Royal Society of Chemistry eBooks,
Journal Year:
2024,
Volume and Issue:
unknown, P. 162 - 202
Published: Oct. 4, 2024
Over
the
last
decade,
a
range
of
studies
have
demonstrated
that
various
fitness-related
behaviours
are
vulnerable
to
disruption
induced
by
contaminants
emerging
concern
(CECs)
and
legacy
pollutants.
However,
behavioural
responses
animals
when
exposed
pollutants/contaminants
rarely
included
in
discussions
about
regulation
chemicals.
Thus,
improve
our
understanding
opportunities
challenges
for
ecotoxicology,
this
chapter
presents
synthesis
endpoints
experimental
procedures
used
evaluate
response
Nile
tilapia
(Oreochromis
niloticus
–
non-conventional
species
ecotoxicology)
different
CECs
By
focusing
on
methodological
possibilities
be
evaluating
behaviour
Neotropical
species,
we
shed
light
feasibility
reasonableness
using
animal
model
as
complement
or
alternative
use
traditionally
toxicology.
Environmental Pollution,
Journal Year:
2023,
Volume and Issue:
338, P. 122694 - 122694
Published: Oct. 4, 2023
Lambda-cyhalothrin,
also
known
as
cyhalothrin,
is
an
efficient,
broad-spectrum,
quick-acting
pyrethroid
insecticide
and
acaricide
the
most
powerful
in
world.
However,
there
increasing
evidence
that
lambda-cyhalothrin
closely
related
to
a
variety
of
toxicity
drawbacks
(hepatotoxicity,
nephrotoxicity,
neurotoxicity
reproductive
toxicity,
among
others)
non-target
organisms,
oxidative
stress
seems
be
main
mechanism
toxicity.
This
manuscript
reviews
mitochondrial
damage
induced
by
signalling
pathways
involved
this
process,
indicating
occupies
important
position
The
antioxidants
alleviate
discussed.
In
addition,
metabolites
major
metabolic
enzymes
reactions
are
summarized.
review
article
reveals
key
toxicity-oxidative
suggests
use
effective
method
for
preventing
Fishes,
Journal Year:
2023,
Volume and Issue:
8(4), P. 199 - 199
Published: April 12, 2023
A
new
insight
into
the
synthesis
of
herbal
plant
(White
poplar,
Poplus
alba)
leave
extract
using
chitosan
nanocapsule
was
studied.
The
in
vitro
antibacterial
activity
white
poplar
(CWPNC)
against
Streptococcus
agalactiae
(S.
agalactiae)
determined.
About
120
fish
were
categorized
for
7
days
four
groups.
first
and
second
groups
treated
with
0
mg/L
3
CWPNC
water,
respectively,
without
being
challenged;
group
a
control.
third
fourth
(CWPNC
+
S.
CWPNC,
challenged
(0.5
×
107
CFU/mL).
obtained
results
revealed
that
had
an
agalactiae.
Moreover,
infection
caused
significant
elevation
(p
<
0.05)
lipid
peroxidation
(malondialdehyde)
hepatorenal
biomarkers,
as
well
lowest
survival
rate
(33.33%).
depletion
level
antioxidants
(catalase
superoxide
dismutase)
immune
indicators
(immunoglobulin,
lysozyme
activity,
complement
3)
consequences
infection.
Treatment
infected
alleviated
these
bad
circumstances.
Frontiers in Pharmacology,
Journal Year:
2024,
Volume and Issue:
15
Published: May 1, 2024
Introduction:
The
synthetic
pyrethroid
derivative
fenpropathrin
(FNE),
a
commonly
used
insecticide,
has
been
associated
with
various
toxic
effects
in
mammals,
particularly
neurotoxicity.
study
addressed
the
hallmarks
of
pathophysiology
Parkinson’s
disease
upon
oral
exposure
to
mainly
alteration
dopaminergic
markers,
oxidative
stress,
and
molecular
docking
rat
models.
In
addition,
protective
effect
curcumin-encapsulated
chitosan
nanoparticles
(CRM-Chs-NPs)
was
also
assessed.
Methods:
60-day
trial,
40
male
Sprague
Dawley
rats
were
divided
into
4
groups:
Control,
CRM-Chs-NPs
(curcumin-encapsulated
nanoparticles),
FNE
(15
mg/kg
bw),
+
CRM-Chs-NPs.
Results:
induced
reactive
oxygen
species
generation,
ATP
production
disruption,
activation
inflammatory
apoptotic
pathways,
mitochondrial
function
dynamics
impairment,
neurotransmitter
level
perturbation,
mitophagy
promotion
brains.
Molecular
analysis
revealed
that
interacts
key
binding
sites
dopamine
synthesis
transport
proteins.
On
other
hand,
mitigated
FNE’s
by
enhancing
dynamics,
antioxidant
activity,
promoting
anti-inflammatory
antiapoptotic
responses.
Conclusion:
summary,
appears
induce
degeneration
through
mechanisms,
emerged
as
potential
therapeutic
intervention
for
protecting
nervous
tissue
microenvironment.
