RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(53), P. 39163 - 39172
Published: Jan. 1, 2024
The
flexible
design
and
unique
physical
chemical
properties
of
self-assembled
peptides
have
shown
great
potential
for
applications
in
the
fields
materials
science,
life
environmental
science.
Peptide
nanofibers
(PNFs),
as
a
kind
bioactive
nanomaterials,
possess
excellent
biocompatibility,
designability,
multifaceted
functionalizability.
In
this
work,
we
describe
PNFs
that
by
peptide
molecules
carriers
bimetallic
nanosheets
(BMNS),
leading
to
development
hybrid
BMNS-PNFs,
with
properties.
BMNS-PNFs
exhibit
photothermal
conversion
efficiency
(PCE)
up
31.57%,
can
be
used
nanoplatform
therapy
(PTT)
lung
tumour
cells.
Through
results,
it
is
reduce
cytotoxicity
cancer
cell
killing
effects,
rates
more
than
95%
90%
cells
HCC2279
PC9,
respectively.
Finally,
comprehensive
PTT
performance
analysed
Ranking
Efficiency
Performance
(REP),
REP
value
calculated
0.741.
sequences
assemble
into
study
are
instructive
functional
structural
modulation
molecular
self-assembly,
constructed
bimetallic-biomolecular
provide
strategy
medical
bioengineering.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(36)
Published: March 29, 2024
Abstract
Fluorescence
imaging
in
the
second
near‐infrared
window
(NIR‐II,
1000–1700
nm)
has
aroused
immense
attention
for
biomedical
applications,
offering
exceptional
advantages
such
as
ultra‐low
photon
scattering
and
increased
tissue
penetration.
Among
NIR‐II‐emitted
organic
dyes,
Boron
dipyrromethene
(BODIPY),
emerged
a
noteworthy
candidate.
BODIPY,
distinguished
by
its
controllable
molecular
structure
optical
properties,
outstanding
fluorescence
quantum
yields,
high
molar
absorption
coefficients,
remarkable
chemical
stability,
undergone
comprehensive
investigation
extensive
exploration
within
realm
of
biological
theranostics.
This
work
aims
to
provide
summary
advancements
development
design
strategies
NIR‐II
BODIPY
fluorophores
tailored
advanced
phototheranostics.
Initially,
elucidates
several
representative
strategies,
concluding
electron‐programming
strategy,
extension
conjugated
backbone,
J‐aggregation
strategic
establishment
activatable
fluorophores,
which
enhance
skeletons.
Subsequently,
developments
fluorescent
BODIPY‐based
nanoplatforms
applications
are
intricately
elaborated.
In
conclusion,
this
outlines
future
efforts
directions
refining
meet
evolving
clinical
demands.
It
is
anticipated
that
contribution
may
feasible
reference
thereby
advancing
their
potential
practices.
ACS Applied Bio Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 1, 2024
Recent
advances
have
been
made
in
second
near-infrared
(NIR-II)
fluorescence
bioimaging
and
many
related
applications
because
of
its
advantages
deep
penetration,
high
resolution,
minimal
invasiveness,
good
dynamic
visualization.
To
achieve
high-performance
NIR-II
bioimaging,
various
materials
probes
with
bright
emission
extensively
explored
the
past
few
years.
Among
these
emissive
materials,
conjugated
polymers
small
molecules
attracted
wide
interest
due
to
their
native
biosafety
tunable
optical
performance.
This
review
summarizes
brightness
strategies
available
for
highlights
recent
developments
bioimaging.
A
concise,
detailed
overview
molecular
design
regulatory
approaches
is
provided
terms
brightness,
long
wavelengths,
superior
imaging
Then,
typical
cases
which
are
used
as
introduced
by
providing
step-by-step
examples.
Finally,
current
problems
challenges
associated
accessing
briefly
discussed,
significance
future
prospects
proposed
offer
helpful
guidance
development
materials.
Small Methods,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 9, 2025
Recent
advances
in
the
development
of
tumor-targeting
nanoparticles
(NPs)
significantly
enhance
cancer
therapies
by
effectively
increasing
therapeutic
window
drugs,
improving
response
tumor
cells,
and
augmenting
anti-tumor
immunity.
However,
understanding
process
remains
elusive
because
complex
vivo
behavior
nanoparticles.
Various
factors
are
reported
to
alter
this
process;
however,
systematic
studies
on
mechanisms
remain
limited.
In
review,
an
overview
current
strategies
for
targeting
their
applications
chemotherapy
immunotherapy,
with
a
focus
advancement
various
barriers
effective
penetration
is
provided.
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: April 10, 2024
Photothermal
immunotherapy
is
regarded
as
the
ideal
cancer
therapeutic
modality
to
against
malignant
solid
tumors;
however,
its
benefits
are
often
modest
and
require
improvement.
In
this
study,
a
thermoresponsive
nanoparticle
(BTN@LND)
composed
of
photothermal
agent
(PTA)
pyroptosis
inducer
(lonidamine)
were
developed
enhance
applications.
Specifically,
our
"two-step"
donor
engineering
strategy
produced
strong
NIR-II-absorbing
organic
small-molecule
PTA
(BTN)
that
exhibited
high
NIR-II
performance
(ε
Nanomaterials,
Journal Year:
2024,
Volume and Issue:
14(9), P. 797 - 797
Published: May 3, 2024
Nanomaterials,
with
unique
physical,
chemical,
and
biocompatible
properties,
have
attracted
significant
attention
as
an
emerging
active
platform
in
cancer
diagnosis
treatment.
Amongst
them,
metal–organic
framework
(MOF)
nanostructures
are
particularly
promising
a
nanomedicine
due
to
their
exceptional
surface
functionalities,
adsorption
organo-inorganic
hybrid
characteristics.
Furthermore,
when
bioactive
substances
integrated
into
the
structure
of
MOFs,
these
materials
can
be
used
anti-tumor
agents
superior
performance
compared
traditional
nanomaterials.
In
this
review,
we
highlight
most
recent
advances
MOFs-based
for
tumor
therapy,
including
application
treatment
underlying
mechanisms.
