Organic & Biomolecular Chemistry,
Journal Year:
2022,
Volume and Issue:
21(1), P. 127 - 131
Published: Dec. 6, 2022
In
this
article,
a
convenient
and
efficient
KIO3-promoted
oxidative
sulfenylation
at
the
β-position
of
tetrahydroisoquinolines
subsequent
aromatization
in
presence
elemental
S8
is
presented.
The
reaction
proceeds
with
moderate
to
good
yields
via
double
C-S
formation
process.
A
wide
range
structurally
diverse
4-sulfenylisoquinolines/3-sulfenylpiperidine
were
synthesized
excellent
functional
group
tolerance
high
efficiency.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(20), P. 3784 - 3789
Published: May 16, 2023
An
efficient
strategy
for
the
preparation
of
aryl
phosphonates
via
blue-light-promoted
single
electron
transfer
process
an
EDA
complex
between
phosphites
and
thianthrenium
salts
has
been
demonstrated.
The
corresponding
substituted
were
obtained
in
good
to
excellent
yields,
byproduct
thianthrene
can
be
recovered
reused
quantity.
This
developed
method
realizes
construction
through
indirect
C-H
functionalization
arenes,
which
potential
application
value
drug
discovery
development.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(17), P. 3541 - 3546
Published: April 24, 2024
Rapid
and
efficient
construction
of
multifunctionalized
skeletons
through
a
one-pot
multicompound
domino
reaction
has
been
recognized
as
simple
practical
strategy.
Herein,
visible-light-enabled
three-component
isothiocyanates,
isocyanides,
thianthrenium
salt-functionalized
arenes
is
presented,
which
affords
facile
approach
to
sulfur-containing
trisubstituted
imidazoles
in
good
yields
with
broad
substrate
scope
excellent
functional
group
tolerance.
The
byproduct
thianthrene
recovered
quantity,
thereby
ultimately
reducing
the
production
chemical
waste.
developed
methodology
potential
value
for
discovery
development
thioimidazole-based
drugs.
Chinese Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
42(12), P. 4037 - 4037
Published: Jan. 1, 2022
Sulfonium
salts
are
one
of
the
most
important
class
organosulfur
(IV)
compounds
which
have
a
positive
charge
on
sulfur
center
with
three
C-S
bonds.Because
their
bench-stable,
easy
synthesis,
broad
structural
diversity,
and
rich
reactivity,
sulfonium
playing
significant
role
in
synthetic
chemistry.In
recent
years,
visible-light
promoted
photoredox
catalysis
is
rapidly
developing
into
powerful
tool
for
organic
synthesis.In
this
paper,
advances
different
radical
type
reactions
induced
by
visible
light
summarized.The
formation
C-C
bond
C-X
(X＝B,
N,
O,
S,
Se,
Te,
F,
Cl,
I)
bonds
introduced,
applicable
scope
mechanism
some
also
discussed.Keywords
chemistry;
salt;
light;
free
reaction
有机硫化合物在合成化学、生物医学和功能有机材
料领域扮演着极其重要的角色
[1]
.据统计结果显示,
美
国销量排名前
200
位的药品中,
有
24.8%含有硫元素
[2]
.硫原子与同族的氧原子相比,
其半径更大、电负性更低,
使得硫的外电子层更易于接受或提供电子,
显示出独特
的反应活性,
而硫鎓盐是中心硫原子与三个取代基相连
的带正电的有机硫化合物(通式为[R
3
S]
＋
X
-).与同族氧
鎓盐相比,
硫鎓盐结构更加多样、热力学稳定性更强、
更易于合成、后处理更加简便
[3]
.常见的硫鎓盐的合成方法如
Scheme
1
所示
[4]
:
(a)通
过二卤代烃与硫醇的亲核取代反应,
该方法制备硫鎓盐
操作简便,
结晶度好且稳定性高,
但主要局限于五元环
和六元环状硫鎓盐的制备.(b)采用硫醚和烷基卤化物通
过分子间亲核取代反应制备硫鎓盐,
该方法是目前应用
有机化学
Green Chemistry,
Journal Year:
2022,
Volume and Issue:
25(2), P. 779 - 788
Published: Dec. 27, 2022
A
100%
atom-economical
iodosulfenylation
of
alkynes
is
developed
using
only
iodine
and
disulfides
via
the
in
situ
formation
corresponding
sulfenyl
iodide
intermediates
to
access
(
E
)-β-iodoalkenyl
sulfides
Z
)-tamoxifen.
Chinese Journal of Chemistry,
Journal Year:
2021,
Volume and Issue:
40(1), P. 97 - 103
Published: Oct. 5, 2021
Comprehensive
Summary
An
efficient
and
eco‐friendly
carbon
nitride
nanosheet
(NM‐g‐C
3
N
4
)‐catalyzed
decarboxylative
coupling
reaction
of
imidazo‐fused
heterocycles
(
i.e
.,
imidazo[1,2‐
a
]pyridines,
benzo[
d
]imidazo[2,1‐
b
]thiazole)
with
‐phenylglycines
in
dimethyl
carbonate
(DMC)
has
been
developed.
The
toxic
solvents,
external
oxidants,
restricted
conditions
could
be
effectively
avoided
this
powerful
sustainable
protocol.
Remarkably,
NM‐g‐C
straightforwardly
recovered
by
simple
centrifugation
recycled
reused
at
least
7
times
without
an
obvious
decrease
catalytic
activity.
Advanced Synthesis & Catalysis,
Journal Year:
2021,
Volume and Issue:
363(19), P. 4627 - 4631
Published: July 30, 2021
Abstract
This
paper
reports
the
transition
metal‐free
C(
sp
3
)−H
sulfenylation
of
arylacetamides
by
using
thiophenols
as
sulfenyl
reagents.
The
reactions
take
place
in
presence
only
K
PO
4
.
Control
experiments
indicate
that
proceed
via
a
featured
sulfur‐centred
free
radical
intermediate.
In
addition,
synthesis
2‐thiomethyl
benzoxazoles
has
been
realized
p
‐toluenesulfonic
acid
(
‐TSA)
promoted
annulation
sulfenylated
products.
magnified
image
