Organelle synergy unleashed: Modulating mitochondrial-endoplasmic reticulum contacts with a self-assembled prodrug amplifies ferroptosis for innovative cancer therapy DOI

Junyan Zhuang,

Renming Fan,

Weike Liao

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 495, P. 153364 - 153364

Published: June 20, 2024

Language: Английский

Resveratrol Inhibits VDAC1-Mediated Mitochondrial Dysfunction to Mitigate Pathological Progression in Parkinson’s Disease Model DOI
Shenglan Feng, Jianjun Gui, Bingqing Qin

et al.

Molecular Neurobiology, Journal Year: 2024, Volume and Issue: unknown

Published: May 31, 2024

Language: Английский

Citations

5
Autophagy in Crohn’s Disease: Converging on Dysfunctional Innate Immunity DOI Creative Commons
Kibrom M. Alula, Arianne L. Theiss

Cells, Journal Year: 2023, Volume and Issue: 12(13), P. 1779 - 1779

Published: July 4, 2023

Crohn’s disease (CD) is a chronic inflammatory bowel marked by relapsing, transmural intestinal inflammation driven innate and adaptive immune responses. Autophagy multi-step process that plays critical role in maintaining cellular homeostasis degrading intracellular components, such as damaged organelles invading bacteria. Dysregulation of autophagy CD revealed the identification several susceptibility genes, including ATG16L1, IRGM, NOD2, LRRK2, ULK1, ATG4, TCF4, are involved autophagy. In this review, altered mucosal response context discussed, with specific focus on dendritic cells, macrophages, Paneth goblet cells. Selective autophagy, xenophagy, ERphagy, mitophagy, play crucial roles these discussed. As our understanding pathogenesis evolves, development autophagy-targeted therapeutics may benefit subsets patients harboring impaired

Language: Английский

Citations

13
The emerging significance of mitochondrial targeted strategies in NAFLD treatment DOI
Tao Zhang,

Yingli Nie,

Jiliang Wang

et al.

Life Sciences, Journal Year: 2023, Volume and Issue: 329, P. 121943 - 121943

Published: July 15, 2023

Language: Английский

Citations

13
The role of endoplasmic reticulum stress, mitochondrial dysfunction and their crosstalk in intervertebral disc degeneration DOI
Dengbo Yao, Enming Chen, Yuxi Li

et al.

Cellular Signalling, Journal Year: 2023, Volume and Issue: 114, P. 110986 - 110986

Published: Nov. 23, 2023

Language: Английский

Citations

12
Organelle synergy unleashed: Modulating mitochondrial-endoplasmic reticulum contacts with a self-assembled prodrug amplifies ferroptosis for innovative cancer therapy DOI

Junyan Zhuang,

Renming Fan,

Weike Liao

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 495, P. 153364 - 153364

Published: June 20, 2024

Language: Английский

Citations

4