Microbiome transfer from native to invasive species may increase invasion risk DOI Creative Commons
Maria M. Martignoni, Oren Kolodny

Proceedings of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 291(2034)

Published: Nov. 1, 2024

In a fast-changing world, understanding how organisms adapt to their environment is pressing necessity. Research has focused on genetic adaptation, while our of non-genetic modes still in its infancy. The host-associated microbiome can be considered mode which strongly influence an organism’s ability cope with environment. However, the role host ecological dynamics largely unexplored, particularly animal communities. Here, we discuss following hypothesis: invasive species may rapidly local conditions by adopting beneficial microbes from similar co-occurring native species. This occurs when invader’s fitness influenced adaptation that facilitated acquired microbiomes. We present minimal mathematical model explore this hypothesis and show delayed acquisition explain occurrence invasion lag. Overall, results contribute broadening conceptualization rapid via transfer offer insights towards designing early intervention strategies for management.

Language: Английский

Host control of the microbiome: Mechanisms, evolution, and disease DOI Creative Commons
Jacob Wilde, Emma Slack, Kevin R. Foster

et al.

Science, Journal Year: 2024, Volume and Issue: 385(6706)

Published: July 18, 2024

Many species, including humans, host communities of symbiotic microbes. There is a vast literature on the ways these microbiomes affect hosts, but here we argue for an increased focus how hosts their microbiomes. Hosts exert control over symbionts through diverse mechanisms, immunity, barrier function, physiological homeostasis, and transit. These mechanisms enable to shape ecology evolution generate natural selection microbial traits that benefit host. Our result from perpetual tension between symbiont evolution, can leverage host's evolved abilities regulate microbiota prevent treat disease. The study will be central our ability both understand manipulate microbiotas better health.

Language: Английский

Citations

25
A systematic framework for understanding the microbiome in human health and disease: from basic principles to clinical translation DOI Creative Commons

Ziqi Ma,

Tao Zuo, Norbert Frey

et al.

Signal Transduction and Targeted Therapy, Journal Year: 2024, Volume and Issue: 9(1)

Published: Sept. 23, 2024

Language: Английский

Citations

20
The microbiota: a crucial mediator in gut homeostasis and colonization resistance DOI Creative Commons
Yiding Chen, Ling Xiao, Min Zhou

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 6, 2024

The gut microbiota is a complex and diverse community of microorganisms that colonizes the human gastrointestinal tract influences various aspects health. These microbes are closely related to enteric infections. As foreign entity for host, commensal restricted regulated by barrier immune system in contributes homeostasis. Commensals also effectively resist colonization pathogens overgrowth indigenous pathobionts utilizing variety mechanisms, while have developed strategies subvert resistance. Dysbiosis microbial can lead acts as pivotal mediator establishing harmonious mutualistic symbiosis with host shielding against pathogens. This review aims provide comprehensive overview mechanisms underlying host-microbiome microbiome-pathogen interactions, highlighting multi-faceted roles preventing We discuss applications manipulating treat infectious diseases gut.

Language: Английский

Citations

11
The gut microbiome in disorders of gut–brain interaction DOI Creative Commons
Narjis Kraïmi,

Taylor Ross,

Julien Pujo

et al.

Gut Microbes, Journal Year: 2024, Volume and Issue: 16(1)

Published: July 1, 2024

Functional gastrointestinal disorders (FGIDs), chronic characterized by either abdominal pain, altered intestinal motility, or their combination, have a worldwide prevalence of more than 40% and impose high socioeconomic burden with significant decline in quality life. Recently, FGIDs been reclassified as gut-brain interaction (DGBI), reflecting the key role bidirectional communication these impact on psychological comorbidities. Although, during past decades, field DGBIs has advanced significantly, molecular mechanisms underlying pathogenesis pathophysiology, gut microbiome processes are not fully understood. This review aims to discuss latest body literature complex microbiota-gut-brain interactions implications DGBIs. A better understanding existing pathways between brain holds promise developing effective therapeutic interventions for

Language: Английский

Citations

10
Effect of Relocation, Social Housing Changes, and Diarrhea Status on Microbiome Composition of Juvenile Cynomolgus Macaques (Macaca fascicularis) DOI Creative Commons
Keely McGrew,

Nicole Monts de,

Therese A. Kosten

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(1), P. 98 - 98

Published: Jan. 7, 2025

Social housing changes are likely stressful and can be associated with diarrhea, the most common health problem noted in captive macaque populations. Diarrhea may reflect a negative shift gut flora ("gut dysbiosis"). This study reported on microbiome composition of juvenile primates (Macaca fascicularis) that experienced change social exhibited diarrhea. A matched-case-control design was utilized to compare fecal samples from gut-unhealthy animals healthy counterparts (n = 61). Baseline recently imported were collected during routine sedation events. When an animal change, entire cohort monitored for Post-relocation diarrhea their matched controls. Samples assessed via 16S rRNA next-generation sequencing analysis by ELISA cortisol levels. Fecal levels did not differ between groups or across time points. Alpha diversity increased after relocation differed sex males demonstrating greater alpha (p < 0.01). Although exhibiting affect levels, it beta 0.05). Understanding how affected will help guide prevention strategies such as use specific probiotics reduce incidence

Language: Английский

Citations

1
Analysis of the Efficacy of MALDI-TOF MS Technology in Identifying Microorganisms in Cancer Patients and Oncology Hospital Environment DOI Creative Commons

Grażyna Czeszewska-Rosiak,

Iwona Adamczyk, Agnieszka Ludwiczak

et al.

Heliyon, Journal Year: 2025, Volume and Issue: 11(2), P. e42015 - e42015

Published: Jan. 1, 2025

Rapid diagnostics of microbes in hospitals are crucial for promptly identifying infections, enabling timely and appropriate treatment. The study was conducted to evaluate the effectiveness matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI TOF MS) technology microbial profiling hospital environments patient samples. objective determine landscape swabs collected from hospitalized patients their immediate environments, using MALDI compare capabilities two systems: BRUKER ZYBIO. analysis resulted 1012 identifications samples (N = 81), encompassing 96 species, 1496 surface 108), covering 124 species. Predominantly identified microorganisms patients' included Staphylococcus epidermidis, aureus, capitis, Steptococcus salivarius, Micrococcus luteus, whereas environmental chiefly yielded S. hominis, warneri, Microcccus luteus. 33 species were found both types samples, highlighting a significant interchange within settings. Both systems showed high consistency results at genus levels. Nevertheless, mismatches identification between noted, particularly Brevibacterium, Streptococcus, Bacillus, Staphylococcus, Neisseria genera. This presents precision highlights need ongoing enhancements, especially expansion updating databases, bolster its diagnostic further.

Language: Английский

Citations

1
Probiotics and gut microbiota modulation: implications for skin health and disease management DOI

Elahe Parhizkar,

Parisa Vosough,

Maryam Baneshi

et al.

Archives of Microbiology, Journal Year: 2025, Volume and Issue: 207(3)

Published: Feb. 23, 2025

Language: Английский

Citations

1
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure DOI Creative Commons
Jacobo de la Cuesta‐Zuluaga, Leonardo Boldt, Lisa Maier

et al.

Cell Host & Microbe, Journal Year: 2024, Volume and Issue: 32(6), P. 786 - 793

Published: June 1, 2024

Survival strategies of human-associated microbes to drug exposure have been mainly studied in the context bona fide pathogens exposed antibiotics. Less well understood are survival non-pathogenic and host-associated commensal communities variety drugs xenobiotics which humans exposed. The lifestyle microbial commensals within complex offers a ways adapt different drug-induced stresses. Here, we review responses employed by gut when drugs-antibiotics non-antibiotics-at individual community level. We also discuss factors influencing recovery establishment new structure following exposure. These key stability resilience microbiome, ultimately overall health well-being host.

Language: Английский

Citations

7
Linking microbiome temporal dynamics to host ecology in the wild DOI Creative Commons
Kirsty J. Marsh,

Stuart Bearhop,

Xavier A. Harrison

et al.

Trends in Microbiology, Journal Year: 2024, Volume and Issue: 32(11), P. 1060 - 1071

Published: May 25, 2024

Ignoring the dynamic nature of microbial communities risks underestimating power microbes to impact health their hosts. Microbiomes are thought be important for host fitness, yet coarse temporal scale and population-level focus many studies precludes ability investigate importance among-individual variation in stability identify ecological contexts which this matters. Here we briefly summarise current knowledge dynamics wild host-associated communities. We then discuss implications microbiota suggest analytical approaches understanding these patterns. One major requirement is future conduct individual-level longitudinal analyses, with some systems already well set up answering questions.

Language: Английский

Citations

5
Advancements in the impact of human microbiota and probiotics on leukemia DOI Creative Commons
Yi Zhang, Xiaotong Zhao, Jingxian Zhang

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: July 3, 2024

The human gut microbiota is a complex ecosystem that plays crucial role in promoting the interaction between body and its environment. It has been increasingly recognized diverse physiological functions. Recent studies have shown close association development of certain tumors, including leukemia. Leukemia malignant clonal disease characterized by uncontrolled growth one or more types blood cells, which most common cancer children. imbalance linked to pathological mechanisms Probiotics, are beneficial microorganisms help maintain balance host microbiome, play regulating microbiota. Probiotics potential assist treatment leukemia improve clinical prognosis patients. This study reviews relationship microbiota, probiotics, progression based on current research. In addition, utilizing zebrafish models future might reveal specific their interactions, thereby providing new insights into conclusion, further investigation still needed fully understand accurate microbes

Language: Английский

Citations

4