Microfluidic Point-of-Care (POC) Devices in Early Diagnosis: A Review of Opportunities and Challenges

Sensors, Journal Year: 2022, Volume and Issue: 22(4), P. 1620 - 1620

Published: Feb. 18, 2022

The early diagnosis of infectious diseases is critical because it can greatly increase recovery rates and prevent the spread such as COVID-19; however, in many areas with insufficient medical facilities, timely detection challenging. Conventional testing methods require specialized laboratory equipment well-trained operators, limiting applicability these tests. Microfluidic point-of-care (POC) rapidly detect at low cost. This technology could be used to underdeveloped reduce effects disease improve quality life areas. review details microfluidic POC its applications. First, concept devices discussed. We then describe applications for diseases, cardiovascular tumors (cancer), chronic discuss future incorporation into wearable telemedicine. Finally, concludes by analyzing present state field, suggestions are made. intended call attention status treatment encourage researchers microfluidics develop standards devices.

Language: Английский

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Advances in Novel Nanomaterial-Based Optical Fiber Biosensors—A Review

Biosensors, Journal Year: 2022, Volume and Issue: 12(10), P. 843 - 843

Published: Oct. 8, 2022

This article presents a concise summary of current advancements in novel nanomaterial-based optical fiber biosensors. The beneficial and biological properties nanomaterials, such as nanoparticle size-dependent signal amplification, plasmon resonance, charge-transfer capabilities, are widely used biosensing applications. Due to the biocompatibility bioreceptor combination, nanomaterials enhance sensitivity, limit detection, specificity, response time sensing probes, well signal-to-noise ratio optic platforms. has established practical method for improving performance With aforementioned outstanding nanomaterial properties, development biosensors been efficiently promoted. paper reviews application numerous field provides brief explanation mechanism.

Language: Английский

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Recent Trends in SERS-Based Plasmonic Sensors for Disease Diagnostics, Biomolecules Detection, and Machine Learning Techniques

Biosensors, Journal Year: 2023, Volume and Issue: 13(3), P. 328 - 328

Published: Feb. 27, 2023

Surface-enhanced Raman spectroscopy/scattering (SERS) has evolved into a popular tool for applications in biology and medicine owing to its ease-of-use, non-destructive, label-free approach. Advances plasmonics instrumentation have enabled the realization of SERS’s full potential trace detection biomolecules, disease diagnostics, monitoring. We provide brief review on recent developments SERS technique biosensing applications, with particular focus machine learning techniques used same. Initially, article discusses need plasmonic sensors advantage over existing techniques. In later sections, are organized as SERS-based diagnosis focusing cancer identification respiratory diseases, including SARS-CoV-2 detection. then discuss progress sensing microorganisms, such bacteria, detecting biohazardous materials view homeland security. At end article, we (a) identification, (b) classification, (c) quantification applications. The covers work from 2010 onwards, language is simplified suit needs interdisciplinary audience.

Language: Английский

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Platinum Diselenide and Graphene-Based Refractive Index Sensor for Cancer Detection

Plasmonics, Journal Year: 2023, Volume and Issue: 19(2), P. 953 - 962

Published: Sept. 14, 2023

Language: Английский

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Novel manufacturing systems for cancer diagnosis using ultra-sensitive photonic crystal fiber biosensor with dual-functionalized aptamer-nanocavity

Microsystem Technologies, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 12, 2024

Language: Английский

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A Novel Method for Detecting Genetic Biomarkers in Blood-based Liquid Biopsies Using Surface Plasmon Resonance Imaging and Magnetic Beads Shows Promise in Cancer Diagnosis and Monitoring

Talanta, Journal Year: 2025, Volume and Issue: unknown, P. 127543 - 127543

Published: Jan. 1, 2025

Language: Английский

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Advances in Extracellular Vesicle Nanotechnology for Precision Theranostics

Advanced Science, Journal Year: 2022, Volume and Issue: 10(3)

Published: Nov. 14, 2022

Abstract Extracellular vesicles (EVs) have increasingly been recognized as important cell surrogates influencing many pathophysiological processes, including cellular homeostasis, cancer progression, neurologic disease, and infectious disease. These behaviors enable EVs broad application prospects for clinical in disease diagnosis treatment. Many studies suggest that are superior to conventional synthetic carriers terms of drug delivery circulating biomarkers early diagnosis, opening up new frontiers modern theranostics. Despite these potential, containing diverse components, such nucleic acids, proteins, metabolites highly heterogeneous small size. The limitation preparatory, engineering analytical technologies poses technical barriers translation. This article aims at present a critical overview emerging field biomedical applications challenges involved their clinic translations. current methods isolation identification discussed. Additionally, strategies developed enhance scalable production improved cargo loading well tumor targeting presented. potential EVs, particularly different origins the next generation diagnostic treatment platforms, clarified.

Language: Английский

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Monitoring and detection of antibiotic residues in animal derived foods: Solutions using aptamers

Trends in Food Science & Technology, Journal Year: 2022, Volume and Issue: 125, P. 200 - 235

Published: May 17, 2022

Language: Английский

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Current trends in blood biomarker detection and imaging for Alzheimer’s disease

Biosensors and Bioelectronics, Journal Year: 2022, Volume and Issue: 210, P. 114278 - 114278

Published: April 13, 2022

Language: Английский

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Surface plasmon resonance biosensor sensitivity improvement employing of 2D materials and BaTiO3 with bimetallic layers of silver

Journal of Materials Science Materials in Electronics, Journal Year: 2023, Volume and Issue: 34(6)

Published: Feb. 1, 2023

Language: Английский

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