Colloids and Surfaces B Biointerfaces, Journal Year: 2023, Volume and Issue: 222, P. 113129 - 113129
Published: Jan. 4, 2023
Language: Английский
Colloids and Surfaces B Biointerfaces, Journal Year: 2023, Volume and Issue: 222, P. 113129 - 113129
Published: Jan. 4, 2023
Language: Английский
Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 84, P. 104537 - 104537
Published: May 11, 2023
Language: Английский
Citations
26International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 251, P. 126276 - 126276
Published: Aug. 13, 2023
Language: Английский
Citations
26European Polymer Journal, Journal Year: 2024, Volume and Issue: 209, P. 112906 - 112906
Published: March 6, 2024
Language: Английский
Citations
14Advanced NanoBiomed Research, Journal Year: 2024, Volume and Issue: 4(3)
Published: Jan. 8, 2024
Significant challenges persist in enhancing the delivery efficiency of tumor nanomedicines, predominantly due to difficulty successfully surpassing pathophysiological barriers. Enhancing penetration nanomedicines such conditions represents a pivotal goal advancing anticancer nanotherapeutics. Transcytosis emerges as promising solution this context, addressing limitations passive drug delivery. By harnessing diverse stimuli induce transcytosis, nanocarriers can achieve precise and deep penetration, resulting high therapeutic efficacy reduced systemic exposure compound. This review briefly examines various stimuli‐responsive nanosystems offers an overview outlook on development for transcytosis‐based cancer delivery, aiming provide informative insights design capable tissue enhanced efficacy.
Language: Английский
Citations
12Advanced Materials, Journal Year: 2024, Volume and Issue: 36(23)
Published: Feb. 20, 2024
Abstract In recent years, tremendous effort is devoted to developing platforms, such as implantable drug delivery systems (IDDSs), with temporally and spatially controlled release capabilities improved adherence. IDDSs have multiple advantages: i) the timing location of can be by patients using specific stimuli (light, sound, electricity, magnetism, etc.). Some intelligent “closed‐loop” IDDS even realize self‐management without human participation. ii) enable continuous stable drugs over a long period (months years) iii) administer directly lesion, thereby helping reduce dosage side effects. iv) personalized according patient needs. The high demand for has prompted scientists make efforts develop IDDS. this review, several common stimulus‐responsive mechanisms including endogenous (e.g., pH, reactive oxygen species, proteins, etc.) exogenous light, etc.), are given in detail. Besides, types reported years reviewed, various based on above mechanisms, radio frequency‐controlled IDDS, self‐powered etc. Finally, advantages disadvantages bottleneck problems, possible solutions analyzed provide directions subsequent research.
Language: Английский
Citations
10Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 99, P. 102393 - 102393
Published: June 24, 2024
Language: Английский
Citations
10Nano Energy, Journal Year: 2024, Volume and Issue: 127, P. 109732 - 109732
Published: May 15, 2024
Language: Английский
Citations
9The International Journal of Advanced Manufacturing Technology, Journal Year: 2025, Volume and Issue: 136(10), P. 4215 - 4237
Published: Feb. 1, 2025
Language: Английский
Citations
1Advanced Composites and Hybrid Materials, Journal Year: 2022, Volume and Issue: 6(1)
Published: Dec. 19, 2022
Language: Английский
Citations
36Polymers, Journal Year: 2022, Volume and Issue: 14(23), P. 5249 - 5249
Published: Dec. 1, 2022
Doxorubicin (DOX) is one of the most commonly used drugs in liver cancer. Unfortunately, traditional chemotherapy with DOX presents many limitations, such as a systematic release DOX, affecting both tumor tissue and healthy tissue, leading to apparition side effects, multidrug resistance (MDR), poor water solubility. Furthermore, drug delivery systems’ responsiveness has been intensively studied according influence different internal external stimuli on efficiency therapeutic drugs. In this review, we discuss stimuli-responsive drug-delivery systems, redox, pH temperature variation, application magnetic, photo-thermal, electrical stimuli, for controlled cancer therapy, along future perspectives these smart systems therapy.
Language: Английский
Citations
34