Weight Loss Supplements DOI Creative Commons
Irene Dini, Andrea Mancusi

Molecules, Journal Year: 2023, Volume and Issue: 28(14), P. 5357 - 5357

Published: July 12, 2023

Being overweight or obese can predispose people to chronic diseases and metabolic disorders such as cardiovascular illnesses, diabetes, Alzheimer’s disease, cancer, which are costly public health problems leading causes of mortality worldwide. Many hope solve this problem by using food supplements, they be self-prescribed, contain molecules natural origin considered incapable causing damage health, the only sacrifice require is economic. The market offers supplements containing plant-derived (e.g., primary secondary metabolites, vitamins, fibers), microbes (probiotics), microbial-derived fractions (postbiotics). They control lipid carbohydrate metabolism, reduce appetite (interacting with central nervous system) adipogenesis, influence intestinal microbiota activity, increase energy expenditure. Unfortunately, copious choice products different legislation on worldwide confuse consumers. This review summarizes activity toxicity dietary for weight clarify their potentiality adverse reactions. A lack research regarding commercially available has been noted. Supplements postbiotic moieties particular interest. easier store transport safe even a deficient immune system.

Language: Английский

Comparative evaluation of pseudocereal peptides: A review of their nutritional contribution DOI
Muhammad Usman, Prasanna J. Patil, Arshad Mehmood

et al.

Trends in Food Science & Technology, Journal Year: 2022, Volume and Issue: 122, P. 287 - 313

Published: Feb. 20, 2022

Language: Английский

Citations

30

Sciadonic acid attenuates high-fat diet-induced obesity in mice with alterations in the gut microbiota DOI
Lin Chen,

Qihong Jiang,

Chenkai Jiang

et al.

Food & Function, Journal Year: 2023, Volume and Issue: 14(6), P. 2870 - 2880

Published: Jan. 1, 2023

Sciadonic acid (SA) could alleviate obesity and its related metabolic disorders. SA altered the gut microbial structure composition in obese mice. ameliorated lipid metabolism disorders by activating PPARα/SREBP-1C/FAS pathway.

Language: Английский

Citations

21

Nuts, Energy Balance and Body Weight DOI Open Access
David J. Baer, Michelle Dalton, John E. Blundell

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(5), P. 1162 - 1162

Published: Feb. 25, 2023

Over several decades, the health benefits of consuming nuts have been investigated, resulting in a large body evidence that can reduce risk chronic diseases. The consumption nuts, being higher-fat plant food, is restricted by some order to minimize weight gain. In this review, we discuss factors related energy intake from including food matrix and its impact on digestibility, role regulating appetite. We review data randomized controlled trials observational studies conducted examine relationship between nut or mass index. Consistently, RCTs cohorts indicates higher does not cause greater gain; rather, may be beneficial for control prevention long-term Multiple mechanisms likely contribute these findings, aspects composition which affect nutrient availability as well satiety signaling.

Language: Английский

Citations

17

Dietary trends and obesity in Saudi Arabia DOI Creative Commons
Noara Alhusseini,

Nawra Alsinan,

Shahad Almutahhar

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 11

Published: Jan. 11, 2024

Dietary habits in Saudi Arabia have been shifting toward the Western diet, which is high fat, salt, and sugar, leading to a obesity rate. Different dietary strategies such as Ketogenic Diet (KD), Intermittent Fasting (IF), Gluten Free (GFD), Calorie Restriction (CRD) shown an influential role weight loss. This study aimed compare trending diets correlate different types of diet with lifestyle among adults Arabia.

Language: Английский

Citations

8

Antidiabetic potentials of crude and purified sulphated polysaccharides isolated from Gracilaria gracilis, a seaweed from South Africa DOI Creative Commons

Leah R. Pillay,

Tosin A. Olasehinde, Kolawole A. Olofinsan

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(15), P. e35729 - e35729

Published: Aug. 1, 2024

Over 90 % of all cases diabetes that have been diagnosed are type 2 (T2D), a disease exacerbated by an increase in sedentary behaviour, bad eating habits, and obesity. This study investigated the antidiabetic properties

Language: Английский

Citations

7

Adipocentric origin of the common cardiometabolic complications of obesity in the young up to the very old: pathophysiology and new therapeutic opportunities DOI Creative Commons
Riccardo Sarzani, Matteo Landolfo,

Chiara Di Pentima

et al.

Frontiers in Medicine, Journal Year: 2024, Volume and Issue: 11

Published: April 8, 2024

Obesity is a multifactorial chronic disease characterized by an excess of adipose tissue, affecting people all ages. In the last 40 years, incidence overweight and obesity almost tripled worldwide. The accumulation “visceral” tissue increases with aging, leading to several cardio-metabolic consequences: from increased blood pressure overt arterial hypertension, insulin-resistance type 2 diabetes mellitus (T2DM), dyslipidemia, kidney (CKD), obstructive sleep apnea. increasing use innovative drugs, namely glucagon-like peptide-1 receptor agonists (GLP1-RA) sodium-glucose cotransporter-2 inhibitors (SGLT2-i), changing management its related cardiovascular complications significantly. These first considered only for T2DM treatment, are now used in patients visceral adiposity or obese patients, as no longer just risk factor but critical condition at basis common metabolic, cardiovascular, renal diseases. An adipocentric vision approach should become cornerstone integrated reducing avoiding onset obesity-related multiple factors their clinical complications. According recent progress basic research on adiposity, this narrative review aims contribute novel focusing pathophysiological therapeutic insights.

Language: Английский

Citations

6

Thirty Obesity Myths, Misunderstandings, and/or Oversimplifications: An Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022 DOI Creative Commons
Harold Bays, Angela Golden, Justin Tondt

et al.

Obesity Pillars, Journal Year: 2022, Volume and Issue: 3, P. 100034 - 100034

Published: Aug. 10, 2022

This Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) is intended to provide clinicians an overview of 30 common obesity myths, misunderstandings, and/or oversimplifications. The scientific support for this CPS based upon published citations, clinical perspectives OMA authors, and peer review by the leadership. discusses oversimplifications, utilizing referenced publications such as integrative use other CPSs help explain applicable physiology/pathophysiology. on oversimplifications one a series designed assist in care patients with disease obesity. Knowledge underlying science may medicine clinician improve

Language: Английский

Citations

26

Translational Research on Bee Pollen as a Source of Nutrients: A Scoping Review from Bench to Real World DOI Open Access

Rachid Kacemi,

María G. Campos

Nutrients, Journal Year: 2023, Volume and Issue: 15(10), P. 2413 - 2413

Published: May 22, 2023

The emphasis on healthy nutrition is gaining a forefront place in current biomedical sciences. Nutritional deficiencies and imbalances have been widely demonstrated to be involved the genesis development of many world-scale public health burdens, such as metabolic cardiovascular diseases. In recent years, bee pollen emerging scientifically validated candidate, which can help diminish conditions through nutritional interventions. This matrix being extensively studied, has proven very rich well-balanced nutrient pool. this work, we reviewed available evidence interest source. We mainly focused richness nutrients its possible roles main pathophysiological processes that are directly linked imbalances. scoping review analyzed scientific works published last four focusing clearest inferences perspectives translate cumulated experimental preclinical into clinically relevant insights. promising uses for malnutrition, digestive health, disorders, other bioactivities could helpful readjust homeostasis (as it also true case anti-inflammatory or anti-oxidant needs), well benefits diseases, were identified. knowledge gaps identified, along with practical challenges hinder establishment fructification these uses. A complete data collection made major range botanical species allows more robust clinical information.

Language: Английский

Citations

15

Health Benefits Beyond the Scale: The Role of Diet and Nutrition During Weight Loss Programmes DOI Open Access
F Contreras, Werd Al‐Najim, Carel W. le Roux

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(21), P. 3585 - 3585

Published: Oct. 22, 2024

Introduction: Obesity management strategies such as caloric restriction, very-low-calorie diets (VLCDs), and meal replacements can lead to moderate short-term weight loss. However, many patients face significant challenges in maintaining these results. Personalized interventions, including behavioral counseling physical activity, have been shown improve long-term adherence success. Current clinical guidelines emphasize the pivotal role of dietitians enhancing patient outcomes through nutritional therapy. When combined with pharmacotherapy bariatric surgery, focus shifts from mere loss broader health improvements. Methods: This review explores evolving obesity management, advocating for a shift weight-centric approach more holistic model that prioritizes overall gains. Key areas interest include dietetic interventions’ impact on metabolic health, cardiovascular function, gut microbiome balance, inflammation, psychological well-being. Results: Dietetic interventions provide improvements beyond These enhanced better reduced improved sleep quality, mental well-being, quality life. By focusing non-scale victories insulin sensitivity, lipid profiles, play crucial driving success management. highlight need comprehensive view Conclusions: The is expanding encompass individualized approach. Moving reduction, this paradigm promotes long-term, patient-centered address multifactorial nature obesity. combining dietary changes regular activity support, contribute sustained improvements, treating chronic, complex disease.

Language: Английский

Citations

6

Safety of Glucagon-Like Peptide-1 Receptor Agonists: A Real-World Study Based on the US FDA Adverse Event Reporting System Database DOI

Tingxi Wu,

Yang Zhang,

Yanfeng Shi

et al.

Clinical Drug Investigation, Journal Year: 2022, Volume and Issue: 42(11), P. 965 - 975

Published: Sept. 30, 2022

Language: Английский

Citations

20