Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 149, P. 104556 - 104556
Published: May 24, 2024
Language: Английский
Molecular Biotechnology, Journal Year: 2023, Volume and Issue: 66(3), P. 378 - 401
Published: May 11, 2023
Language: Английский
Citations
30
ACS Applied Bio Materials, Journal Year: 2023, Volume and Issue: 6(10), P. 3959 - 3983
Published: Sept. 12, 2023
Applications of nanotechnology have increased the importance research and nanocarriers, which revolutionized method drug delivery to treat several diseases, including cancer, in past few years. Cancer, one world's fatal has drawn scientists' attention for its multidrug resistance various chemotherapeutic drugs. To minimize side effects agents on healthy cells develop technological advancement systems, scientists developed an alternative approach delivering drugs at targeted site by integrating it inside nanocarriers like synthetic polymers, nanotubes, micelles, dendrimers, magnetic nanoparticles, quantum dots (QDs), lipid nano-biopolymeric substances, etc., shown promising results both preclinical clinical trials cancer management. Besides that, especially biopolymeric received much from researchers due their cost-effectiveness, biodegradability, treatment efficacy, ability target crossing blood-brain barrier. This review emphasizes fabrication processes, therapeutic theragnostic applications, different targeting vitro vivo, conclude with challenges opportunities future exploration using onco-therapy improved availability reduced toxicity.
Language: Английский
Citations
29
ACS Biomaterials Science & Engineering, Journal Year: 2024, Volume and Issue: 10(4), P. 1946 - 1965
Published: March 1, 2024
Various nanomaterials have recently become fascinating tools in cancer diagnostic applications because of their multifunctional and inherent molecular characteristics that support efficient diagnosis image-guided therapy. Zein nanoparticles are a protein derived from maize. It belongs to the class prolamins possessing spherical structure with conformational properties similar those conventional globular proteins like ribonuclease insulin. gained massive interest over past couple years owing natural hydrophilicity, ease functionalization, biodegradability, biocompatibility, thereby improving oral bioavailability, nanoparticle targeting, prolonged drug administration. Thus, zein becoming promising candidate for precision delivery. This review highlights clinical significance applying nanosystems theragnostic─moreover, role delivery, anticancer agents, gene Finally, difficulties potential uses these NPs treatment detection discussed. will pave way researchers develop theranostic strategies medicine utilizing nanosystems.
Language: Английский
Citations
17
Physics of Fluids, Journal Year: 2024, Volume and Issue: 36(3)
Published: March 1, 2024
Fluid mechanics is a branch of physics that focuses on the study behavior and laws motion fluids, including gases, liquids, plasmas. The Yu–Toda–Sasa–Fukuyama equation, class Kadomtsev–Petviashvili type equations, significant integrable model with applications in fluids other fields. In this paper, we breather soliton solutions generalized (3 + 1)-dimensional YTSF equation. By utilizing Hirota bilinear method Painlevé analysis, construct form trigonometric hyperbolic functions analyze interaction between waves graphically. We consider characteristics wave distribution along characteristic lines to obtain distance each angle generated, which beneficial for understanding ocean superposition effect. Additionally, examine dynamic wave, such as amplitude, velocity, period, shape, position, width, phase. Furthermore, investigate effects system parameters solitons breathers.
Language: Английский
Citations
16
Discover Nano, Journal Year: 2024, Volume and Issue: 19(1)
Published: Aug. 5, 2024
Abstract Research into the anticancer activity of quantum-sized carbon dots (CDs) has emerged as a promising avenue in cancer research. This CDs delves opportunities and challenges associated with harnessing potential these nanostructures for combating cancer. Quantum-sized dots, owing to their unique physicochemical properties, exhibit distinct advantages therapeutic agents. Opportunities lie tunable size, surface functionalization capabilities, biocompatibility, enabling targeted drug delivery imaging cells. However, we include challenges, comprehensive understanding underlying mechanisms, toxicity concerns, optimization synthesis methods enhanced efficacy. A succinct summary state research this area is given review, emphasizing exciting possibilities ongoing utilizing novel strategy treatment.
Language: Английский
Citations
12
Foods, Journal Year: 2024, Volume and Issue: 13(23), P. 3886 - 3886
Published: Dec. 1, 2024
Foodborne pathogens are microorganisms that cause illness through contamination, presenting significant risks to public health and food safety. This review explores the metabolites produced by these pathogens, including toxins secondary metabolites, their implications for human health, particularly concerning cancer risk. We examine various such as Salmonella sp., Campylobacter Escherichia coli, Listeria monocytogenes, detailing specific of concern carcinogenic mechanisms. study discusses analytical techniques detecting chromatography, spectrometry, immunoassays, along with challenges associated detection. covers effective control strategies, processing techniques, sanitation practices, regulatory measures, emerging technologies in pathogen control. manuscript considers broader highlighting importance robust policies, awareness, education. identifies research gaps innovative approaches, recommending advancements detection methods, preventive policy improvements better manage foodborne metabolites.
Language: Английский
Citations
12
Deleted Journal, Journal Year: 2024, Volume and Issue: 6(9)
Published: Aug. 23, 2024
Abstract The potential threat posed by disease outbreaks to diagnostic instruments demands the development of more effective biosensor technologies counteract risks. Diseases like SARS-CoV-2, Ebola, malaria, cholera, and many have demonstrated beyond limits health care that new advancements are required for early detection diagnosis. rising number diseases has led an increasing demand biosensors quicker utilize in healthcare settings. A incorporated with microfluidic chips offers improved compared traditional or classical biosensors. Microfluidic improve performance allowing automation, mixing, separation, throughput processing, transport analytes desired reactors. a chip sensitivity, easy operation can use small volumes samples process results. effectiveness depends also on materials used its fabrication there which reviewed this work. This paper reviews advantages enhance biosensors, fabricate chips, electrodes into time shortening processing at point service. work not previously addressed other including, integration cell-imprinted polymers sensors delved future outlook.
Language: Английский
Citations
11
Small, Journal Year: 2024, Volume and Issue: 20(23)
Published: Jan. 4, 2024
Abstract Acoustic microfluidic devices have advantages for diagnostic applications, therapeutic solutions, and fundamental research due to their contactless operation, simple design, biocompatibility. However, most acoustofluidic approaches are limited forming fixed acoustic patterns, or resolution. In this study,a detachable device is demonstrated employing miniature holograms create reconfigurable, flexible, high‐resolution fields in channels, where the introduction of a solid coupling layer makes these easy fabricate integrate. The application method generate flexible fields, including shapes, characters, arbitrarily rotated within demonstrated.
Language: Английский
Citations
10
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 495, P. 153036 - 153036
Published: June 13, 2024
Liquid-liquid systems play an important role in several industrial processes. Their separation efficiency determines the product purity and yield to a great extent. In recent years, there has been noticeable trend miniaturise liquid-liquid separators as process intensification strategy. However, adoption of miniaturised is lagging behind development technology. This review assesses latest research on five types separators: mini-hydrocyclones, helical separators, axial flow membrane filters microchannel separators. Special focus given geometric design, operating conditions, combination integration The advantages limitations these are highlighted, well challenges potential solutions for their at scale. analysis intended guide selection different scenarios bridge gaps between lab large-scale applications.
Language: Английский
Citations
9
Physical Review Fluids, Journal Year: 2025, Volume and Issue: 10(1)
Published: Jan. 29, 2025
Language: Английский
Citations
1