Integrated Biorefinery Design with Techno‐Economic and Life Cycle Assessment Tools in Polyhydroxyalkanoates Processing DOI Creative Commons
Vaibhav Vilas Andhalkar, Shin Ying Foong, Seng Hon Kee

et al.

Macromolecular Materials and Engineering, Journal Year: 2023, Volume and Issue: 308(11)

Published: July 9, 2023

Abstract To support and move toward a sustainable bioeconomy, the production of polyhydroxyalkanoates (PHAs) using renewable biomass has acquired more attention. However, expensive pretreatment low yield PHAs pose significant disadvantages in its large‐scale production. overcome such limitations, most recent advances metabolic engineering strategies used to develop high‐performance strains that are leading new manufacturing concept converting with co‐products as amino acids, proteins, biohydrogen, biosurfactants, various fine chemicals critically summarized. This review article presents comprehensive roadmap highlights integrated biorefinery strategies, lifecycle analysis, techno‐economic assessment for economic Finally, current future challenges must be addressed transfer this technology real‐world applications reviewed.

Language: Английский

PHA is not just a bioplastic! DOI
Helen Park,

Hongtao He,

Yan Xu

et al.

Biotechnology Advances, Journal Year: 2024, Volume and Issue: 71, P. 108320 - 108320

Published: Jan. 23, 2024

Language: Английский

Citations

62

Bacteria for Bioplastics: Progress, Applications, and Challenges DOI Creative Commons
Felipe M. de Souza, Ram K. Gupta

ACS Omega, Journal Year: 2024, Volume and Issue: 9(8), P. 8666 - 8686

Published: Feb. 12, 2024

Bioplastics are one of the answers that can point society toward a sustainable future. Under this premise, synthesis polymers with competitive properties using low-cost starting materials is highly desired factor in industry. Also, tackling environmental issues such as nonbiodegradable waste generation, high carbon footprint, and consumption nonrenewable resources some current concerns worldwide. The scientific community has been placing efforts into biosynthesis bacteria other microbes. These microorganisms be convenient reactors to consume food agricultural wastes convert them biopolymers inherently attractive biodegradability, biocompatibility, appreciable mechanical chemical properties. Such applied several fields packing, cosmetics, pharmaceutical, medical, biomedical, agricultural. Thus, intending elucidate science microbes produce polymers, review starts brief introduction bioplastics by describing their importance methods for production. second section dives regarding biochemical routes along advantages disadvantages. third covers main parameters influence biopolymers' Some applications comparison between obtained from petrochemical-based ones presented. Finally, discussion about future aspects challenges field provided should tackled wide application preparation bioplastics.

Language: Английский

Citations

28

Ectoine hyperproduction by engineered Halomonas bluephagenesis DOI
Qitiao Hu,

Simian Sun,

Zhongnan Zhang

et al.

Metabolic Engineering, Journal Year: 2024, Volume and Issue: 82, P. 238 - 249

Published: Feb. 23, 2024

Language: Английский

Citations

16

Synthetic biology of extremophiles: a new wave of biomanufacturing DOI
Jianwen Ye,

Yina Lin,

Xueqing Yi

et al.

Trends in biotechnology, Journal Year: 2022, Volume and Issue: 41(3), P. 342 - 357

Published: Dec. 17, 2022

Language: Английский

Citations

56

Metabolic engineering using acetate as a promising building block for the production of bio‐based chemicals DOI Creative Commons
Guiping Gong, Bo Wu,

Linpei Liu

et al.

Engineering Microbiology, Journal Year: 2022, Volume and Issue: 2(4), P. 100036 - 100036

Published: July 27, 2022

The production of biofuels and biochemicals derived from microbial fermentation has received a lot attention interest in light concerns about the depletion fossil fuel resources climatic degeneration. However, economic viability feedstocks for biological conversion remains barrier, urging researchers to develop renewable sustainable low-cost carbon sources future bioindustries. Owing numerous advantages, acetate been regarded as promising feedstock targeting acetyl-CoA-derived chemicals. This review aims highlight potential building block industrial biotechnology bio-based chemicals with metabolic engineering. Different alternative approaches routes comprised lignocellulosic biomass, waste streams, C1 gas generation are briefly described evaluated. Then, thorough explanation pathway biotechnological conversion, cellular transport, toxin tolerance is described. Particularly, current developments engineering manufacture summarized detail, various cell factories strategies proposed improve assimilation enhance product formation. Challenges development well eventually shown. provides an overview status utilization proves great biotechnology.

Language: Английский

Citations

46

Application of extremophile cell factories in industrial biotechnology DOI

Yuzhou Wang,

Jingyi Qian, Tian‐Qiong Shi

et al.

Enzyme and Microbial Technology, Journal Year: 2024, Volume and Issue: 175, P. 110407 - 110407

Published: Jan. 30, 2024

Language: Английский

Citations

13

Microbial Exopolysaccharides: Structure, Diversity, Applications, and Future Frontiers in Sustainable Functional Materials DOI Creative Commons
Claúdia Mouro, Ana P. Gomes, Isabel C. Gouveia

et al.

Polysaccharides, Journal Year: 2024, Volume and Issue: 5(3), P. 241 - 287

Published: July 13, 2024

Exopolysaccharides (EPSs) are a diverse class of biopolymers synthesized by microorganisms under environmental stress conditions, such as pH, temperature, light intensity, and salinity. They offer biodegradable environmentally friendly alternatives to synthetic polymers. Their structural versatility functional properties make them unique in various industries, including food, pharmaceuticals, biomedicine, cosmetics, textiles, petroleum, remediation. In this way, among the well-known EPSs, homopolysaccharides like dextran, bacterial cellulose, curdlan, levan, well heteropolysaccharides xanthan gum, alginate, gellan, kefiran, have found widespread applications numerous fields. However, recent attention has focused on potential role extremophile bacteria producing EPSs with novel unusual protective biological features extreme conditions. Therefore, review provides an overview commonly employed EPSs. It emphasizes their importance industries scientific endeavors while highlighting raised interest exploring compositions, structures, properties, underexplored functionalities. Nevertheless, despite benefits challenges persist. Hence, discusses these challenges, explores opportunities, outlines future directions, focusing impact developing innovative, sustainable, materials.

Language: Английский

Citations

12

Perspective on Lignin Conversion Strategies That Enable Next Generation Biorefineries DOI
Shilva Shrestha, Shubhasish Goswami, Deepanwita Banerjee

et al.

ChemSusChem, Journal Year: 2024, Volume and Issue: 17(16)

Published: April 26, 2024

Abstract The valorization of lignin, a currently underutilized component lignocellulosic biomass, has attracted attention to promote stable and circular bioeconomy. Successful approaches including thermochemical, biological, catalytic lignin depolymerization have been demonstrated, enabling opportunities for lignino‐refineries biorefineries. Although significant progress in made, this review describes unexplored chemical biological routes thereby contributes economically environmentally sustainable lignin‐utilizing This also highlights the integration identifies research gaps while recommending future directions scaling processes establish lignino‐chemical industry.

Language: Английский

Citations

11

A review on microbes mediated resource recovery and bioplastic (polyhydroxyalkanoates) production from wastewater DOI Creative Commons
Vishal Ahuja, Pankaj Singh, Chandan Mahata

et al.

Microbial Cell Factories, Journal Year: 2024, Volume and Issue: 23(1)

Published: July 1, 2024

Abstract Background Plastic is widely utilized in packaging, frameworks, and as coverings material. Its overconsumption slow degradation, pose threats to ecosystems due its toxic effects. While polyhydroxyalkanoates (PHA) offer a sustainable alternative petroleum-based plastics, their production costs present significant obstacles global adoption. On the other side, multitude of household industrial activities generate substantial volumes wastewater containing both organic inorganic contaminants. This not only poses threat but also presents opportunities get benefits from circular economy. Main body abstract Production bioplastics may be improved by using nutrients minerals feedstock for microbial fermentation. Strategies like feast-famine culture, mixed-consortia integrated processes have been developed PHA highly polluted with high loads. Various process parameters loading rate, content (volatile fatty acids), dissolved oxygen, operating pH, temperature critical roles accumulation biomass. Research advances are going on downstream recovery utilizing combination physical chemical (halogenated solvents, surfactants, green solvents) methods. review highlights recent developments upcycling resources into PHA, encompassing various strategies, processing methodologies, techno-economic analyses. Short conclusion Organic carbon nitrogen promising, cost-effective source producing bioplastic. Previous attempts focused enhancing productivity through optimizing culture systems growth conditions. However, despite technological progress, challenges persist, such low productivity, intricate processing, scalability issues, properties resulting PHA. Graphical

Language: Английский

Citations

11

Enrichment performance and salt tolerance of polyhydroxyalkanoates (PHAs) producing mixed cultures under different saline environments DOI

Qinxue Wen,

Zifan Wang, Baozhen Liu

et al.

Environmental Research, Journal Year: 2024, Volume and Issue: 251, P. 118722 - 118722

Published: March 16, 2024

Language: Английский

Citations

9