Industrial & Engineering Chemistry Research,
Journal Year:
2022,
Volume and Issue:
62(2), P. 841 - 866
Published: Dec. 29, 2022
Hydrogels
are
a
soft
material
that
undergoes
cross-linking
between
polymers
to
form
hydrophilic
three-dimensional
network.
In
fact,
similarity
body
tissue,
consistency,
biocompatibility,
and
elasticity,
impart
protagonic
role
of
hydrogel
be
applied
as
biomaterial.
response
external
cues,
stimuli-responsive
hydrogels
particularly
impactful,
enabling
remarkable
levels
control
over
properties.
They
can
endure
changes
in
swelling
behavior,
permeability,
network
structure,
mechanical
strength.
Nevertheless,
such
induce
single-cycle
or
reversible
transitions,
so
regain
their
initial
state
once
the
trigger
is
removed.
Recently,
polysaccharide-based
with
properties
resulted
developing
biomimetic
structures
for
widespread
biotechnological
application
owing
excellent
biodegradability,
nonimmunogenicity,
functional
properties,
ease
gelation,
derivatization.
This
review
will
initially
highlight
recent
advances
methods
chemistry
preparing
hydrogels.
Subsequently,
state-of-the-art
techniques
understand
structural,
chemical,
rheological
behavior
discussed.
Additionally,
responsiveness
polysaccharide
toward
diverse
stimuli
redox,
temperature,
light,
pH,
magnetism,
electricity,
etc.,
broad
spectrum
applications
described
detail.
also
attempts
address
lacunae
existing
future
perspectives.
Gels,
Journal Year:
2021,
Volume and Issue:
7(4), P. 255 - 255
Published: Dec. 9, 2021
Hydrogels
have
gained
a
lot
of
attention
with
their
widespread
use
in
different
industrial
applications.
The
versatility
the
synthesis
and
nature
precursor
reactants
allow
for
varying
range
hydrogels
mechanical
rheological
properties.
Understanding
behavior
relationship
between
chemical
structure
resulting
properties
is
crucial,
focus
this
review.
Specifically,
we
include
detailed
discussion
on
correlation
characteristics
possible
Different
tests
such
as
time,
temperature
frequency
sweep,
among
others,
are
described
results
those
reported.
most
prevalent
applications
also
discussed.
Bioactive Materials,
Journal Year:
2021,
Volume and Issue:
6(11), P. 3904 - 3923
Published: April 16, 2021
Natural
hydrogels
are
one
of
the
most
promising
biomaterials
for
tissue
engineering
applications,
due
to
their
biocompatibility,
biodegradability,
and
extracellular
matrix
mimicking
ability.
To
surpass
limitations
conventional
fabrication
techniques
recapitulate
complex
architecture
native
structure,
natural
being
constructed
using
novel
biofabrication
strategies,
such
as
textile
three-dimensional
bioprinting.
These
innovative
play
an
enormous
role
in
development
advanced
scaffolds
various
applications.
The
progress,
advantages,
shortcomings
emerging
highlighted
this
review.
Additionally,
applications
biofabricated
cardiac,
neural,
bone
discussed
well.
Frontiers in Chemistry,
Journal Year:
2021,
Volume and Issue:
8
Published: Feb. 4, 2021
Hydrogels
are
polymeric
three-dimensional
network
structures
with
high
water
content.
Due
to
their
superior
biocompatibility
and
low
toxicity,
hydrogels
play
a
significant
role
in
the
biomedical
fields.
categorized
by
composition
from
natural
polymers
synthetic
polymers.
To
meet
complicated
situation
applications,
suitable
host–guest
supramolecular
interactions
rationally
selected.
This
review
will
have
an
introduction
of
hydrogel
classification
based
on
formulation
molecules,
then
discussion
over
rational
design
intelligent
environmental
stimuli
such
as
temperature,
irradiation,
pH,
targeted
biomolecules.
Further,
applications
designed
smart
field
be
presented,
tissue
repair,
drug
delivery,
cancer
therapy.
Finally,
perspectives
challenges
outlined.
Pharmaceuticals,
Journal Year:
2022,
Volume and Issue:
15(3), P. 371 - 371
Published: March 18, 2022
Injectable
hydrogels
(IHs)
are
smart
biomaterials
and
the
most
widely
investigated
versatile
technologies,
which
can
be
either
implanted
or
inserted
into
living
bodies
with
minimal
invasion.
Their
unique
features,
tunable
structure
stimuli-responsive
biodegradation
properties
make
these
IHs
promising
in
many
biomedical
applications,
including
tissue
engineering,
regenerative
medicines,
implants,
drug/protein/gene
delivery,
cancer
treatment,
aesthetic
corrections
spinal
fusions.
In
this
review,
we
comprehensively
analyze
current
development
of
several
important
types
IHs,
all
those
that
have
received
FDA
approval,
under
clinical
trials
available
commercially
on
market.
We
also
structural
chemistry,
synthesis,
bonding,
chemical/physical
crosslinking
responsive
release
association
prospective
research.
Finally,
review
IHs'
associated
future
prospects,
hurdles,
limitations
challenges
their
development,
fabrication,
situ
applications
regulatory
affairs.
International Journal of Biomaterials,
Journal Year:
2022,
Volume and Issue:
2022, P. 1 - 16
Published: Nov. 7, 2022
Due
to
their
particular
water
absorption
capacity,
hydrogels
are
the
most
widely
used
scaffolds
in
biomedical
studies
regenerate
damaged
tissue.
Hydrogels
can
be
tissue
engineering
design
for
three-dimensional
cell
culture,
providing
a
novel
alternative
traditional
two-dimensional
culture
as
have
biomimetic
structure.
This
material
property
is
crucial
regenerative
medicine,
especially
nervous
system,
since
it
highly
complex
and
delicate
move
quickly
within
human
body
without
physically
disturbing
environment
possess
essential
biocompatible
properties,
well
ability
form
mimetic
scaffold
situ.
Therefore,
perfect
candidates
applications.
represent
potential
regenerating
lost
after
removing
brain
tumor
and/or
injuries.
reason
presents
them
an
exciting
physiological
problems,
such
injuries
central
system
neurodegenerative
disease.
Sustainable Food Technology,
Journal Year:
2024,
Volume and Issue:
2(5), P. 1297 - 1364
Published: Jan. 1, 2024
The
demand
for
sustainable
food
packaging
solutions
has
escalated
in
response
to
growing
environmental
concerns
and
consumer
preferences
eco-friendly
products.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
13(27)
Published: June 2, 2024
Abstract
Hydrogels
are
dynamically
evolving
3D
networks
composed
of
hydrophilic
polymer
scaffolds
with
significant
applications
in
the
healthcare
and
environmental
sectors.
Notably,
protein‐based
hydrogels
mimic
extracellular
matrix,
promoting
cell
adhesion.
Further
enhancing
proliferation
within
these
matrix‐metalloproteinase‐triggered
amino
acid
motifs.
Integration
cell‐friendly
modules
like
peptides
proteins
expands
hydrogel
functionality.
These
exceptional
properties
position
for
diverse
applications,
including
biomedicine,
biosensors,
remediation,
food
industry.
Despite
progress,
there
is
ongoing
research
to
optimize
biomedical
further.
Engineering
novel
favorable
characteristics
crucial
regulating
tissue
architecture
facilitating
ecological
remediation.
This
review
explores
synthesis,
physicochemical
properties,
biological
implications
various
types
their
extensive
biomedicine
It
elaborates
on
potential
bridging
gap
between
advancements
sector
solutions
issues.
