Electrically-Transduced Chemical Sensors Based on Two-Dimensional Nanomaterials

Chemical Reviews, Journal Year: 2019, Volume and Issue: 119(1), P. 478 - 598

Published: Jan. 3, 2019

Electrically–transduced sensors, with their simplicity and compatibility standard electronic technologies, produce signals that can be efficiently acquired, processed, stored, analyzed. Two dimensional (2D) nanomaterials, including graphene, phosphorene (BP), transition metal dichalcogenides (TMDCs), others, have proven to attractive for the fabrication of high–performance electrically-transduced chemical sensors due remarkable physical properties originating from 2D structure. This review highlights advances in sensing rely on materials. The structural components such are described, underlying operating principles different types architectures discussed. features, properties, surface chemistry nanostructures dictate performance reviewed. Key application materials, both a historical analytical perspective, summarized four groups analytes: gases, volatile compounds, ions, biomolecules. is discussed context molecular design, structure–property relationships, device technology. outlook challenges opportunities nanomaterials future development also presented.

Language: Английский

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Detection of unamplified target genes via CRISPR–Cas9 immobilized on a graphene field-effect transistor

Nature Biomedical Engineering, Journal Year: 2019, Volume and Issue: 3(6), P. 427 - 437

Published: March 25, 2019

Language: Английский

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The Era of Digital Health: A Review of Portable and Wearable Affinity Biosensors

Advanced Functional Materials, Journal Year: 2019, Volume and Issue: 30(29)

Published: Nov. 14, 2019

Abstract Digital health facilitated by wearable/portable electronics and big data analytics holds great potential in empowering patients with real‐time diagnostics tools information. The detection of a majority biomarkers at trace levels body fluids using mobile (mHealth) devices requires bioaffinity sensors that rely on “bioreceptors” for specific recognition. Portable point‐of‐care testing (POCT) have demonstrated their broad utility diverse applications ranging from monitoring to disease diagnosis management. In addition, flexible stretchable electronics‐enabled wearable platforms emerged the past decade as an interesting approach ambulatory collection data. Herein, technological advancements mHealth evolved laboratory assays portable POCT devices, electronics, are synthesized. involved recognition events affinity biosensors enabled bioreceptors (e.g., antibodies, DNAs, aptamers, molecularly imprinted polymers) discussed along transduction mechanisms electrochemical optical) system‐level integration technologies. Finally, outlook field is provided key bottlenecks overcome identified, order achieve new sensing paradigm platforms.

Language: Английский

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Metal oxide nanostructures for sensor applications

Semiconductor Science and Technology, Journal Year: 2019, Volume and Issue: 34(4), P. 043001 - 043001

Published: Jan. 24, 2019

Human health, environmental protection and safety are just a few examples of humankind's current main concerns, that drive the scientific community to develop sensors able monitor precisely provide alerts possible harm in real time. Over years, semiconductor metal oxide-based materials have been extensively employed as several applications. They particular interest at nanometer scale, since it is widely known smaller crystallite size enhances sensor's performance. Moreover, these highly appealing they can be produced by low-cost wet-chemical synthesis routes general nontoxic, earth abundant low cost. This manuscript reviews recent developments nanostructured oxide ranging from gas humidity sensors, including ultraviolet biosensors. Sensors based on zinc (ZnO), titanium dioxide (TiO2), tungsten trioxide (WO3), copper (CuO Cu2O), tin (SnO SnO2) vanadium (VO2 V2O5), either nanoparticles or continuous films layers, described. Their sensing properties correlated size, shape, presence defects doping elements, amongst other relevant parameters. Various techniques methods fabricating addressed. The review concludes with novel approaches for functionalization future perspectives sensor developments.

Language: Английский

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From Diagnosis to Treatment: Recent Advances in Patient-Friendly Biosensors and Implantable Devices

ACS Nano, Journal Year: 2021, Volume and Issue: 15(2), P. 1960 - 2004

Published: Feb. 3, 2021

Patient-friendly medical diagnostics and treatments have been receiving a great deal of interest due to their rapid cost-effective health care applications with minimized risk infection, which has the potential replace conventional hospital-based procedures. In particular, integration recently developed materials into devices allows development point-of-care (POC) sensing platforms implantable special functionalities. this review, recent advances in biosensors for patient-friendly diagnosis treatment are discussed. Comprehensive analysis portable wearable biosensing monitoring disease is provided, including topics such as selection, device structure integration, biomarker detection strategies. Moreover, specific challenges related each biological fluid biosensor-based POC presented. Also, devices, wireless communication strategies, Furthermore, various surgical approaches reviewed, minimally invasive insertion mounting, vivo electrical optical modulations, post-operation monitoring. Finally, future perspectives toward provided.

Language: Английский

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Impedance-Based Detection of Bacteria

Chemical Reviews, Journal Year: 2018, Volume and Issue: 119(1), P. 700 - 726

Published: Dec. 17, 2018

Pathogenic bacteria have always posed one of the most serious threats to public health, and continue be especially dangerous with rise in antibiotic resistance. The prevalence these infectious agents necessitates rapid, point-of-care sensors for their detection, identification, monitoring. Electrochemical are promising low-cost monitoring bacterial growth detection specific microbial species due consistency ease-of-use impedance measurements. Though commercialization is currently limited, they offer significant promise detecting pathogens from real-world environments.

Language: Английский

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Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples

Nature Biomedical Engineering, Journal Year: 2022, Volume and Issue: 6(3), P. 276 - 285

Published: Feb. 7, 2022

Language: Английский

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Review—Field-Effect Transistor Biosensing: Devices and Clinical Applications

ECS Journal of Solid State Science and Technology, Journal Year: 2018, Volume and Issue: 7(7), P. Q3196 - Q3207

Published: Jan. 1, 2018

Biosensor research has been addressed as an interested field recently. Within different kinds of developed biosensing technologies, field-effect transistor (FET) based biosensors stand out due to their attractive features, such ultra-sensitivity detection, mass-production capability, and low-cost manufacturing. To promote understandings the FET technology, in this review, its sensing mechanism is introduced, well major FET-based devices: ion sensitive (ISFET), silicon nanowire, organic FET, graphene compound-semiconductor FET. In addition devices, clinical applications, cardiovascular diseases (CVDs), cancers, diabetes, HIV, DNA sequence, are also reviewed. end, several critical challenges technology discussed envision next steps healthcare technologies.

Language: Английский

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Recent advances and challenges in electrochemical biosensors for emerging and re-emerging infectious diseases

Journal of Electroanalytical Chemistry, Journal Year: 2020, Volume and Issue: 878, P. 114596 - 114596

Published: Aug. 25, 2020

Language: Английский

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Recent Advances and Progress in Development of the Field Effect Transistor Biosensor: A Review

Journal of Electronic Materials, Journal Year: 2019, Volume and Issue: 48(12), P. 7635 - 7646

Published: Oct. 11, 2019

Language: Английский

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