International Journal of Biological Macromolecules,
Journal Year:
2024,
Volume and Issue:
279, P. 134578 - 134578
Published: Aug. 8, 2024
Because
of
the
complex
symptoms
resulting
from
metabolic
dysfunction
in
wound
microenvironment
during
bacterial
infections,
along
with
necessity
to
combat
free
radicals,
achieving
prompt
and
thorough
healing
remains
a
significant
medical
challenge
that
has
yet
be
fully
addressed.
Moreover,
misuse
common
antibiotics
contributed
emergence
drug-resistant
bacteria,
underscoring
need
for
enhancements
practical
commonly
utilized
approach
treatment.
In
this
context,
hydrogel
dressings
based
on
biological
macromolecules
antibacterial
antioxidant
properties
present
promising
new
avenue
skin
treatment
due
their
multifunctional
characteristics.
Despite
considerable
potential
innovative
care,
comprehensive
research
these
is
still
insufficient.
Consequently,
development
advanced
macromolecule-based
hydrogels,
such
as
chitosan,
alginate,
cellulose,
hyaluronic
acid,
others,
been
primary
focus
study.
These
materials
have
enriched
various
agents
confer
attributes
purposes.
This
review
article
aims
offer
overview
latest
progress
field,
providing
critical
theoretical
basis
future
advancements
utilization
hydrogels
healing.
Materials Horizons,
Journal Year:
2021,
Volume and Issue:
8(6), P. 1618 - 1633
Published: Jan. 1, 2021
This
review
focuses
on
the
recent
progress
in
polydopamine
antibacterial
materials,
including
their
structural
and
functional
features,
preparation
strategies,
mechanisms,
biomedical
applications.
Journal of Hematology & Oncology,
Journal Year:
2023,
Volume and Issue:
16(1)
Published: Nov. 30, 2023
Inflammation
is
a
fundamental
defensive
response
to
harmful
stimuli,
but
the
overactivation
of
inflammatory
responses
associated
with
most
human
diseases.
Reactive
oxygen
species
(ROS)
are
class
chemicals
that
generated
after
incomplete
reduction
molecular
oxygen.
At
moderate
levels,
ROS
function
as
critical
signaling
molecules
in
modulation
various
physiological
functions,
including
responses.
However,
at
excessive
exert
toxic
effects
and
directly
oxidize
biological
macromolecules,
such
proteins,
nucleic
acids
lipids,
further
exacerbating
development
causing
Therefore,
designing
manufacturing
biomaterials
scavenge
has
emerged
an
important
approach
for
restoring
homeostasis,
limiting
protecting
host
against
damage.
This
review
systematically
outlines
dynamic
balance
production
clearance
under
conditions.
We
focus
on
mechanisms
by
which
regulate
cell
proteins
how
these
affect
inflammation.
Furthermore,
we
discuss
use
potential
currently
available-biomaterials
ROS,
agents
were
engineered
reduce
levels
blocking
generation,
chemically
reacting
or
catalytically
accelerating
clearance,
treatment
Finally,
evaluate
challenges
prospects
controlled
material
design
scavenging
biomaterials.
Chemical Society Reviews,
Journal Year:
2022,
Volume and Issue:
51(10), P. 4175 - 4198
Published: Jan. 1, 2022
Polyphenolic
materials
are
a
class
of
fascinating
and
versatile
bioinspired
for
biointerfacial
engineering.
In
particular,
due
to
the
presence
active
chemical
groups,
series
unique
physicochemical
properties
become
accessible
tunable
as-prepared
polyphenolic
platforms,
which
could
delicately
regulate
cell
activities
via
cell-material
contact-dependent
interactions.
More
interestingly,
polyphenols
also
affect
behaviors
contact-independent
manner,
arise
their
intrinsically
functional
characteristics
(e.g.,
antioxidant
photothermal
behaviors).
As
such,
comprehensive
understanding
on
relationship
between
material
desired
biomedical
applications,
as
well
underlying
mechanism
at
cellular
molecular
level
would
provide
design
principles
accelerate
lab-to-clinic
translation
platforms.
this
review,
we
firstly
give
brief
overview
hallmarks
governed
by
surrounding
cues,
followed
introduction
engineering
strategies.
Subsequently,
detailed
discussion
cell-polyphenols
interfacial
interaction
was
carefully
provided.
Lastly,
applications
were
elaborated.
We
believe
that
review
guidances
rational
multifunctional
extend
application
window.
Materials Today Bio,
Journal Year:
2021,
Volume and Issue:
11, P. 100124 - 100124
Published: June 1, 2021
Reactive
oxygen
species
(ROS)
mediate
multiple
physiological
functions;
however,
the
over-accumulation
of
ROS
causes
premature
aging
and/or
death
and
is
associated
with
various
inflammatory
conditions.
Nevertheless,
there
are
limited
clinical
treatment
options
that
currently
available.
The
good
news
owing
to
considerable
advances
in
nanoscience,
types
nanomaterials
unique
ROS-scavenging
abilities
influence
temporospatial
dynamic
behaviors
biological
systems
have
been
developed.
This
has
led
emergence
next-generation
nanomaterial-controlled
strategies
aimed
at
ameliorating
ROS-related
Accordingly,
herein
we
reviewed
recent
progress
research
on
nanotherapy
based
scavenging.
underlying
mechanisms
employed
emphasized.
Furthermore,
important
issues
developing
cross-disciplinary
nanomedicine-based
for
ROS-based
conditions
discussed.
Our
review
this
increasing
interdisciplinary
field
will
benefit
ongoing
studies
applications
nanomedicine
