Trends in the Incorporation of Antiseptics into Natural Polymer-Based Nanofibrous Mats DOI Open Access
Lenka Piskláková, Kristýna Skuhrovcová,

Tereza Bártová

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(5), P. 664 - 664

Published: Feb. 29, 2024

Nanofibrous materials represent a very promising form of advanced carrier systems that can be used industrially, especially in regenerative medicine as highly functional bandages, or wound dressings. By incorporation antimicrobial additives directly into the structure nanofiber carrier, functionality layer is upgraded, depending on final requirement-bactericidal, bacteriostatic, antiseptic, generally effect. Such nanofibrous layers prepared mostly by electrospinning technology from both synthetic and natural polymers. The presence polymer composition advantageous. Especially medical applications where, due to material close human body, healing process more efficient without occurrence an unwanted inflammatory response. However, converting polymers form, with homogeneously distributed stable additive, great challenge. Thus, combination often used. This review clearly summarizes issue effectiveness different types substances, such nanoparticles, antibiotics, common antiseptics, substances origin, electrospun made materials. A section describing problematic aspects also included.

Language: Английский

Insights into Materials, Physics, and Applications in Flexible and Wearable Acoustic Sensing Technology DOI

Zhiwei Lin,

Shengshun Duan, Mingyang Liu

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 36(9)

Published: Nov. 28, 2023

Sound plays a crucial role in the perception of world. It allows to communicate, learn, and detect potential dangers, diagnose diseases, much more. However, traditional acoustic sensors are limited their form factors, being rigid cumbersome, which restricts applications. Recently, have made significant advancements, transitioning from rudimentary forms wearable devices smart everyday clothing that can conform soft, curved, deformable surfaces or surroundings. In this review, latest scientific technological breakthroughs with insightful analysis materials, physics, design principles, fabrication strategies, functions, applications flexible sensing technology comprehensively explored. The new generation recognize voice, interact machines, control robots, enable marine positioning localization, monitor structural health, human vital signs deep tissues, perform organ imaging is highlighted. These innovations offer unique solutions challenges fields such as healthcare, biomedicine, wearables, robotics, metaverse. Finally, existing future opportunities field addressed, providing strategies advance technologies for intriguing real-world inspire research directions.

Language: Английский

Citations

44

Metal-organic framework-based dressings: Application and opportunities in wound healing DOI

Qianying Huang,

Ying Chen,

Min Ye

et al.

Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 40, P. 102235 - 102235

Published: Aug. 20, 2024

Language: Английский

Citations

42

MOFs and MOF‐Based Composites as Next‐Generation Materials for Wound Healing and Dressings DOI Creative Commons
Ashkan Bigham,

Negar Islami,

Arezoo Khosravi

et al.

Small, Journal Year: 2024, Volume and Issue: 20(30)

Published: March 7, 2024

Abstract In recent years, there has been growing interest in developing innovative materials and therapeutic strategies to enhance wound healing outcomes, especially for chronic wounds antimicrobial resistance. Metal–organic frameworks (MOFs) represent a promising class of next‐generation dressings. Their high surface area, pore structures, stimuli‐responsiveness, antibacterial properties, biocompatibility, potential combination therapies make them suitable complex care challenges. MOF‐based composites promote cell proliferation, angiogenesis, matrix synthesis, acting as carriers bioactive molecules promoting tissue regeneration. They also have stimuli‐responsivity, enabling photothermal skin cancer infections. Herein, critical analysis the current state research on MOFs dressings is provided, offering valuable insights into applications, challenges, future directions this field. This literature review targeted multifunctionality nature wound‐disease therapy from different aspects discussed most advancements made context, reader will find how contributed field yield more effective, functional, they lead next generation biomaterials

Language: Английский

Citations

36

Biomedical Metal–Organic framework materials on antimicrobial therapy: Perspectives and challenges DOI
Wenbin Hu, Qin Ouyang, Chenyi Jiang

et al.

Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 41, P. 102300 - 102300

Published: Sept. 7, 2024

Language: Английский

Citations

26

Smart Nano-Hybrid Metal-Organic Frameworks: Revolutionizing Advancements, Applications, and Challenges in Biomedical Therapeutics and Diagnostics DOI Creative Commons
Dilip Kumar Chandra, Awanish Kumar, Chinmaya Mahapatra

et al.

Hybrid Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100406 - 100406

Published: Feb. 1, 2025

Language: Английский

Citations

2

One-Pot Synthesis of Degradable and Renewable Cellulose-Based Packaging Films DOI
Yuancheng Zhang,

Fengqiong Jiang,

Wenxin Zhao

et al.

ACS Sustainable Chemistry & Engineering, Journal Year: 2022, Volume and Issue: 10(50), P. 16871 - 16881

Published: Dec. 5, 2022

Among all of the plastic pollutants, cling packaging films pose a particularly complex problem due to their high consumption, poor reusability, difficulty in recycling, and nondegradability. Despite many efforts by researchers develop alternatives films, none have been satisfactory. Here, cellulose-based active that are degradable, renewable, reusable were prepared one-pot green synthesis silver-based metal–organic frameworks on carboxymethyl cellulose (Ag-2MI@CMC). The preparation process is simple (water solvent system with normal temperature pressure). Ag-2MI@CMC composite film exhibits better performance than commercial PE including (1) mechanical properties antifog performance, has tensile strength about 61 MPa, while only 35 (2) excellent antimicrobial properties, bacteria mold, did not exhibit any antibacterial (3) fruit preservation (4) natural degradability (complete degradation takes 45 days, during which time does degrade at all), (5) renewable more five times, recycled still maintains good effect. Given low raw material cost superior film, may be suitable solution solve environmental challenges brought volume films.

Language: Английский

Citations

40

Antibacterial and antioxidant wound dressings with pH responsive release properties accelerate chronic wound healing DOI

Wuxiu Cao,

Dan Xia, Linxi Zhou

et al.

Materials Today Physics, Journal Year: 2023, Volume and Issue: 40, P. 101316 - 101316

Published: Dec. 15, 2023

Language: Английский

Citations

31

Multifunctional metal–organic frameworks for wound healing and skin regeneration DOI Creative Commons
Fei Xing, Hong Ma, Peiyun Yu

et al.

Materials & Design, Journal Year: 2023, Volume and Issue: 233, P. 112252 - 112252

Published: Aug. 18, 2023

Various wounds caused by burns, trauma, surgery, and genetic irregularities, including acute chronic wounds, pose a huge burden on global healthcare. Many therapeutic strategies, such as nanomedicine regenerative medicine, have been applied to wound repair skin regeneration. As promising exciting nanomaterial, metal-organic frameworks (MOFs) encompass many desirable properties, crystalline porous structure, tunable size, good mechanical stability, large specific surface area, exceptional chemical stability. Most importantly, the performance of MOFs can be modulated changing synthesis steps conditions. release metal ions modulate cellular behaviors kill various microorganisms, which meets this dual agent strategy for healing Additionally, act carriers delivering bioactive agents in desired manner. Recently, an increasing number researchers conducted studies applying Based this, we perform study report current status further perspective MOFs-based strategy. Furthermore, molecular process fabrication were also discussed.

Language: Английский

Citations

28

Advanced Metallized Nanofibers for Biomedical Applications DOI Creative Commons
Wei Sang, Ruiping Zhang, Xiangyang Shi

et al.

Advanced Science, Journal Year: 2023, Volume and Issue: 10(27)

Published: Aug. 2, 2023

Nanofibers are long, wire-like materials with nanoscale diameters and specific length diameter ratios. have porous reticular networks remarkably high surface areas significant interconnectivity between pores, allowing for the chemical modification loading of drugs. Metallized nanofibers novel that enhance performance attributes conventional by combining metals through electrostatic spinning doping, modification, approaches. Due to their unique physical properties, metallized diverse, rapidly developed in fields chemistry, science, battery preparation. To date, improvement advanced preparation techniques biocompatibility levels materials, nanofiber applications gradually expanding into biomedical field due excellent thermal electrical conductivities metal properties. In this review, biomedicine summarized. It is suggested prepare multifunctional tissue engineering, drug delivery, tumor treatment, wound healing, biosensing taking safety stability as main material selection guidelines. Finally, development summarized discussed.

Language: Английский

Citations

23

Intelligent Electrospinning Nanofibrous Membranes for Monitoring and Promotion of Wound Healing DOI Creative Commons
Zhi Qu, Yang Wang, Yanhong Dong

et al.

Materials Today Bio, Journal Year: 2024, Volume and Issue: 26, P. 101093 - 101093

Published: May 18, 2024

The incidence of chronic wound healing is promoted by the growing trend elderly population, obesity, and type II diabetes. Although numerous dressings have been studied over years, it still challenging for many to perfectly adapt process due dynamic complicated microenvironment. Aiming at an optimal reproduction physiological environment, multifunctional electrospinning nanofibrous membranes (ENMs) emerged as a promising platform treatment owing their resemblance extracellular matrix (ECM), adjustable preparation processes, porousness, good conformability site. Moreover, profiting from booming development human-machine interaction artificial intelligence, next generation intelligent (iENMs) based dressing substrates that could realize real-time monitoring proceeding individual-based therapy has evoked surge interest. In this regard, general wound-related biomarkers are overviewed firstly representative iENMs stimuli-responsive materials briefly summarized. Subsequently, emergent applications highlighted. Finally, opportunities challenges next-generation well translating into clinical practice evaluated.

Language: Английский

Citations

16