Evaluation of Genotoxicity and Mutagenicity in Amphibian Species that Inhabit Agroecosystem Environments DOI
Marcelino Benvindo‐Souza, Raquel Fernanda Salla, Daniela de Melo e Silva

et al.

Royal Society of Chemistry eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 59 - 80

Published: Dec. 18, 2023

Agrochemical residues affect the sustainability of agroecosystems and compromise health many amphibians other living species, including humans. To monitor environment, biomarkers genotoxicity [such as comet or single cell electrophoresis assay (CA)] mutagenicity micronucleus (MN)] test can be efficient tools to estimate early effects agrochemical pollution. Thus, present study evaluated factors that indicate in three Neotropical amphibian species inhabit agroecosystems. We reviewed data from South American studies conducted on used situ approaches with anuran species. analyzed 256 manuscripts indexed Web Science, Scopus Google Scholar databases, which 19 papers were selected. Studies mainly led by Argentina, Brazil Colombia. Notably, most frequently studied lesser frog Dendropsophus minutes (Hylidae), barker Physalaemus cuvieri (Leptodactylidae) common Rhinella arenarum (Bufonidae). Overall, found agricultural areas showed a higher frequency DNA damage CA MN tests compared reference (controls). Fifty-six formulations agrochemicals reported, insecticides, herbicides, fungicides fertilizers (e.g., nitrate phosphorus). Given sensitivity these anurans chemical compounds, new should encouraged agroecosystem areas.

Language: Английский

Ecotoxicological impacts associated with the interplay between micro(nano)plastics and pesticides in aquatic and terrestrial environments DOI
Muhammad Junaid, Zohaib Abbas, Junaid Ali Siddiqui

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 165, P. 117133 - 117133

Published: June 17, 2023

Language: Английский

Citations

31
Environmental toxin chlorpyrifos induces liver injury by activating P53-mediated ferroptosis via GSDMD-mtROS DOI Creative Commons

Chenyang Han,

Jian Sheng, Hongyan Pei

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2023, Volume and Issue: 257, P. 114938 - 114938

Published: April 24, 2023

We investigate the mechanism whereby chlorpyrifos (CHI), an environmental toxin, causes liver injury by inducing ferroptosis in hepatocytes.The toxic dose (LD50 = 50 μM) of CHI for AML12 normal mouse hepatocytes was determined, and ferroptosis-related indices were measured, including levels SOD, MDA GSH-Px, as well cellular content iron ions. JC-1 DCFH-DA assays employed to detect mtROS levels, mitochondrial proteins (GSDMD, NT-GSDMD), (P53, GPX4, MDM2, SLC7A11). knocked out GSDMD P53 observed CHI-induced ALM12 after applying YGC063, ROS inhibitor. In animal experiments, we explored effect on using conditional GSDMD-knockout mice (C57BL/6 N-GSDMDem1(flox)Cya) inhibitor Fer-1. Small molecule-protein docking Pull-down assay verify association between GSDMD.We found that could induce AML12. promoted cleavage GSDMD, leading upregulation NT-GSDMD expression, levels. activation ferroptosis. Knock inhibit ferroptosis, YGC063 also knockout or Fer-1 intervention significantly injury. binding its SER234 site.CHI can bind promote cleavage, while open membrane release. Cytoplasmic facilitate P53-mediated GSDMD-mtROS is primary induces hepatocytes.

Language: Английский

Citations

15
Risk evaluation and prioritization of contaminants of emerging concern and other organic micropollutants in two river basins of central Argentina DOI
Lidwina Bertrand, Fernando G. Iturburu, María Eugenia Valdés

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 878, P. 163029 - 163029

Published: March 27, 2023

Language: Английский

Citations

13
Protocol for pesticide residue monitoring and risk assessment on water, sediment, and fish: a case study of two selected reservoirs in Ghana DOI Creative Commons
Abdou Orou-Seko, Dennis Chirawurah, Jean-Pierre Gnimatin

et al.

Heliyon, Journal Year: 2024, Volume and Issue: unknown, P. e37251 - e37251

Published: Sept. 1, 2024

Language: Английский

Citations

5
Assessing and mitigating foodborne acetochlor exposure induced ileum toxicity in broiler chicks: The role of omega-3 polyunsaturated fatty acids supplementation and molecular pathways analysis DOI
Yue Zhang, Enyu Zhang, Lulu Hou

et al.

Pesticide Biochemistry and Physiology, Journal Year: 2023, Volume and Issue: 199, P. 105761 - 105761

Published: Dec. 30, 2023

Language: Английский

Citations

11
Assessment of Land Ecological Security Based on the Boston Model: A Case Study from China DOI Creative Commons
Yingchao Li,

Zhongkang Lian,

Tianlin Zhai

et al.

Land, Journal Year: 2023, Volume and Issue: 12(7), P. 1348 - 1348

Published: July 6, 2023

Land resources are essential natural and strategic economic for human survival development. However, improper use has brought unprecedented pressure challenges to the ecosystem. Therefore, assessment analysis of land ecological security status identification diagnosis obstacles affecting helpful avoid problems caused by at source provide a theoretical basis sustainable construction civilization in China. Based on data from 2006 2020, this study constructed risk-evaluation index system health-evaluation system. AHP, entropy method, combination weighting TOPSIS model, Boston matrix obstacle degree model were used assess situation Nanyang City analyze factors. The results show following: (1) during period, risk value exhibited Kuznets inverted “U” curve change, while health showed change; (2) overall level gradually improved, with pattern “relatively safe (2006–2020)–unsafe (2011–2016)–relatively (2017–2019)–safe (2020)”; (3) main factors ecosystem erosion area, sewage discharge, area waterlogging control, grain sown coverage urban green built-up farmland effective irrigated area.

Language: Английский

Citations

8
Impact of thermal cooking processes on organochlorine pesticide residues (OCPs) in the edible green seaweed, Ulva lactuca, and associated human health risk assessment DOI

Shanmugam Sundhar,

R. Jeya Shakila,

Rajendran Shalini

et al.

Journal of Food Composition and Analysis, Journal Year: 2023, Volume and Issue: 121, P. 105370 - 105370

Published: May 4, 2023

Language: Английский

Citations

7
Degree of human activity exert differentiated influence on conventional and emerging pollutants in drinking water source DOI
Ke Wu, Kangping Cui, Yuansheng Huang

et al.

Environmental Science and Pollution Research, Journal Year: 2023, Volume and Issue: 31(5), P. 7214 - 7226

Published: Dec. 29, 2023

Language: Английский

Citations

5
Synergistic Toxic Effects and Mechanistic Insights of Beta-cypermethrin and Pyraclostrobin Exposure on Hook Snout Carp (Opsariichthys bidens): A Biochemical, Transcriptional, and Molecular Approach DOI
Yihan Wang, Zhaoyu Li, Chun Ji

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 358, P. 124535 - 124535

Published: July 11, 2024

Language: Английский

Citations

1
Occurrence of pesticide residues and associated ecological risks assessment in water and sediment from selected dams in northern Ghana DOI Creative Commons
Abdou Orou-Seko, Dennis Chirawurah,

Alexis Houndji

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(10), P. e0312273 - e0312273

Published: Oct. 21, 2024

Pesticides are chemicals used to enhance crop production. However, their residues can persist and accumulate in various environmental settings. This study assessed the occurrence of pesticide ecological risks surface water sediment from Libga Builpela dams northern Ghana. A total 42 pesticides were analysed. Toxic units assess acute risk sediment-dwelling organisms aquatic biota. Risk quotients employed chronic organisms. Chlorpyrifos, atrazine, profenofos, chlorfenvinphos main found water. The concentrations highest near dam (0.413μg/L, 2.927μg/L, 0.304μg/L, 0.692μg/L, 0.073μg/L, 0.290μg/L, 0.06μg/L, absent dam). In sediment, organophosphates pyrimiphos-methyl chlorpyrifos at high concentrations. They higher quantities (0.554mg/kg 0.052mg/kg, respectively) (0.051mg/kg 0.043mg/kg, respectively). For organochlorines, p,p’-DDE p,p’-DDD detected for than p,p’-DDE. Additionally, atrazine this study. toxic showed a that live as result chlorpyrifosfos residues. Similarly, pirimiphos-methyl chlorfenvinphos, followed by chlorpyrifos, contributed invertebrates. both had long-term life; however, was due Pirimiphos-methyl Chlorfenvinphos. Ghana’s regulations less comprehensive enforcement is often weaker protecting It recommended enforce strict limits on there need regularly review update these based new scientific data protect ecosystems.

Language: Английский

Citations

1