Heavy metal(loid) bioaccumulation in fish and its implications for human health DOI Creative Commons
Dhary Alewy Almashhadany,

Rzgar Farooq Rashid,

K. I. Altaif‎

et al.

Italian Journal of Food Safety, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 20, 2024

Heavy metal(loid)s (HM) pollution in aquatic environments is a serious issue due to the toxicity, persistence, bioaccumulation, and biomagnification of these pollutants. The main sources HM contamination are industrial activities, mining, agricultural practices, combustion fossil fuels. Fish can accumulate HMs through process called bioaccumulation. As larger predatory fish consume smaller fish, enter food chains become increasingly concentrated their tissues finally reach humans. Here, we provided general concise conclusion from current research findings on toxicological effects different body systems. Exposure lead range adverse health effects, including neurological damage, developmental disorders, kidney cardiovascular problems, cancers. Their long-term accumulation result chronic toxicity even at low levels exposure. exert cellular cytotoxicity by disrupting essential processes structures. They interfere with enzyme function, disrupt cell membrane integrity, induce oxidative stress, cause DNA ultimately leading death or dysfunction. Prevention control involve implementing measures reduce release into environment regulations processes, waste management, technologies. Additionally, monitoring remediation efforts crucial for identifying contaminated sites strategies such as soil water human exposure mitigate impact ecosystems. To conclude, poses risks public environment, necessitating urgent interdisciplinary harmful promote sustainable practices that flow biological

Language: Английский

Associations between exposure to brominated flame retardants and hyperlipidemia risk in U.S. Adults DOI Creative Commons
Jun‐Ping Liu, Zhaoyue Liu, Xinru Liu

et al.

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 12, 2025

Environmental exposure to toxic brominated flame retardants (BFRs) has been confirmed have detrimental effects on human health. The impact of serum BFRs hyperlipidemia risk not sufficiently examined. Our objective is identify both the individual and combined further investigate most influential chemicals. We included 7,009 individuals with complete details 9 types BFRs, hyperlipidemia, other covariates from NHANES in 2007–2016. Multivariate logistic regression was conducted evaluate risk. assessed cumulative effect through weighted quantile sum (WQS) regression, g-computation (QGC), Bayesian kernel machine models. PBDE 28, 47, 85, 99, 100, 154, 209, PBB153 were found be positively associated results WQS QGC revealed consistent positive correlation. PBDE209 emerged as significant chemicals exerting influence. restricted cubic splines identified dose-response relationship. Exposure an increased hyperlipidemia. causal relationship still requires confirmation large-scale cohort studies.

Language: Английский

Citations

1
Biopolymer‑carbonaceous composites, progress, and adsorptive mitigation of water pollutants DOI

Ibrahim Khan,

Nisar Ali, Yan Jin

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 274, P. 133379 - 133379

Published: June 25, 2024

Language: Английский

Citations

8
Is inflammation a missing link between relative handgrip strength with hyperlipidemia? Evidence from a large population-based study DOI Creative Commons
Rui La,

Yunfei Yin,

Wenquan Ding

et al.

Lipids in Health and Disease, Journal Year: 2024, Volume and Issue: 23(1)

Published: May 27, 2024

Abstract Background Relative handgrip strength (RHGS) was positively correlated with healthy levels of cardiovascular markers and negatively metabolic disease risk. However, its association hyperlipidemia remains unknown. The present study investigated the link between RHGS hyperlipidemia, utilizing data from National Health Nutrition Examination Survey (NHANES) further examined hypothesis that inflammation may serve a mediating role within this relationship. Methods Data were extracted 4610 participants in NHANES database spanning 2011–2014 to explore correlation using multivariate logistic regression models. Subgroup analyses conducted discern across diverse populations. Additionally, smooth curve fitting threshold effect analysis validate hyperlipidemia. Furthermore, potential on also explored. Results According fully adjusted model, [odds ratio (OR) = 0.575, 95% confidence interval (CI) 0.515 0.643], which consistently significant all populations, notably among women. Smooth substantiated negative Moreover, effects indicated white blood cell (WBC) count, neutrophil (Neu) lymphocyte (Lym) count played roles as mediators, mediation ratios 7.0%, 4.3%, 5.0%, respectively. Conclusions This identified prominent Elevated protective factor against potentially through mechanisms underlying modulation inflammatory processes.

Language: Английский

Citations

4
Association between Blood Trihalomethane Concentrations and the Risk of Dyslipidemia: Nationally Representative Cross-Sectional Study DOI
Zihao Xu,

Xu-Lian Tang,

Hong-Xuan Huang

et al.

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 24, 2025

Experimental studies have indicated that exposure to disinfection byproducts (DBPs) may affect the lipid synthesis. However, epidemiological evidence is sparse. This study aimed investigate relationship between blood trihalomethane (THM) and risk of dyslipidemia from National Health Nutrition Examination Survey 2005–2018. We included adults (n = 16,159) whose concentrations chloroform (TCM), bromodichloromethane (BDCM), dibromochloromethane (DBCM), bromoform (TBM) were quantified. Multivariable logistic regression revealed significantly elevated risks in highest group TCM [adjusted odds ratios (ORs) 1.30, 95% confidence intervals (CIs): 1.15–1.47], BDCM (1.23,1.07–1.42), TBM (1.35, 1.08–1.68), total THMs (TTHMs; sum all four THMs) (1.30, 1.14–1.48). In subgroup analysis, these associations stronger among young/middle-aged individuals. Weighted Quantile Sum G-Computation combined THM was positively associated with risk. Our provides new a positive association dyslipidemia, underscoring need for further research confirm findings explore underlying mechanisms.

Language: Английский

Citations

0
The association between low-concentration heavy metal exposure and chronic kidney disease risk through α-klotho DOI Creative Commons
Sishi Liu, Wang Hq,

Yifei Cao

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 2, 2025

Language: Английский

Citations

0
Individual and combined contamination of the toxic metals in commercial cat and dog food DOI Creative Commons

Jiaying Du,

Kerui Zhou,

Han Jiang

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 17, 2025

As the long-term accumulation of toxic metals in food poses significant health risks to pets, there is a growing concern among people regarding metal contamination pet food. In order investigate levels China, we collected total 93 imported cat and dog from Chinese market produced 2021-2022, comprising 45 48 food, determined concentrations lead (Pb), cadmium (Cd), chromium (Cr), mercury (Hg) arsenic (As) them. The Pb, Cd Cr were by flame atomic absorption spectrometry, while Hg quantified fluorescence spectrometry. most contaminated all samples As, which detected samples, followed Hg, was 91 samples. prevalent metals, found Pb not canned both foods showed relatively high rates Cr, Hg. had highest dry Some exceed limits set Hygienical Standard for Pet Feed China (Announcement No. 20 2018) other remained within acceptable limits. Canned however, met regulatory metals. Across types consistently combined contaminants. Analysis acute hazard index (aHI) values that cats dogs face potential dietary exposure investigated, with posing risk, As. This study underscores extensive presence foods, risk due ongoing multiple

Language: Английский

Citations

0
Associations of Urinary Heavy Metal Mixtures with High Remnant Cholesterol among US Adults: Evidence from the National Health and Nutrition Examination Survey (1998–2018) DOI Creative Commons
Hui Li,

Bei-Jing Cheng,

Peiyan Yang

et al.

Toxics, Journal Year: 2024, Volume and Issue: 12(6), P. 430 - 430

Published: June 13, 2024

The main objective of our study is to explore the associations between combined exposure urinary heavy metals and high remnant cholesterol (HRC), a known cardiovascular risk factor. Utilizing data from National Health Nutrition Examination Survey (NHANES) 1999 2018, we conducted cross-sectional analysis 5690 participants, assessing concentrations ten metals. Ten in urine were measured by inductively coupled plasma mass spectrometry (ICP-MS). Fasting residual ≥0.8 mmol/L was defined as HRC (using blood samples). Statistical analyses included weighted multivariable logistic regression, quantile sum (WQS) g-computation (qgcomp), Bayesian kernel machine regression (BKMR) evaluate metal with HRC. Stratified based on individual characteristics also conducted. Multivariable found that four (OR Q4 vs. Q1: 1.33, 95% CI: 1.01–1.75 for barium (Ba); OR 1.50, 1.16–1.94 cadmium (Cd); 1.52, 1.15–2.01 mercury (Hg); 1.35, 1.06–1.73 lead (Pb)) positively correlated elevated after adjusting covariates. In addition, all three mixed models, including WQS (OR: 1.25; 1.07–1.46), qgcomp 1.17; 1.03–1.34), BKMR, consistently showed significant positive correlation co-exposure mixtures HRC, Ba Cd being contributors within mixture. These more pronounced younger adults (20 59 years), males, those higher body index status (≥25 kg/m2). Our findings reveal relationship mixture among US adults, major mixture’s overall effect. Public health efforts aimed at reducing can help prevent and, turn, disease.

Language: Английский

Citations

2
Association between organophosphate esters individual and mixed exposure with the risk of hyperlipidemia and serum lipid levels among adults in Wuhan, China DOI
Qitong Xu, Chang Xie, Sijie Yang

et al.

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(35), P. 48629 - 48640

Published: July 22, 2024

Language: Английский

Citations

1
The association between dietary carbohydrate intake and the risk of hyperlipidemia among reproductive-aged women in the US: A cross-sectional study DOI Creative Commons

Minli Zhao,

Qiuping Zhang,

Yuan Lin

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(10), P. e0310184 - e0310184

Published: Oct. 16, 2024

The association between dietary carbohydrate intake and hyperlipidemia remained incompletely understood. This study aimed to explore the risk of among reproductive-aged women in US.

Language: Английский

Citations

1
Campomanesia xanthocarpa (Mart.) O. Berg: Therapeutic potential through a comprehensive review of biological activities and phenolic compound interactions DOI
Vanessa Ruana Ferreira da Silva, Aniela Pinto Kempka

Biocatalysis and Agricultural Biotechnology, Journal Year: 2023, Volume and Issue: 54, P. 102927 - 102927

Published: Nov. 1, 2023

Language: Английский

Citations

3