Synthesis of γ-keto sulfones through sulfonylation/acylation of alkenes merging NHC- and photo-catalysis DOI

Xu Sun,

Gan Zhang, Bo Ye

et al.

Molecular Catalysis, Journal Year: 2024, Volume and Issue: 569, P. 114563 - 114563

Published: Sept. 25, 2024

Language: Английский

Ferrocene/air double-mediated FeTiO3-photocatalyzed semi-heterogeneous annulation of quinoxalin-2(1H)-ones in EtOH/H2O DOI
Wen‐Tao Ouyang,

Hong‐Tao Ji,

Jun Jiang

et al.

Chemical Communications, Journal Year: 2023, Volume and Issue: 59(94), P. 14029 - 14032

Published: Jan. 1, 2023

With both ferrocene and air as the redox catalysts, for first time, low-cost natural ilmenite (FeTiO3) was successfully used photocatalytic bond formations. Under assistance of a traceless H-bond, HCHO methylene reagent, variety imidazo[1,5-a]quinoxalinones were semi-heterogeneously photosynthesized in high yields with good functional group compatibility.

Language: Английский

Citations

54
Oxamic acids: useful precursors of carbamoyl radicals DOI Creative Commons
Ikechukwu Martin Ogbu, Gülbin Kurtay, Frédéric Robert

et al.

Chemical Communications, Journal Year: 2022, Volume and Issue: 58(55), P. 7593 - 7607

Published: Jan. 1, 2022

Thermal, photochemical, or electrochemical-mediated decarboxylation of oxamic acids generate nucleophilic carbamoyl radicals, which react efficiently with unsaturated systems, but also amines, alcohols and thiols under oxidative conditions.

Language: Английский

Citations

45
Electrochemical radical annulation of 2-alkynyl biaryls with diselenides under catalyst- and chemical oxidant-free conditions DOI

Jun Jiang,

Keli Wang, Xiao Li

et al.

Chinese Chemical Letters, Journal Year: 2023, Volume and Issue: 34(12), P. 108699 - 108699

Published: June 17, 2023

Language: Английский

Citations

27
Visible light induced four component reaction of styrene for the access of thiodifluoroesters DOI

Shaohui Yang,

Jingcheng Song,

Hao Yang

et al.

Chinese Chemical Letters, Journal Year: 2023, Volume and Issue: 34(9), P. 108131 - 108131

Published: Jan. 5, 2023

Language: Английский

Citations

18
EDA Complex-Enabled Annulation to Access CF2-Containing Tetralones and Quinazolinones Using Persulfates as Electron Donors DOI
Shupeng Zhang, Dawei Guo,

Mei-Ling Yang

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(15), P. 10614 - 10623

Published: July 25, 2024

A photocatalyst-free and EDA complex-enabled radical cascade cyclization reaction of inactive alkenes with bromodifluoroacetamides was reported for the divergent synthesis fluorine-containing tetralones quinazolinones. In this transformation, persulfates as electron donors difluoro bromamide acceptors generate complex. This is a promising photochemical method advantages such mild conditions, simple operation, being metal-free, excellent functional group tolerance.

Language: Английский

Citations

7
Photoinduced carbamoylation reactions: unlocking new reactivities towards amide synthesis DOI
Bianca T. Matsuo, Pedro H. R. Oliveira, Emanuele F. Pissinati

et al.

Chemical Communications, Journal Year: 2022, Volume and Issue: 58(60), P. 8322 - 8339

Published: Jan. 1, 2022

In this review, we summarize the latest advances for amide moiety installation through photoinduced carbamoylation protocols.

Language: Английский

Citations

24
Transition metal-free photocatalytic radical annulation of 2-cyanoaryl acrylamides with difluoromethyl radicals to assemble 4-amino-quinolinone derivatives DOI

Wu Qiaoyan,

Niuniu Zhang,

Xirui Gong

et al.

Green Chemistry, Journal Year: 2023, Volume and Issue: 25(16), P. 6188 - 6193

Published: Jan. 1, 2023

A metal-free photocatalytic radical annulation of 2-cyanoaryl acrylamides with [CF 2 HPPh 3 ] + Br − to give 4-amino-quinolinones in good yields was developed. An easily obtained organophotocatalyst and green solvent acetone/H O were utilized the protocol.

Language: Английский

Citations

12
Recent advances in palladium-catalyzed reactions in water DOI

Dao‐Qing Dong,

Hao Yang,

Meng‐Yu Zhou

et al.

Current Opinion in Green and Sustainable Chemistry, Journal Year: 2023, Volume and Issue: 40, P. 100778 - 100778

Published: Feb. 6, 2023

Language: Английский

Citations

8
Cascade Cyclizations Triggered by Photochemically Generated Carbamoyl Radicals Derived from Alkyl Amines DOI

Ganesh Chandra Upreti,

Tavinder Singh,

Divakar Chaudhary

et al.

The Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 88(16), P. 11801 - 11808

Published: Aug. 9, 2023

We report on a visible light-mediated cascade carbamoylation/cyclization of acrylamides using dihydropyridyl carbamoyl donors derived from alkyl amines. Diversely selected including 2-cyano-N-arylacrylamides, indolyl- and benzimidazolyl acrylamides, 2-alkynyl-N-aryl participate in this reaction, providing products good yields. The highlights photochemical method include the application amine-derived donors, peroxide-free reaction conditions, broad scope.

Language: Английский

Citations

6
Persulfate-Promoted Carbamoylation/Cyclization of Alkenes: Synthesis of Amide-Containing Quinazolinones DOI Creative Commons
Jia-Jun Tang, Mengyang Zhao,

Ying-Jun Lin

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(5), P. 997 - 997

Published: Feb. 25, 2024

The incorporation of amide groups into biologically active molecules has been proven to be an efficient strategy for drug design and discovery. In this study, we present a simple practical method the synthesis amide-containing quinazolin-4(3H)-ones under transition-metal-free conditions. This is achieved through carbamoyl-radical-triggered cascade cyclization N3-alkenyl-tethered quinazolinones. Notably, carbamoyl radical generated in situ from oxidative decarboxylative process oxamic acids presence (NH4)2S2O8.

Language: Английский

Citations

2