Molecular dynamics simulation techniques and their application to aroma compounds/cyclodextrin inclusion complexes: A review

Carbohydrate Polymers, Journal Year: 2023, Volume and Issue: 324, P. 121524 - 121524

Published: Oct. 31, 2023

Language: Английский

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Two-Phase Fermentation Systems for Microbial Production of Plant-Derived Terpenes

Molecules, Journal Year: 2024, Volume and Issue: 29(5), P. 1127 - 1127

Published: March 2, 2024

Microbial cell factories, renowned for their economic and environmental benefits, have emerged as a key trend in academic industrial areas, particularly the fermentation of natural compounds. Among these, plant-derived terpenes stand out significant class bioactive products. The large-scale production such terpenes, exemplified by artemisinic acid—a crucial precursor to artemisinin—is now feasible through microbial factories. In two-phase technology has been widely applied due its unique advantages. It facilitates situ product extraction or adsorption, effectively mitigating detrimental impact accumulation on cells, thereby significantly bolstering efficiency terpenes. This paper reviews latest developments system applications, focusing also discusses mechanisms influencing biosynthesis Moreover, we introduce some new techniques, currently unexplored terpene fermentation, with aim providing more thoughts explorations future applications technology. Lastly, discuss several challenges application systems, especially downstream processing.

Language: Английский

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Optimizing longifolene production in Yarrowia lipolytica via metabolic and protein engineering

Synthetic and Systems Biotechnology, Journal Year: 2025, Volume and Issue: 10(2), P. 433 - 441

Published: Jan. 22, 2025

Language: Английский

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Sniffing Out the Sustainable Future: The Renewability Revolution in Fragrance Chemistry**

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: 30(19)

Published: Feb. 15, 2024

In this review, the impact of transition from today's resource-wasting petrochemical economy towards a 100/100 renewable and biodegradable future is discussed with respect to fragrance families: "citrus", "green", "fruity", "floral", "floriental", "oriental", "woody", "chypre" "fougère". After benchmark data on ingredients usage, definitions biodegradation sustainability are given. Celebrating 150

Language: Английский

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Applications of Ene-Reductases in the Synthesis of Flavors and Fragrances

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 72(33), P. 18305 - 18320

Published: July 5, 2024

Flavors and fragrances (F&F) are interesting organic compounds in chemistry. These widely used the food, cosmetic, medical industries. Enzymatic synthesis exhibits several advantages over natural extraction chemical preparation, including a high yield, stable quality, mildness, environmental friendliness. To date, many oxidoreductases hydrolases have been to biosynthesize F&F. Ene-reductases (ERs) class of biocatalysts that can catalyze asymmetric reduction α,β-unsaturated offer superior specificity selectivity; therefore, ERs increasingly considered an ideal alternative their counterparts. This review summarizes research progress on use F&F past 20 years, achievements various scholars, differences similarities among findings, discussions future trends related ERs. We hope this inspire researchers promote development biotechnology industry.

Language: Английский

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Biosynthesis Progress of High-Energy-Density Liquid Fuels Derived from Terpenes

Microorganisms, Journal Year: 2024, Volume and Issue: 12(4), P. 706 - 706

Published: March 30, 2024

High-energy-density liquid fuels (HED fuels) are essential for volume-limited aerospace vehicles and could serve as energetic additives conventional fuels. Terpene-derived HED biofuel is an important research field green fuel synthesis. The direct extraction of terpenes from natural plants environmentally unfriendly costly. Designing efficient synthetic pathways in microorganisms to achieve high yields shows great potential the application terpene-derived This review provides overview current progress fuels, surveying terpene properties status biosynthesis. Additionally, we systematically summarize engineering strategies biosynthesizing terpenes, including mining synthases, optimizing metabolic cell-level optimization, such subcellular localization synthesis adaptive evolution. article will be helpful providing insight into better developing

Language: Английский

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Precision fermentation for producing food ingredients

Current Opinion in Food Science, Journal Year: 2024, Volume and Issue: 61, P. 101242 - 101242

Published: Nov. 12, 2024

Language: Английский

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Elucidating the biogenic transformation mechanisms of polyphenol and volatile compound metabolites in wild cherry wine co-fermentation by Hanseniaspora uvarum and Saccharomyces cerevisiae

LWT, Journal Year: 2025, Volume and Issue: unknown, P. 117420 - 117420

Published: Jan. 1, 2025

Language: Английский

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Untargeted metabolomics of Aloe volatiles: Implications in pathway enrichments for improved bioactivities

Heliyon, Journal Year: 2025, Volume and Issue: 11(3), P. e42268 - e42268

Published: Jan. 25, 2025

Language: Английский

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Unleashing potential of microbial biosynthesis of monoterpenes via enzyme and metabolic engineering

Biotechnology Advances, Journal Year: 2025, Volume and Issue: unknown, P. 108525 - 108525

Published: Feb. 1, 2025

Language: Английский

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