Animal Husbandry and Fodder Production,
Journal Year:
2023,
Volume and Issue:
106(3), P. 121 - 137
Published: Jan. 1, 2023
Аннотация.Рост
и
морфобиохимические
значения
крови
являются
актуальными
показателями
здоровья
организма
рыб
при
изучении
влияния
кормовых
добавок
в
рационе.В
исследовании
рассмотрены
показатели
роста
параметры
карпа
(Cyprinus
carpio),
рацион
которого
дополнительно
вводили
для
I
опытной
группы
-ванилин
(250
мл/кг
корма),
II
-ферментные
препараты
Амилосубтилин
(0,5
г/кг
корма)
Глюкаваморин
III
-ультрадисперсные
частицы
SiO
2
(200
мг/кг
корма).Темп
прироста
живой
массы
показал
положительные
результаты,
начиная
с
пятой
недели
эксперимента.Было
установлено,
что
введение
сопровождается
повышением
на
7,31
%
(I
опытная),
5,41
(II
опытная)
7,62
(III
по
сравнению
контролем.Морфофизиологические
часть
биохимических
показателей
были
пределах
физиологической
нормы,
указало
отсутствие
негативного
годовиков
использовании
добавок.При
было
ванилин
способствовал
увеличению
общего
белка
44,62
(Р0,01),
альбумина
-на
63,71
АСТ
34,76
(Р0,001),
билирубина
132,92
холестерина
26,72
(Р0,05),
мочевины
27,27
(Р0,05)
креатинина
207,14
(Р0,001)
снижении
уровня
глюкозы
10,53
контрольными
значениями.Ферментные
привели
к
повышению
66,26
триглицеридов
64,17
271,43
(Р0,01)
42,11
22,42
40,91
относительно
контроля.Включение
УДЧ
SiO2
увеличило
уровень
90,53
36,36
71,43
контроля
41,11
АЛТ
56,49
29,17
контролем.Также
установлено
достоверное
повышение
железа
фосфора
во
всех
опытных
группах
магния
-в
группе
контрольных
значений.Так,
был
выше
72,11
70,0
107,37
138,16
86,18
55,26
I,
групп
соответственно.Уровень
контрольного
30,66
включении
ванилина.На
основании
результатов
исследования
сделан
вывод,
дополнительное
включение
может
быть
использовано
качестве
ростостимулирующих
компонентов
кормов
без
воздействия
рыб.
Animals,
Journal Year:
2023,
Volume and Issue:
13(16), P. 2625 - 2625
Published: Aug. 14, 2023
Hematological
analysis
is
commonly
used
to
assess
the
physiological
state
of
fish.
It
includes
red
blood
cell
parameters,
white
and
number
thrombocytes
per
volume
unit.
one
basic
tools
(often
accompanied
by
biochemical
histopathological
analyses)
influence
organic
inorganic
substances
on
is,
therefore,
applicable
in
both
ecotoxicology
pharmacotoxicology.
The
advantages
this
research
method
are
lack
need
for
specialized
laboratory
equipment
low
costs,
limitations
extensive
experience
among
personnel
performing
tests.
One
recommended
methods
supplementing
routinely
determined
hematological
parameters
assessing
cellular
composition
activity
hematopoietic
tissue.
As
there
very
little
scientific
data
available
issue
effects
xenobiotics
structure
fish
head
kidney
tissue,
filling
gap
should
be
considered
an
urgent
need.
Therefore,
we
recommend
conducting
with
simultaneous
use
as
reliable
complementary
impact
toxic
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(7), P. e28419 - e28419
Published: March 27, 2024
The
study
examined
the
potential
of
Silymarin,
a
blend
bioactive
flavonolignans
extracted
from
milk
thistle
Silybum
marianum,
to
mitigate
Deltamethrin-induced
toxicity
in
blood
Cyprinus
carpio.
Fish
were
exposed
Deltamethrin
(0.66
μg/L),
plant
extract,
or
combination
both
for
duration
thirty
days.
Various
parameters,
including
serum
biochemical
markers,
erythrocytic
abnormalities,
and
genotoxicity
endpoints,
assessed.
Results
indicated
significant
(p
<
0.05)
increase
levels
AST,
ALT,
ALP,
urea
nitrogen,
creatinine,
glucose,
cholesterol,
TLC
fish
pesticide.
Conversely,
total
protein,
TEC,
Hb
showed
notable
decrease.
There
was
also
rise
micronuclei
abnormalities
such
as
acanthocytes,
microcytes,
notched
cells.
Under
ultrastructural
examination,
phenotypic
deformities
like
spherocytosis,
discocytes,
clumped
erythrocytes
observed.
However,
dietary
supplementation
silymarin
(1
g/kg)
significantly
restored
biochemical,
genetic,
cellular
resembling
those
control
group.
This
suggests
this
extract
protecting
common
carp,
carpio,
damage
by
scavenging
free
radicals
reducing
DNA
oxidative
stress.
BMC Veterinary Research,
Journal Year:
2024,
Volume and Issue:
20(1)
Published: July 9, 2024
Abstract
Background
The
inappropriate
use
of
pesticides
including
fungicides
creates
severe
biological
hazards
that
can
endanger
fish
health
and
impede
sustainable
aquaculture.
Objective
This
study
investigated
the
negative
impacts
metiram
(MET),
a
fungicide
on
status
Nile
tilapia
(
Oreochromis
niloticus
)
for
96-hour
duration
as
an
acute
exposure
in
static
renewal
system.
Methods
Three
hundred
(average
body
weight:
37.50
±
0.22
g)
were
assigned
into
six
groups
(50
fish/group)
with
five
replicates
(10
fish/replicate).
Fish
exposed
to
various
concentrations
(0,
1.5,
3,
4.5,
6,
7.5
mg/L)
MET
water
without
exchange.
fish’s
behavior,
clinical
signs,
mortalities
documented
every
day
period.
Additionally,
MET’s
impact
blood
profile,
stress
biomarkers,
hepato-renal
functions,
immune-antioxidant
status,
brain
biomarker
closely
monitored.
Results
lethal
concentration
(LC
50
estimated
using
Finney’s
probit
technique
was
3.77
mg/L.
behavior
severely
impacted
by
exposure,
clear
increase
surfacing,
loss
equilibrium,
unusual
swimming,
laterality,
abnormal
movement,
decline
aggressive
behaviors.
survivability
hematological
indices
(white
red
cell
count,
differential
white
hematocrit
value,
hemoglobin)
significantly
reduced
concentration-dependent
manner
following
exposure.
Acute
(1.5–7.5
incrementally
increased
biomarkers
(nor-epinephrine,
cortisol,
glucose),
lipid
peroxides
(malondialdehyde),
oxidative
DNA
damage
(8-hydroxy-2-deoxyguanosine).
A
dysfunction
(4.5–7.5
evidenced
significant
alanine
aspartate
aminotransferases
creatinine
values.
Moreover,
substantial
immune
parameters
(lysozyme,
complement
serum
bactericidal
activity,
antiprotease
activity)
antioxidant
variables
(total
capacity,
superoxide
dismutase,
glutathione
peroxidase)
resulted
from
Conclusion
According
these
findings,
LC
triggered
toxicity
tilapia,
seen
alterations
neuro-behaviors,
functioning,
signifying
physiological
disturbances.
emphasizes
potential
ecological
dangers
provoked
environmental
contaminant
aquatic
systems.
However,
long-term
is
still
needed
be
investigated.
