Viruses,
Journal Year:
2024,
Volume and Issue:
16(11), P. 1737 - 1737
Published: Nov. 5, 2024
This
study
provides
an
in-depth
analysis
of
mpox,
encompassing
its
history,
characteristics,
epidemiology,
diagnostics,
treatment
options,
and
the
ongoing
evolution
virus
transmission
dynamics.
Mpox,
though
once
successfully
eradicated,
has
re-emerged
with
new
modes
a
broader
host
range.
Genomic
analyses
have
revealed
virus's
adaptability,
posing
challenges
for
diagnostics
vaccine
efficacy.
The
epidemiology
shifted
from
sporadic
zoonotic
in
rural
Africa
to
significant
presence
urban
areas,
particularly
impacting
high-risk
populations.
Advancements
therapeutics
offer
hope,
but
persist.
work
underscores
critical
need
enhanced
surveillance,
vaccination
strategies,
continued
research
bolster
global
health
systems
preparedness
future
outbreaks.
Canadian Journal of Infectious Diseases and Medical Microbiology,
Journal Year:
2025,
Volume and Issue:
2025(1)
Published: Jan. 1, 2025
The
monkeypox
(Mpox)
virus
has
emerged
as
a
global
public
health
emergency
of
international
concern
recently.
that
was
endemic
in
West
and
Central
Africa
now
been
reported
with
chains
transmission
to
several
countries.
A
scoping
review
carried
out
from
the
relevant
literature
available
PubMed,
Scopus
Web
Science.
This
comprehensive
analysis
describes
epidemiology,
pathogenesis,
clinical
manifestations,
complications
including
secondary
bacterial
infections,
diagnosis,
treatment
vaccination.
article
underscores
significance
key
viral
immune
mediators
infection
discusses
updated
recommendations
on
therapeutic
strategies
Small Structures,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 19, 2025
To
effectively
address
crisis
emergence
of
new
virus
such
as
monkeypox,
a
collective
and
collaborative
effort
between
scientists,
engineers,
innovators,
artists
from
all
ages,
regions,
diverse
fields
is
required.
This
review
explores
holistic
approach
to
addressing
the
monkeypox
by
integrating
nanobiosensors,
artificial
intelligence,
visual
arts,
humanities,
social
sciences.
Traditional
diagnostic
methods
are
often
limited
time,
accessibility,
accuracy,
but
advancement
point‐of‐care
smart
nanobiosensors
offers
promising
shift
toward
rapid,
precise,
accessible
diagnostics.
They
enhance
ability
screen,
diagnose,
monitor
infections
efficiently,
contributing
better
disease
management.
Beyond
technological
innovation,
essential
role
sciences
in
fostering
public
engagement,
understanding,
acceptance
tools
emphasized.
Visual
arts
can
illustrate
scientific
concepts,
making
them
more
relatable,
while
storytelling
through
various
media
reduce
stigma
promote
preventive
measures.
Social
provide
insights
into
cultural
attitudes,
behaviors,
health
challenges,
ensuring
that
solutions
integrated
communities.
By
combining
these
disciplines,
this
presents
comprehensive
framework
for
resilient
global
system
aligns
with
One
Health
principles,
emphasizing
interconnectedness
human,
animal,
environmental
health.
Allergy,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 4, 2024
Abstract
As
the
world
still
vividly
recalls
previous
monkeypox
(mpox)
outbreak
that
impacted
over
120
countries
worldwide
with
more
than
99,000
cases
in
2022,
we
are
now
facing
a
second
wave
of
infections
from
virus
(MPXV),
characterized
by
an
exponential
increase
cases.
The
current
2024
has
already
recorded
20,000
Africa,
marking
dramatic
escalation
compared
to
outbreaks.
predominance
newly
identified
clade
Ib
variant,
first
detected
Democratic
Republic
Congo
(DRC)
and
across
multiple
African
nations
beyond,
underscores
its
enhanced
transmissibility
potential
for
international
spread,
evidenced
Sweden
Thailand.
World
Health
Organization
(WHO)
declared
on
August
14,
2024,
mpox
Public
Emergency
International
Concern
(PHEIC),
calling
heightened
global
public
health
measures.
ongoing
pattern
unusual,
frequent,
extensive
outbreaks
implications
poses
significant
questions.
This
review
addresses,
format
50
questions
answers,
outbreak,
detailing
characteristics,
epidemiological
data,
impact
It
comprehensively
explores
critical
related
MPXV
virological
immunological
response,
clinical
manifestations,
epidemiology,
diagnostics,
available
treatments.
also
documents
evolving
challenges
posed
highlighting
scale,
response.
Journal of Innate Immunity,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 13, 2024
The
re-emergence
of
the
Mpox
(formerly
monkeypox)
in
2022
non-endemic
countries
has
raised
many
concerns
for
global
health
due
to
its
high
transmissibility
and
mortality
rate.
A
major
challenge
fighting
is
ability
evade
host's
innate
immune
system,
which
first
line
defense
against
viral
infections.
encodes
various
proteins
that
interfere
with
key
antiviral
pathways
mechanisms,
such
as
nuclear
factor
kappa
B
(NF-κB)
signaling,
cytokine
production,
complement
inflammasome
activation,
chemokine
binding.
These
modulate
expression
function
mediators,
interferons,
interleukins,
toll-like
receptors,
impair
recruitment
activation
cells,
natural
killer
cells.
By
suppressing
or
altering
these
responses,
enhances
replication
infection
host
tissues
organs,
leading
systemic
inflammation,
tissue
damage,
organ
failure.
This
study
reveals
new
insights
into
molecular
cellular
interactions
between
host’s
immunity
identifies
potential
targets
strategies
interventions.
IntechOpen eBooks,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 12, 2025
Viruses
are
widely
present
in
nature
and
can
infect
eukaryotic
cells,
producing
a
variety
of
biological
effects.
Several
viruses
capable
coexisting
with
human
cells
over
the
long
term,
it
has
been
proven
that
these
possess
carcinogenic
properties.
Radiation
therapy
is
common
method
used
for
treating
tumors.
Under
influence
radiation,
infected
tumor
uninfected
exhibit
different
pathological
characteristics
treatment
outcomes.
Herein,
this
chapter,
we
discuss
impact
five
on
radiation
therapy,
including
coronavirus
disease-2019
(COVID-19),
hepatitis
B
virus
(HBV),
papillomavirus
(HPV),
monkeypox
virus,
avian
influenza
virus.
We
hope
by
summarizing
relationship
between
viral
replication
provide
novel
insight
future
treatments.
Vaccines,
Journal Year:
2024,
Volume and Issue:
12(9), P. 964 - 964
Published: Aug. 26, 2024
Monkeypox
(Mpox)
is
a
zoonotic
disease
caused
by
monkeypox
virus
(MPXV),
an
Orthopoxvirus
(OPXV).
Since
we
are
observing
the
first
MPXV
outbreak
outside
African
continent,
general
population
probably
does
not
have
pre-existing
memory
response
for
but
may
immunity
against
previous
smallpox
vaccine
based
on
live
replicating
Vaccinia
strain
(VACV).
Using
whole
blood
platform,
aim
to
study
MPXV-
T-cell-specific
in
Mpox-cured
subjects.
