of tailored chitosan-based hydrogels, along with their specific applications in bone regeneration, aiming to inspire innovative designs for hydrogels and foster expanded applications.

Language: Английский

Citations

0
Nanominerals: a multifaceted biomaterial for regenerative medicine and drug delivery DOI
Aishik Chakraborty, Wei Luo, Amauri J. Paula

et al.

Expert Opinion on Drug Delivery, Journal Year: 2025, Volume and Issue: unknown

Published: April 11, 2025

Language: Английский

Citations

0
Nanomaterial-integrated injectable hydrogels for craniofacial bone reconstruction DOI Creative Commons
Yong Xia, Zihan Chen,

Zebin Zheng

et al.

Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: Aug. 31, 2024

The complex anatomy and biology of craniofacial bones pose difficulties in their effective precise reconstruction. Injectable hydrogels (IHs) with water-swollen networks are emerging as a shape-adaptive alternative for noninvasively rebuilding bones. advent versatile nanomaterials (NMs) customizes IHs strengthened mechanical properties therapeutically favorable performance, presenting excellent contenders over traditional substitutes. Structurally, NM-reinforced energy dissipative covalently crosslinked, providing the mechanics necessary to support structures physiological functions. Biofunctionally, incorporating unique NMs into IH expands plethora biological activities, including immunomodulatory, osteogenic, angiogenic, antibacterial effects, further favoring controllable dynamic tissue regeneration. Mechanistically, NM-engineered optimize physical traits direct cell responses, regulate intracellular signaling pathways, control release biomolecules, collectively bestowing structure-induced features multifunctionality. By encompassing state-of-the-art advances NM-integrated IHs, this review offers foundation future clinical translation bone

Language: Английский

Citations

1