Recent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior

Progress in Neurobiology, Journal Year: 2019, Volume and Issue: 179, P. 101607 - 101607

Published: March 22, 2019

Language: Английский

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An Engineered orco Mutation Produces Aberrant Social Behavior and Defective Neural Development in Ants

Cell, Journal Year: 2017, Volume and Issue: 170(4), P. 736 - 747.e9

Published: Aug. 1, 2017

Language: Английский

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Fat Body—Multifunctional Insect Tissue

Insects, Journal Year: 2021, Volume and Issue: 12(6), P. 547 - 547

Published: June 11, 2021

The biodiversity of useful organisms, e.g., insects, decreases due to many environmental factors and increasing anthropopressure. Multifunctional tissues, such as the fat body, are key elements in proper functioning invertebrate organisms resistance factors. body is center metabolism, integrating signals, controlling molting metamorphosis, synthesizing hormones that control whole synthesis immune system proteins. In cells, lipids, carbohydrates proteins substrates products pathways can be used for energy production, accumulate reserves, mobilize at appropriate stage life (diapause, flight), determining survival an individual. main tissue responsible innate acquired humoral immunity. produces bactericidal polypeptides, i.e., lysozyme. also important early stages insect’s production vitellogenin, yolk protein needed development oocytes. Although a lot information available on its structure biochemistry, interesting research topic which much still discovered.

Language: Английский

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Social regulation of insulin signaling and the evolution of eusociality in ants

Science, Journal Year: 2018, Volume and Issue: 361(6400), P. 398 - 402

Published: July 26, 2018

Queens and workers of eusocial Hymenoptera are considered homologous to the reproductive brood care phases an ancestral subsocial life cycle. However, molecular mechanisms underlying evolution division labor remain obscure. Using a brain transcriptomics screen, we identified single gene,

Language: Английский

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The Role of Peptide Hormones in Insect Lipid Metabolism

Frontiers in Physiology, Journal Year: 2020, Volume and Issue: 11

Published: May 7, 2020

Lipids are the primary storage molecules and an essential source of energy in insects during reproduction, prolonged periods flight, starvation, diapause. The coordination center for insect lipid metabolism is fat body, which analogous to vertebrate adipose tissue liver. body primarily composed adipocytes, accumulate triacylglycerols intracellular droplets. Genomics proteomics, together with functional analyses, such as RNA interference CRISPR/Cas9-targeted genome editing, identified various genes involved elucidated their functions. However, endocrine control metabolism, particular roles peptide hormones lipogenesis lipolysis relatively less-known topics. In current review, neuropeptides that directly or indirectly affect introduced. lipolytic lipogenic adipokinetic hormone brain insulin-like peptides (ILP2, ILP3, ILP5). Other neuropeptides, insulin-growth factor ILP6, neuropeptide F, allatostatin-A, corazonin, leucokinin, tachykinins limostatin, might stimulate lipolysis, while diapause hormone-pheromone biosynthesis activating neuropeptide, short CCHamide-2, cytokines Unpaired 1 2 induce lipogenesis. Most these interact one another, but mostly insulin signaling, therefore indirectly. Peptide also diapause, infections immunity; highlighted. review concludes a discussion potential metabolism-related pest management.

Language: Английский

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The Mechanisms of Social Immunity Against Fungal Infections in Eusocial Insects

Toxins, Journal Year: 2019, Volume and Issue: 11(5), P. 244 - 244

Published: April 29, 2019

Entomopathogenic fungus as well their toxins is a natural threat surrounding social insect colonies. To defend against them, insects have evolved series of unique disease defenses at the colony level, which consists behavioral and physiological adaptations. These colony-level can reduce infection poisoning risk improve survival societal members, known immunity. In this review, we discuss how immunity enables to avoid, resist tolerate fungal pathogens. understand molecular basis immunity, highlight several genetic elements biochemical factors that drive defense, needs further verification. We chemosensory genes in regulating behaviors, antifungal secretions such some venoms external defense immune priming internal defense. conclude, show possible driving force for evolution Throughout propose questions involved extended from phenomena been reported. hope our review about 'host-fungal pathogen' interactions will help us mechanism eusocial insects.

Language: Английский

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Convergent eusocial evolution is based on a shared reproductive groundplan plus lineage-specific plastic genes

Nature Communications, Journal Year: 2019, Volume and Issue: 10(1)

Published: June 14, 2019

Abstract Eusociality has convergently evolved multiple times, but the genomic basis of caste-based division labor and degree to which independent origins eusociality have utilized common genes remain largely unknown. Here we characterize caste-specific transcriptomic profiles across development adult body segments from pharaoh ants ( Monomorium pharaonis ) honey bees Apis mellifera ), representing two eusociality. We identify a substantial shared core upregulated in abdomens queen that also tends be mated female flies, suggesting these are part conserved insect reproductive groundplan. Outside this groundplan, few differentially expressed common. Instead, majority thousands caste-associated plastically expressed, rapidly evolving, relatively evolutionarily young. These results emphasize recruitment both highly lineage-specific underlie convergent evolution novel traits such as

Language: Английский

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Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones

Cell, Journal Year: 2021, Volume and Issue: 184(23), P. 5807 - 5823.e14

Published: Nov. 1, 2021

Language: Английский

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Insulin signaling in the long-lived reproductive caste of ants

Science, Journal Year: 2022, Volume and Issue: 377(6610), P. 1092 - 1099

Published: Sept. 1, 2022

In most organisms, reproduction is correlated with shorter life span. However, the reproductive queen in eusocial insects exhibits a much longer span than that of workers.

Language: Английский

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Exploring the genetics of social behaviour in C. calcarata

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 15, 2025

Studies investigating social evolution often focus on species that are obligately eusocial, where presumably all of the adaptive genetic changes associated with sociality have already been completed. To fully understand eusociality, we must study facultative behaviour. The small carpenter bee Ceratina calcarata is an ideal model for studying genetics and molecular biology eusocial as it can exhibit both subsocial behaviour parental care facilitated by altruistic dwarf eldest daughter. Here, sequenced genomes C. to identify mutations genes used these data test several hypotheses related eusociality. Many single nucleotide polymorphisms had high levels differentiation (Fst) between were in or near regions important regulating gene expression. These results consistent Genetic Toolkit Hypothesis evolution. Our findings suggest low behavioural complexity observed may involve modulation existing regulatory networks generate phenotypes

Language: Английский

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