International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(5), P. 2576 - 2576
Published: Feb. 22, 2024
The
work
presents
the
synthesis
of
a
series
linear
polyamidoamines
by
polycondensation
sebacoyl
dichloride
with
endogenous
polyamines:
putrescine,
spermidine,
spermine,
and
norspermidine—a
biogenic
polyamine
not
found
in
human
body.
During
carried
out
via
interfacial
reaction,
hydrophilic,
semi-crystalline
polymers
an
average
viscosity
molecular
weight
approximately
20,000
g/mol
melting
point
approx.
130
°C
were
obtained.
structure
composition
synthesized
confirmed
based
on
NMR
FTIR
studies.
cytotoxicity
tests
performed
fibroblasts
keratinocytes
showed
that
obtained
spermine
norspermidine
strongly
cytotoxic,
but
only
high
concentrations.
All
other
examined
did
show
even
at
concentrations
2000
µg/mL.
Simultaneously,
antibacterial
activity
polyamides
was
confirmed.
These
are
particularly
active
against
E.
Coli,
virtually
all
demonstrated
strong
inhibitory
effect
growth
cells
this
strain.
Antimicrobial
tested
polymer
strains
like
Staphylococcus
aureus,
epidermidis,
Pseudomonas
aeruginosa.
broadest
spectrum
bactericidal
action
from
which
contains
two
amino
groups
repeating
unit
chain.
can
be
used
as
material
for
forming
drug
carriers
biologically
compounds
form
micro-
nanoparticles,
especially
component
creams
ointments
dermatology
or
cosmetology.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(19), P. 10377 - 10377
Published: Sept. 26, 2024
Polymers
of
natural
origin,
such
as
representatives
various
polysaccharides
(e.g.,
cellulose,
dextran,
hyaluronic
acid,
gellan
gum,
etc.),
and
their
derivatives,
have
a
long
tradition
in
biomedical
applications.
Among
them,
the
use
chitosan
safe,
biocompatible,
environmentally
friendly
heteropolysaccharide
has
been
particularly
intensively
researched
over
last
two
decades.
The
potential
using
for
medical
purposes
is
reflected
its
unique
cationic
nature,
viscosity-increasing
gel-forming
ability,
non-toxicity
living
cells,
antimicrobial
activity,
mucoadhesiveness,
biodegradability,
well
possibility
chemical
modification.
intuitive
clay
minerals
treatment
superficial
wounds
known
traditional
medicine
thousands
years.
To
improve
efficacy
overcome
ubiquitous
bacterial
resistance,
beneficial
properties
utilized
preparation
chitosan–clay
mineral
bionanocomposites.
focus
this
review
on
composites
containing
with
montmorillonite
halloysite
minerals.
This
highlights
antibacterial
bionanocomposites
drug
delivery
topical
skin
infections
wound
healing.
Finally,
an
overview
preparation,
characterization,
possible
future
perspectives
related
to
these
advancing
applications
presented.
ACS Applied Materials & Interfaces,
Journal Year:
2023,
Volume and Issue:
15(43), P. 50344 - 50359
Published: Oct. 20, 2023
This
study
aims
to
prepare
natural
biomass-based
nonionic
antimicrobial
polymers
with
excellent
biocompatibility,
nonleachability,
activity,
and
polymer
miscibility.
Two
new
cellulose-based
(MIPA
MICA)
containing
many
terminal
indole
groups
were
synthesized
using
a
sustainable
one-pot
method.
The
structures
properties
of
the
characterized
nuclear
magnetic
resonance
hydrogen
spectroscopy
(1H
NMR),
infrared
(FTIR),
wide-angle
X-ray
diffractometry
(XRD),
thermogravimetric
analysis
(TGA),
differential
scanning
calorimetry
(DSC),
electron
microscopy
(SEM),
gel
chromatography
(GPC),
other
analytical
techniques.
results
showed
that
microcrystalline
cellulose
(MCC)
molecules
combined
derivatives
through
an
esterification
reaction
produce
MICA
MIPA.
crystallinity
prepared
MIPA
decreased
after
MCC
modification;
their
morphological
structure
changed
from
short
fibrous
granular
better
thermal
stability
solubility.
paper
diffusion
method
both
had
good
bactericidal
effects
against
two
common
pathogenic
bacteria
Escherichia
coli
(E.
coli,
inhibition
zone
diameters
>22
mm)
Staphylococcus
aureus
(S.
aureus,
>38
mm).
Moreover,
miscibility
biodegradable
poly(vinyl
alcohol)
(PVA),
miscible
composite
films
(PVA-MICA
PVA-MIPA)
phase
compatibility,
light
transmission,
(maximum
decomposition
temperature
>300
°C),
biological
cell
activity
(no
cytotoxicity),
mechanical
fracture
elongation
at
>390%).
Process Safety and Environmental Protection,
Journal Year:
2024,
Volume and Issue:
189, P. 1342 - 1367
Published: June 29, 2024
The
packaging
efficiency
is
the
key
for
food
safety
and
protection.
Petroleum-based
polymer
polyethylene,
are
frequently
utilized
in
despite
their
incredible
resistance
to
biodegradation.
In
view
of
growing
concerns
related
waste
accumulation
conventional
plastics
recycling
difficulty,
there
a
pressing
need
explore
further
sustainable
alternatives
produce
biodegradable
material.
Biopolymers
like
chitin
chitosan
from
Black
Soldier
Fly
(BSF)
could
be
suitable,
renewable
typical
synthetic
ones.
BSF
content
varies
8
%
24
%.
All
chitin-containing
fractions
can
collected
processed
chitosan.
Another
important
implication
chitosan,
due
antimicrobial
benefits,
production
coatings/films
effective
expanding
shelf
life
protection
packaged
food.
Introducing
bio-packaging
contributes
protect
environment
by
lowering
amount
plastic
pollution
addition
cost
reduction.
This
review
examines
extraction,
processing
potential
innovative
applications
industry.
Processing
methods:
physical,
chemical
biological
which
offer
variations
quality
purity
specific
were
presented.
enhancements
mechanical,
optical,
thermal
properties,
through
inclusion
chitin/
investigated
providing
plastics.
