Nanodelivery Systems as a Novel Strategy to Overcome Treatment Failure of Cancer DOI

He Shi,

Xinyu Gou,

Shuheng Zhang

et al.

Small Methods, Journal Year: 2023, Volume and Issue: 8(1)

Published: Oct. 17, 2023

Abstract Despite the tremendous progress in cancer treatment recent decades, cancers often become resistant due to multiple mechanisms, such as intrinsic or acquired multidrug resistance, which leads unsatisfactory effects accompanying metastasis and recurrence, ultimately failure. With a deeper understanding of molecular mechanisms tumors, researchers have realized that designs targeting tumor resistance would be promising strategy break therapeutic deadlock. Nanodelivery systems excellent physicochemical properties, including highly efficient tissue‐specific delivery, substantial specific surface area, controllable chemistry, endow nanodelivery with capabilities precise targeting, deep penetration, responsive drug release, codelivery, multimodal synergy, are currently widely used biomedical researches bring new dawn for overcoming resistance. Based on this review summarizes research improve efficacy years offers prospects challenges application

Language: Английский

Architecturally designed sequential-release hydrogels DOI
Dan Zhang, Zimu Li, Li Yang

et al.

Biomaterials, Journal Year: 2023, Volume and Issue: 303, P. 122388 - 122388

Published: Nov. 9, 2023

Language: Английский

Citations

11
A carrier-free metal-phenolic network with enhanced ferroptosis-immunotherapy for overcoming tumor resistance and metastasis DOI
Ning Zhang, Zijia Wang, Gen Li

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 488, P. 150780 - 150780

Published: March 27, 2024

Language: Английский

Citations

4
Tumor Microenvironment-Responsive Biodegradable Nanomedicine for Self-Enhanced Synergistic Chemo-, Photothermal, and Chemodynamic Therapy DOI
Hanxiao Tang,

Zhi-Hang He,

Chenguang Liu

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 20, 2024

The nanoscale multidrug codelivery system for synergistic therapy is an effective strategy tumor treatment. However, the low drug delivery efficiency and poor therapeutic effects limit its application. Here, based on coordination effect of Artemisinin (Art), quercetin (Qc), Fe

Language: Английский

Citations

4
Novel insights and future perspectives on the nanomedicine-mediated synergistic anticancer effect of the combination of ferroptosis and photothermal therapy DOI
Haisong Qi, Haiying Wang, Lu Wang

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 156921 - 156921

Published: Oct. 1, 2024

Language: Английский

Citations

4
Nanodelivery Systems as a Novel Strategy to Overcome Treatment Failure of Cancer DOI

He Shi,

Xinyu Gou,

Shuheng Zhang

et al.

Small Methods, Journal Year: 2023, Volume and Issue: 8(1)

Published: Oct. 17, 2023

Abstract Despite the tremendous progress in cancer treatment recent decades, cancers often become resistant due to multiple mechanisms, such as intrinsic or acquired multidrug resistance, which leads unsatisfactory effects accompanying metastasis and recurrence, ultimately failure. With a deeper understanding of molecular mechanisms tumors, researchers have realized that designs targeting tumor resistance would be promising strategy break therapeutic deadlock. Nanodelivery systems excellent physicochemical properties, including highly efficient tissue‐specific delivery, substantial specific surface area, controllable chemistry, endow nanodelivery with capabilities precise targeting, deep penetration, responsive drug release, codelivery, multimodal synergy, are currently widely used biomedical researches bring new dawn for overcoming resistance. Based on this review summarizes research improve efficacy years offers prospects challenges application

Language: Английский

Citations

10