Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
34(31)
Published: Dec. 6, 2023
Abstract
The
utilization
of
gallium
(Ga)‐based
liquid
metals
(LMs)
as
functional
materials
in
bioelectronics
has
been
extensively
explored
over
the
past
decade
a
key
to
stimulation
biological
systems
and
recording
signals.
motivation
behind
this
class
electronics
is
driven
by
opportunities
exploit
mechanical
properties
similar
tissues.
These
bioelectronic
devices
are
required
maintain
functionality
under
deformation
and,
especially
for
implantable
applications,
should
interface
with
tissues
minimally
invasive
manner.
LMs
attractive
such
applications
due
their
ability
deform
while
retaining
electrical
conductivity.
Furthermore,
unlike
most
liquids
that
form
droplets
minimize
surface
energy,
ultrathin
solid‐state
oxide
layer
on
outer
enables
them
be
shaped
specific
3D
patterns.
Unlike
mercury,
Ga‐based
considered
biocompatible
low
toxicity
vapor
pressure,
highlighting
potential
advantageous
bioelectronics.
This
review
comprehensively
presents
fundamental
aspects
these
materials,
focus
effectiveness
stimulating
tissues,
well
diverse
soft
stretchable
electrodes
Additionally,
investigates
additional
strategies
aimed
at
driving
future
advancements
field.
Advanced Healthcare Materials,
Journal Year:
2022,
Volume and Issue:
12(3)
Published: Oct. 31, 2022
Abstract
Recently,
room‐temperature
liquid
metals
have
attracted
increasing
attention
from
researchers
owing
to
their
excellent
material
properties.
Systematic
interpretation
of
the
potential
toxicity
issues
involved
is
essential
for
a
wide
range
applications,
especially
in
biomedical
and
healthcare
fields.
However,
even
with
exponential
growth
related
studies,
investigation
toxicological
impact
possible
hazards
organisms
still
its
infancy.
This
review
aims
provide
comprehensive
summary
current
frontier
knowledge
on
metal
toxicology
biocompatibility
different
environments.
Based
recent
this
focuses
Ga
Bi‐based
states.
It
necessary
evaluate
considering
rapid
increase
research
utilization
such
composites.
Finally,
existing
challenges
are
discussed
suggestions
provided
further
clarify
mechanisms
strategies
avoid
adverse
effects.
In
addition
resolving
doubts
public
concern
about
metals,
expected
promote
healthy
sustainable
development
metal‐based
materials
use
diverse
areas,
those
health
care.
Journal of the American Chemical Society,
Journal Year:
2022,
Volume and Issue:
144(15), P. 6779 - 6790
Published: March 16, 2022
This
report
presents
nanoparticles
composed
of
a
liquid
gallium
core
with
reduced
graphene
oxide
(RGO)
shell
(Ga@RGO)
tunable
thickness.
The
particles
are
produced
by
simple,
one-pot
nanoprobe
sonication
method.
high
near-infrared
absorption
RGO
results
in
photothermal
energy
conversion
light
to
heat
42.4%.
efficient
conversion,
combined
the
large
intrinsic
thermal
expansion
coefficient
gallium,
allows
be
used
for
photoacoustic
imaging,
that
is,
into
vibrations
useful
imaging.
Ga@RGO
fivefold
and
twofold
enhancement
signals
compared
bare
gold
nanorods
(a
commonly
contrast
agent),
respectively.
A
theoretical
model
further
reveals
factors
affect
performance
Ga@RGO.
These
core–shell
not
only
can
serve
as
imaging
agents
but
also
pave
new
way
rationally
design
metal-based
nanomaterials
specific
multi-functionality
biomedical
applications.
Advanced Functional Materials,
Journal Year:
2022,
Volume and Issue:
32(41)
Published: Aug. 21, 2022
Abstract
Solar‐driven
evaporation
is
a
promising
strategy
to
relieve
fresh
water
stress
in
the
world.
For
an
evaporator,
it
necessary
be
equiped
with
novel
photothermal
conversion
materials
and
regulate
heat
energy
loss
solar‐driven
generation
process
for
efficiency.
Herein,
eutectic
gallium‐indium
(EGaIn)/polyaniline
(PANI)
complex
(EP)
cellulose
nanocrystals
(CNCs)
are
explored
as
light
absorber
broadband
absorbing
dispersant
particles
uniformity.
Based
on
Bénard–Marangoni
effect,
dual‐network
poly(vinyl
alcohol)/poly(acrylamide)
(PM)
hydrogel
evaporator
water/ethylene
glycol
solvent
transfer.
Specifically,
CNCs
EP
incorporated,
endowed
excellent
mechanical
properties,
performance,
electrical
characteristics.
Surface
temperature
of
can
reach
≈38.7
°C
under
1
sun
illumination
h.
combination
absorption
its
rate
higher
than
1.50
kg
m
–2
h
–1
.
The
engineered
synergy
also
gives
hydrogels
multiple
sensory
capabilities,
skin‐like
function,
power
generation.
This
work
demonstrates
EGaIn‐based
new
approach
transfer
highly
evaporation,
focus
integration
multifunctional
solar
systems.
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(2), P. 435 - 435
Published: Feb. 17, 2022
Cancer
continues
to
represent
a
global
health
concern,
imposing
an
ongoing
need
research
for
better
treatment
alternatives.
In
this
context,
nanomedicine
seems
be
the
solution
existing
problems,
bringing
unprecedented
results
in
various
biomedical
applications,
including
cancer
therapy,
diagnosing,
and
imaging.
As
numerous
studies
have
uncovered
advantageous
properties
of
nanoscale
metals,
review
aims
present
metal-based
nanoparticles
that
are
most
frequently
employed
applications.
This
paper
follows
description
relevant
made
metal
derivatives,
hybrids,
alloys,
further
discussing
more
detail
their
potential
applications
management,
ranging
from
delivery
chemotherapeutics,
vaccines,
genes
ablative
hyperthermia
therapies
theranostic
platforms.
Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology,
Journal Year:
2022,
Volume and Issue:
14(4)
Published: April 13, 2022
Abstract
Copper‐based
nanomaterials
(Cu‐based
NMs)
with
favorable
biocompatibility
and
unique
properties
have
attracted
the
attention
of
many
biomedical
researchers.
Cu‐based
NMs
are
one
most
widely
studied
materials
in
cancer
treatment.
In
recent
years,
great
progress
has
been
made
field
biomedicine,
especially
treatment
diagnosis
tumors.
This
review
begins
classification
synthetic
strategies
NMs.
Then,
according
to
abundant
special
NMs,
their
application
biomedicine
is
summarized
detail.
For
imaging,
such
as
photoacoustic
positron
emission
tomography
multimodal
imaging
based
on
summarized,
well
improve
diagnostic
effectiveness.
Moreover,
a
series
structures
functions
underlying
property
activity
relationship
were
shown
highlight
promising
therapeutic
performance.
used
monotherapies,
photothermal
therapy
(PTT)
chemodynamic
(CDT).
sophisticated
design
composition,
structure,
surface
fabrication
can
endow
these
more
modalities
therapy.
To
further
efficiency
treatment,
combined
was
introduced
Finally,
challenges,
critical
factors,
future
prospects
for
clinical
translation
multifunctional
theranostic
agents
also
considered
discussed.
The
aim
this
provide
better
understanding
key
consideration
rational
increasingly
important
new
paradigm
agents.
article
categorized
under:
Therapeutic
Approaches
Drug
Discovery
>
Nanomedicine
Oncologic
Disease
Diagnostic
Tools
Vivo
Nanodiagnostics
Imaging
Bioactive Materials,
Journal Year:
2023,
Volume and Issue:
31, P. 53 - 62
Published: Aug. 8, 2023
Certain
types
of
cationic
metal
ions,
such
as
Mn2+
are
able
to
activate
immune
functions
via
the
stimulator
interferon
genes
(STING)
pathway,
showing
potential
applications
in
eliciting
antitumor
immunity.
How
anionic
ions
interact
with
cells
remains
largely
unknown.
Herein,
selecting
from
a
range
and
we
were
excited
discover
that
MoO42−
could
act
cGAS-STING
agonist
further
confirmed
capability
pathway.
Inspired
by
findings,
synthesized
manganese
molybdate
nanoparticles
polyethylene
glycol
modification
(MMP
NDs)
for
cancer
metalloimmunotherapy.
Meanwhile,
MMP
NDs
consume
glutathione
(GSH)
over-expressed
tumors
induce
ferroptosis
owing
high-valence
Mo
Mn
elicit
tumor-specific
responses,
which
was
amplified
MMP-triggered
activation.
In
turn,
activated
CD8+
T
secrete
high
levels
γ
(IFN-γ)
reduced
GPX4
expression
tumor
trigger
ferroptosis-specific
lipid
peroxidation,
constituted
"cycle"
therapy.
As
result,
metalloimmunotherapy
systemic
administration
offered
remarkable
inhibition
effect
variety
models.
Our
work
first
time
discovered
ability
system
rationally
designed
bimetallic
oxide
nanostructures
multifunctional
therapeutic
nanoplatform
immunotherapy.
