Journal of Agricultural and Food Chemistry,
Journal Year:
2023,
Volume and Issue:
71(51), P. 20793 - 20800
Published: Dec. 14, 2023
Highly
sensitive
and
reliable
detection
of
β-adrenergic
agonists
is
especially
necessary
due
to
the
illegal
abuse
growth-promoting
feed
additives.
Here,
we
develop
a
novel
surface
plasmon
resonance/surface-enhanced
Raman
scattering
(SPR/SERS)
dual-mode
plasmonic
sensor
based
on
core–satellite
nanoassemblies
for
highly
ractopamine
(RAC).
The
addition
RAC
results
in
decomposition
consequently
changes
Rayleigh
color
dark-field
microscopy
(DFM)
images
intensity
SERS
spectra.
excellent
sensitivity,
specificity,
uniformity
this
strategy
were
confirmed
by
detecting
various
complex
media
farm-to-table
chain,
limit
(LOD)
was
0.03
ng/mL
an
aqueous
solution.
In
particular,
convenient
access
livestock
sewage
not
only
ensures
animal
welfare
but
also
provides
great
convenience
market
regulation
β-agonists.
success
our
on-site
with
portable
device
promises
application
prospects
β-agonist
detection.
Biophysical Reviews,
Journal Year:
2023,
Volume and Issue:
15(2), P. 199 - 221
Published: April 1, 2023
Abstract
Raman
spectroscopy
offers
the
potential
for
fingerprinting
biological
molecules
at
ultra-low
concentration
and
therefore
has
detection
of
viruses.
Here
we
review
various
techniques
employed
investigation
Different
are
discussed
including
conventional
spectroscopy,
surface-enhanced
tweezer,
tip-enhanced
Spectroscopy,
coherent
anti-Stokes
scattering.
Surface-enhanced
scattering
can
play
an
essential
role
in
viral
by
multiplexing
nanotechnology,
microfluidics,
machine
learning
ensuring
spectral
reproducibility
efficient
workflow
sample
processing
detection.
The
application
these
to
diagnose
SARS-CoV-2
virus
is
also
reviewed.
Graphical
abstract
Journal of Genetic Engineering and Biotechnology,
Journal Year:
2024,
Volume and Issue:
22(3), P. 100400 - 100400
Published: July 26, 2024
Aptamers
are
single-stranded
oligonucleotide
sequences
capable
of
binding
to
specific
ligands
with
high
affinity.
In
this
manner,
they
like
antibodies
but
have
advantages
such
as
lower
manufacturing
costs,
immunogenicity,
fewer
batch-to-batch
differences,
a
longer
shelf
life,
tolerance
different
molecular
milieus,
and
greater
number
potential
targets.
Due
their
special
features,
been
used
in
drug
delivery,
biosensor
technology,
therapy,
diagnostics.
The
methodology
that
allowed
its
production
was
the
"Systematic
Evolution
Ligands
by
Exponential
enrichment"
(SELEX).
Unfortunately,
traditional
protocol
is
time-consuming
laborious.
Therefore,
numerous
variants
considerable
optimization
steps
developed,
nonetheless,
there
still
challenges
achieving
real
applications
clinical
field.
Among
them,
control
vivo
activities,
fast
renal
filtration,
degradation
nucleases
toxicity
testing.
This
review
focuses
on
current
technologies
based
SELEX,
critical
factors
for
successful
aptamer
selection,
upcoming
biomedical
biotechnological
applications.
Water Research,
Journal Year:
2025,
Volume and Issue:
unknown, P. 123484 - 123484
Published: March 1, 2025
Wastewater-based
epidemiological
(WBE)
surveillance
has
emerged
as
a
crucial
tool
for
monitoring
infectious
diseases
within
communities.
However,
its
broader
application
is
frequently
constrained
by
the
high
costs,
labor-intensive
processes,
and
extended
timeframes
required
sample
collection,
transportation,
processing.
Aptamer-based
biosensors
offer
promising
alternative,
leveraging
specific
binding
properties
of
aptamers
to
biomolecules
on-site
rapid
quantification
disease
biomarkers
in
wastewater.
This
review
systematically
evaluates
recent
advancements
aptamer-based
detection
key
pathogens,
including
influenza
viruses,
SARS-CoV-2,
norovirus,
wastewater
matrices.
The
discussion
encompasses
technical
stability
reliability
signal
transmission
associated
with
these
biosensors,
well
current
challenges
faced
real-world
implementation.
Noteworthy
progress
been
made
development
WBE,
achieving
limits
low
femtomolar
(fM)
levels
buffer
linear
dynamic
ranges
extending
up
five
orders
magnitude
viruses
such
SARS-CoV-2.
Despite
this
progress,
considerable
hurdles
remain
be
addressed
before
technologies
can
effectively
deployed
practical
settings,
especially
complex
environments.
Key
factors
affecting
performance
include
matrix
interference,
environmental
variability,
diminished
both
viral
targets
aptamer-target
interactions
not
only
highlights
but
also
outlines
potential
avenues
future
research
aimed
at
enhancing
functionality
applicability
ultimately
contributing
more
effective
public
health
strategies.
Biosensors,
Journal Year:
2023,
Volume and Issue:
13(8), P. 822 - 822
Published: Aug. 15, 2023
Virus-related
infectious
diseases
are
serious
threats
to
humans,
which
makes
virus
detection
of
great
importance.
Traditional
virus-detection
methods
usually
suffer
from
low
sensitivity
and
specificity,
time-consuming,
have
a
high
cost,
etc.
Recently,
DNA
biosensors
based
on
nanotechnology
shown
potential
in
detection.
nanotechnology,
specifically
tiles
aptamers,
has
achieved
atomic
precision
nanostructure
construction.
Exploiting
the
programmable
nature
nanostructures,
researchers
developed
nanobiosensors
that
outperform
traditional
methods.
This
paper
reviews
history
it
briefly
describes
Baltimore
classification
virology.
Moreover,
advance
by
using
is
discussed
detail
compared
with
Finally,
challenges
faced
summarized,
perspective
future
development
also
provided.
Biosensors,
Journal Year:
2024,
Volume and Issue:
14(3), P. 146 - 146
Published: March 15, 2024
The
global
challenges
posed
by
the
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
pandemic
have
underscored
critical
importance
of
innovative
and
efficient
control
systems
for
addressing
future
pandemics.
most
effective
way
to
is
rapidly
suppress
spread
virus
through
early
detection
using
a
rapid,
accurate,
easy-to-use
diagnostic
platform.
In
biosensors
that
use
bioprobes,
binding
affinity
molecular
recognition
elements
(MREs)
primary
factor
determining
dynamic
range
sensing
Furthermore,
sensitivity
relies
mainly
on
bioprobe
quality
with
sufficient
functionality.
This
comprehensive
review
investigates
aptamers
nanobodies
recently
developed
as
advanced
MREs
SARS-CoV-2
therapeutic
applications.
These
bioprobes
might
be
integrated
into
organic
bioelectronic
materials
devices,
promising
enhanced
specificity.
offers
valuable
insights
advancing
biosensing
technologies
infectious
disease
diagnosis
treatment
new
bioprobes.
