Journal of Biomaterials Applications,
Journal Year:
2024,
Volume and Issue:
39(4), P. 377 - 395
Published: July 24, 2024
Hydrogels
have
several
characteristics,
including
biocompatibility,
physical
similarity
with
the
skin’s
extracellular
matrix,
and
regeneration
capacity.
Cell
migration
proliferation
are
facilitated
by
natural
polymers
such
as
gelatin
(Gel)
carboxymethyl
cellulose
(CMC).
Gelatin
dressing
acts
a
structural
framework
for
cell
into
wound
area,
stimulating
division
promoting
granulation
tissue
formation.
Omega-3
fatty
acids
from
fish
oil
may
prevent
infection
improve
healing
of
wounds
in
early
stages.
We
studied
preparation
containing
its
ability
to
heal
wounds.
In
this
study,
CMC-Gel
hydrogels
different
concentrations
were
investigated
full-thickness
After
fabrication
using
surfactant
(tween
20)
microemulsion
method
(oil
water),
various
tests
SEM,
Water
uptake
evaluation,
weight
loss,
viability,
blood
compatibility,
vivo
study
rat
cutaneous
modeling
during
14
days
performed
evaluate
properties
fabricated
hydrogels.
The
analysis
revealed
that
they
possess
porous
structures
interconnected
pores,
an
average
size
83.23
±
6.43
μm.
exhibited
swelling
capacity
up
60%
their
initial
within
24
h,
indicated
loss
measurements.
viability
MTT
technique
showed
no
cytotoxicity
was
observed
at
recommended
dosage,
however,
increasing
amount
omega-3
caused
hemolysis,
death,
inhibition
coagulation
activity.
An
adult
male
rats
model
greater
than
91%
improvement
primary
region
after
2
weeks
treatment.
Histological
demonstrated
hydrogels,
which
is
promising
approach
topical
skin
treatment
scar,
has
shown
efficacy
improving
repair
process
defect
site.
Giant,
Journal Year:
2024,
Volume and Issue:
19, P. 100301 - 100301
Published: June 6, 2024
The
global
community
has
encountered
numerous
challenges
concerning
environmental
sustainability,
encompassing
issues
like
waste
generation,
depletion
of
natural
resources,
air
pollution,
and
other
threats
to
human
well-being.
Consequently,
the
pursuit
an
eco-friendly
environment
emerged
as
a
critical
concern
in
recent
years.
Polysaccharides,
being
biopolymers,
have
garnered
significant
attention
owing
their
distinctive
properties
that
make
them
versatile
for
various
applications.
Numerous
sustainable
environmentally
friendly
polysaccharides,
such
chitosan,
cellulose,
starch,
hyaluronic
acid,
alginate,
inulin,
been
identified.
This
article
highlights
characteristics
renewable
categorization,
potential
contribute
sustainability.
It
introduces
extraction
methods
aimed
at
minimizing
chemical
pollution.
Through
careful
selection
diverse
polysaccharides
application
functionalization
techniques,
suggests
possibility
obtaining
suitable
superabsorbent
hydrogels,
appropriate
nanocomposites,
effective
scaffolds.
significance
utilizing
polysaccharide-based
materials
is
explored
detail,
emphasizing
exceptional
properties.
Additionally,
discusses
applications
polymers,
including
agriculture,
biomedicine,
food
packaging.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(8), P. 7473 - 7473
Published: April 18, 2023
Antibiotic
resistance
is
one
of
the
greatest
threats
to
global
health
and
food
security
today.
It
becomes
increasingly
difficult
treat
infectious
disorders
because
antibiotics,
even
newest
ones,
are
becoming
less
effective.
One
ways
taken
in
Global
Plan
Action
announced
at
World
Health
Assembly
May
2015
ensure
prevention
treatment
diseases.
In
order
do
so,
attempts
made
develop
new
antimicrobial
therapeutics,
including
biomaterials
with
antibacterial
activity,
such
as
polycationic
polymers,
polypeptides,
polymeric
systems,
provide
non-antibiotic
therapeutic
agents,
selected
biologically
active
nanoparticles
chemical
compounds.
Another
key
issue
preventing
from
contamination
by
developing
packaging
materials,
particularly
based
on
degradable
polymers
biocomposites.
This
review,
a
cross-sectional
way,
describes
most
significant
research
activities
conducted
recent
years
field
development
materials
polymer
composites
properties.
We
focus
natural
i.e.,
polysaccharides
which
present
mechanism
for
combating
many
highly
pathogenic
microorganisms.
also
attempt
use
this
knowledge
obtain
synthetic
similar
activity.
Gels,
Journal Year:
2023,
Volume and Issue:
9(7), P. 556 - 556
Published: July 7, 2023
Biopolymers
represent
a
great
resource
for
the
development
and
utilization
of
new
functional
materials
due
to
their
particular
advantages
such
as
biocompatibility,
biodegradability
non-toxicity.
“Intelligent
gels”
sensitive
different
stimuli
(temperature,
pH,
ionic
strength)
have
applications
in
many
industries
(e.g.,
pharmacy,
biomedicine,
food).
This
review
summarizes
research
efforts
presented
patent
non-patent
literature.
A
discussion
was
conducted
regarding
biopolymer-based
hydrogels
natural
proteins
(i.e.,
fibrin,
silk
fibroin,
collagen,
keratin,
gelatin)
polysaccharides
chitosan,
hyaluronic
acid,
cellulose,
carrageenan,
alginate).
In
this
analysis,
latest
advances
modification
characterization
advanced
biopolymeric
formulations
state-of-the-art
administration
drug
delivery,
wound
healing,
tissue
engineering
regenerative
medicine
were
addressed.
Gels,
Journal Year:
2024,
Volume and Issue:
10(4), P. 241 - 241
Published: April 1, 2024
This
manuscript
explores
self-healing
hydrogels
as
innovative
solutions
for
diverse
wound
management
challenges.
Addressing
antibiotic
resistance
and
tailored
care,
these
exhibit
promising
outcomes,
including
accelerated
closure
tissue
regeneration.
Advancements
in
multifunctional
with
controlled
drug
release,
antimicrobial
properties,
real-time
assessment
capabilities
signal
a
significant
leap
toward
patient-centered
treatments.
However,
challenges
such
scalability,
long-term
safety
evaluation,
variability
clinical
outcomes
persist.
Future
directions
emphasize
personalized
medicine,
manufacturing
innovation,
rigorous
evaluation
through
trials,
interdisciplinary
collaboration.
features
the
ongoing
pursuit
of
effective,
adaptable,
comprehensive
care
to
transform
medical
treatments
improve
patient
outcomes.
