Chemistry - An Asian Journal,
Journal Year:
2024,
Volume and Issue:
19(12)
Published: April 17, 2024
Abstract
Chemosensing,
an
interdisciplinary
scientific
domain,
plays
a
pivotal
role
ranging
from
environmental
monitoring
to
healthcare
diagnostics
and
(inter)national
security.
Metal‐organic
gels
(MOGs)
are
recognized
for
their
stability,
selectivity,
responsiveness,
making
them
valuable
chemosensing
applications.
Researchers
have
explored
the
development
of
MOGs
based
on
different
metal
ions
ligands,
allowing
tailored
properties
sensitivities,
even
demonstrated
applications
as
portable
sensors
such
paper‐based
test
strips
practical
use.
Herein,
several
studies
related
in
field
via
UV‐visible
or
luminance
along
with
electrochemical
approach
presented.
These
papers
versatile
materials
use
sensing
bio
analytes.
This
review
provides
foundational
understanding
key
concepts,
methodologies,
recent
advancements
this
field,
fostering
community.
Chemical Reviews,
Journal Year:
2024,
Volume and Issue:
124(20), P. 11242 - 11347
Published: Oct. 9, 2024
Biopsy,
including
tissue
and
liquid
biopsy,
offers
comprehensive
real-time
physiological
pathological
information
for
disease
detection,
diagnosis,
monitoring.
Fluorescent
probes
are
frequently
selected
to
obtain
adequate
on
processes
in
a
rapid
minimally
invasive
manner
based
their
advantages
biopsy.
However,
conventional
fluorescent
have
been
found
show
aggregation-caused
quenching
(ACQ)
properties,
impeding
greater
progresses
this
area.
Since
the
discovery
of
aggregation-induced
emission
luminogen
(AIEgen)
promoted
advancements
molecular
bionanomaterials
owing
unique
high
quantum
yield
(QY)
signal-to-noise
ratio
(SNR),
ACS Sensors,
Journal Year:
2024,
Volume and Issue:
9(6), P. 2705 - 2727
Published: June 6, 2024
The
ultrasensitive
recognition
of
biomarkers
plays
a
crucial
role
in
the
precise
diagnosis
diseases.
Graphene-based
field-effect
transistors
(GFET)
are
considered
most
promising
devices
among
next
generation
biosensors.
GFET
biosensors
possess
distinct
advantages,
including
label-free,
ease
integration
and
operation,
ability
to
directly
detect
liquid
environments.
This
review
summarized
recent
advances
for
biomarker
detection,
with
focus
on
interface
functionalization.
Various
sensitivity-enhancing
strategies
have
been
overviewed
biosensors,
from
perspective
optimizing
graphene
synthesis
transfer
methods,
refinement
surface
functionalization
channel
layer
gate
electrode,
design
biorecognition
elements
reduction
nonspecific
adsorption.
Further,
this
extensively
explores
functionalized
antibodies,
aptamers,
enzymes.
It
delves
into
employed
detection
various
diseases
(such
as
cancer,
cardiovascular
diseases,
neurodegenerative
disorders,
infectious
viruses,
etc.)
along
their
application
integrated
microfluidic
systems.
Finally,
issues
challenges
modulation
biosensing
interfaces
faced
by
detecting
biomarkers.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(27), P. 34538 - 34548
Published: June 28, 2024
Biothiol
assays
offer
vital
insights
into
health
assessment
and
facilitate
the
early
detection
of
potential
issues,
thereby
enabling
timely
effective
interventions.
In
this
study,
we
developed
ultrasmall
CuMn-Histidine
(His)
nanozymes
with
multiple
enzymatic
activities.
CuMn-His
enhanced
peroxidase
(POD)-like
activity
at
neutral
pH
was
achieved
through
hydrogen
bonding
electrostatic
effects.
addition,
possesses
laccase
(LAC)-like
superoxide
dismutase
(SOD)-like
activities
pH.
Based
on
three
different
enzyme
mimetic
pH,
colorimetric
sensing
array
without
changing
buffer
solution
successfully
constructed.
The
used
for
identification
biothiols,
glutathione
(GSH),
cysteine
(Cys),
homocysteine
(Hcy).
Subsequently,
excellent
application
results
were
shown
in
complex
serum
cellular
level
analyses.
This
study
provides
an
innovative
strategy
development
bimetallic
construction
arrays.
Small,
Journal Year:
2024,
Volume and Issue:
20(33)
Published: March 26, 2024
Multidimensional
metabolic
analysis
has
become
a
new
trend
in
establishing
efficient
disease
monitoring
systems,
as
the
constraints
associated
with
relying
solely
on
single
dimension
refined
are
increasingly
pronounced.
Here,
coordination
polymers
employed
derivative
precursors
to
create
multishell
hollow
hybrids,
developing
an
integrated
system.
Briefly,
fingerprints
extracted
from
hundreds
of
serum
samples
and
urine
samples,
encompassing
not
only
membranous
nephropathy
but
also
related
diseases,
using
high-throughput
mass
spectrometry.
With
optimized
algorithm
initial
feature
selection,
established
combined
panel
demonstrates
enhanced
accuracy
both
subtype
differentiation
(over
98.1%)
prognostic
95.6%),
even
during
double
blind
test.
This
surpasses
biomarker
(≈90.7%
for
subtyping,
≈89.7%
prognosis)
(≈94.4%
≈76.5%
prognosis).
Moreover,
after
attempting
further
refine
marker
panel,
test
maintains
equal
sensitivity,
specificity,
accuracy,
showcasing
comprehensive
improvement
over
single-fluid
approach.
underscores
remarkable
effectiveness
superiority
strategy
discriminating
between
MN
other
groups.
work
potential
significantly
advance
diagnostic
medicine,
leading
establishment
more
effective
strategies
patient
management.
