Tough, self-healing, adhesive double network conductive hydrogel based on gelatin-polyacrylamide covalently bridged by oxidized sodium alginate for durable wearable sensors

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 276, P. 133802 - 133802

Published: July 10, 2024

Language: Английский

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Multifunctional polypeptide-based hydrogel bio-adhesives with pro-healing activities and their working principles

Advances in Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 327, P. 103155 - 103155

Published: April 16, 2024

Language: Английский

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Research progress of natural polysaccharide-based and natural protein-based hydrogels for bacteria-infected wound healing

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 496, P. 153803 - 153803

Published: July 6, 2024

Language: Английский

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Development of a Multifunctional Composite Hydrogel for Enhanced Wound Healing: Hemostasis, Sterilization, and Long-Term Moisturizing Properties

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(2), P. 2972 - 2983

Published: Jan. 3, 2024

Meeting the diverse requirements of effective wound repair while surpassing single-function limitations traditional dressings is a significant challenge. In this study, we successfully synthesized an inclusion complex 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) and iodine using saturated aqueous solution method. Additionally, dialdehyde cellulose (DAC) was extracted from fat-free cotton through oxidation. To enhance healing, l-glutamine (l-glu) utilized as functional molecule, resulting in composite hydrogels with hemostatic, sterilizing, wound-healing-promoting properties that were achieved by adsorbing complex. Through TG SEM analysis, confirmed effectively accommodated cyclodextrin uniformly attached to hydrogel. The hydrogel exhibits exceptional long-term moisturizing bactericidal properties, also demonstrating excellent swelling, oxygen permeability, hemolytic, mechanical fully satisfying treatment. External coagulation tests revealed can rapidly coagulate 4.5 times its own weight blood. Moreover, full-thickness scald mouse model, promotes healing. development multifunctional presents novel approach advance dressing research, holding substantial potential for practical applications.

Language: Английский

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Hydroxypropyl chitosan/ε-poly-l-lysine based injectable and self-healing hydrogels with antimicrobial and hemostatic activity for wound repair

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 337, P. 122135 - 122135

Published: April 7, 2024

Language: Английский

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Natural Polymer‐Based Materials for Wound Healing Applications

Advanced NanoBiomed Research, Journal Year: 2024, Volume and Issue: 4(5)

Published: Feb. 22, 2024

Skin injuries pose significant health challenges, with conditions like burns and diabetic, venous, pressure ulcers presenting complex wound management scenarios. Effective care strategies for these encompass a range of interventions, from simple dressings to bioactive materials surgical procedures involving skin substitutes grafting. This review explores the potential natural polymers, including silk, collagen, gelatin, elastin, cellulose, chitosan, alginate, hyaluronic acid, in management. Natural polymers offer several advantages, abundance, biodegradability, compatibility traditional modern material fabrication techniques, have demonstrated safety efficacy clinical applications, modulating various facets healing process. Highlighting preclinical studies, along commercial products, this showcases versatility utility provides insights into emerging developments, such as 3D bioprinting stimuli‐responsive materials, which hold promise personalized treatments. Additionally, we discuss importance format morphology engineering next generation substitutes, offering pathway optimize enhanced outcomes.

Language: Английский

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Dandelion-derived vesicles-laden hydrogel dressings capable of neutralizing Staphylococcus aureus exotoxins for the care of invasive wounds

Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 368, P. 355 - 371

Published: March 6, 2024

Language: Английский

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Conducting polymer hydrogels based on supramolecular strategies for wearable sensors

Exploration, Journal Year: 2024, Volume and Issue: 4(5)

Published: March 14, 2024

Abstract Conductive polymer hydrogels (CPHs) are gaining considerable attention in developing wearable electronics due to their unique combination of high conductivity and softness. However, the absence interactions, incompatibility between hydrophobic conductive polymers (CPs) hydrophilic networks gives rise inadequate bonding CPs hydrogel matrices, thereby significantly impairing mechanical electrical properties CPHs constraining utility electronic sensors. Therefore, endow with good performance, it is necessary ensure a stable robust network CPs. Encouragingly, recent research has demonstrated that incorporating supramolecular interactions into enhances interaction, improving overall CPH performance. comprehensive review focusing on (SCPH) for sensing applications currently lacking. This provides summary typical strategies employed development high‐performance elucidates SCPHs closely associated Moreover, discusses fabrication methods classification SCPH sensors, while also exploring latest application scenarios Finally, challenges sensors offers suggestions future advancements.

Language: Английский

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Hydrogels: Classifications, fundamental properties, applications, and scopes in recent advances in tissue engineering and regenerative medicine – A comprehensive review

Arabian Journal of Chemistry, Journal Year: 2024, Volume and Issue: 17(10), P. 105968 - 105968

Published: Aug. 17, 2024

Hydrogels are three-dimensional structures that serve as substitutes for the extracellular matrix (ECM) and possess outstanding physicochemical biochemical characteristics. They gaining importance in regenerative medicine because of their similarity to natural terms moisture content wound tissue healing permeability. Tissue engineering advancements have resulted development flexible hydrogels mimic dynamic characteristics ECM. Several approaches been applied produce from biopolymers with enhanced functional structural different applications (TERM). This review provides a comprehensive overview hydrogel healing, engineering, drug delivery systems. We outline types based on physical chemical crosslinking, fundamental properties, TERM. article provided recent literature within five years. Recent developments biopolymer-based state-of-the-art discussed, emphasizing significant challenges future perspectives.

Language: Английский

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Near-infrared light-activatable, analgesic nanocomposite delivery system for comprehensive therapy of diabetic wounds in rats

Biomaterials, Journal Year: 2024, Volume and Issue: 305, P. 122467 - 122467

Published: Jan. 7, 2024

Language: Английский

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