YUCOMAT 2023: An International Advisory Board Member’s Digest DOI Creative Commons
Vuk Uskoković

Published: Oct. 24, 2023

The 24th edition of the Yugoslav Conference on Materials (YUCOMAT) organized annually by Research Society Serbia (MRS-Serbia) was held in Herceg Novi, Montenegro, from 4 September to 8 2023. conference attracted 212 participants and nearly 200 presenters, 17 which were plenary speakers, while rest assigned regular oral or poster presentations. came over 20 different countries world, most represented among Serbia, Ukraine, Poland, Czech Republic, United States, Lithuania, Italy, Republic Korea, Romania, Germany, China. Outside five sessions at YUCOMAT a special session dedicated MXenes, divided symposia: (i) advanced methods synthesis processing materials; (ii) materials for high-technology applications; (iii) nanostructured (iv) eco-materials eco-technologies; (v) biomaterials. In this report, member International Advisory Board MRS-Serbia gives digest conference, alongside providing few historical remarks.

Language: Английский

Nanovaccines: A game changing approach in the fight against infectious diseases DOI Open Access

Priyanka Choudhary,

Mai Abdel Haleem Abusalah, Hitesh Chopra

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2023, Volume and Issue: 167, P. 115597 - 115597

Published: Sept. 30, 2023

The field of nanotechnology has revolutionised global attempts to prevent, treat, and eradicate infectious diseases in the foreseen future. Nanovaccines have proven be a valuable pawn this novel technology. are made up nanoparticles that associated with or prepared components can stimulate host's immune system. In addition their delivery capabilities, nanocarriers been demonstrated possess intrinsic adjuvant properties, working as cell stimulators. Thus, nanovaccines potential promote rapid well long-lasting humoral cellular immunity. several possible benefits, including site-specific antigen delivery, increased bioavailability, diminished adverse effect profile. To avail these nanoparticle-based vaccines being developed, virus-like particles, liposomes, polymeric nanoparticles, nanogels, lipid emulsion vaccines, exomes, inorganic nanoparticles. Inspired by distinctive researchers on development for variety applications, such cancer immunotherapy diseases. Although few challenges still need overcome, modulation nanoparticle pharmacokinetics avoid elimination from bloodstream reticuloendothelial system, future prospects technology also assuring, multiple options personalised needle-free formulations, combination promising candidates.

Language: Английский

Citations

79

Warning on the inhalation of silica nanoparticles: experimental evidence for its easy passage through the air-blood barrier, resulting in systemic distribution and pathological injuries DOI
Hailin Xu,

Yurou Zhu,

Lingnan Zhu

et al.

Chemico-Biological Interactions, Journal Year: 2025, Volume and Issue: unknown, P. 111423 - 111423

Published: Feb. 1, 2025

Language: Английский

Citations

1

Nano-based carriers for pulmonary drug delivery: A review on the available drug delivery applications and toxicity issues DOI
Panoraia I. Siafaka, Ece Özcan Bülbül, Αndroulla N. Miliotou

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 92, P. 105381 - 105381

Published: Jan. 20, 2024

Language: Английский

Citations

9

State-of-the-Art Review on Inhalable Lipid and Polymer Nanocarriers: Design and Development Perspectives DOI Creative Commons
Gabriella Costabile, Gemma Conte,

Susy Brusco

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(3), P. 347 - 347

Published: March 1, 2024

Nowadays, the interest in research towards local administration of drugs via inhalation route is growing as it enables direct targeting lung tissue, at same time reducing systemic side effects. This great significance era nucleic acid therapeutics and personalized medicine for treatment severe diseases. However, success any therapy driven by a delicate interplay factors, such physiochemical profile payload, formulation, device, aerodynamic properties, interaction with fluids. The development drug delivery systems tailored to needs this central its revolutionize respiratory With review, we aim provide an up-to-date overview advances nanoparticulate carriers special regard concerning lipid polymer-based nanocarriers (NCs). Starting from biological barriers that anatomical structure imposes, need be overcome, current strategies achieve efficient best support NCs are highlighted.

Language: Английский

Citations

8

Magical spherical particles produced by centrifugal atomization DOI Creative Commons
Dragan Uskoković, Vuk Uskoković

Powder Technology, Journal Year: 2024, Volume and Issue: 444, P. 120017 - 120017

Published: Aug. 1, 2024

Centrifugal atomization by the rotating electrode process enables production of powders with perfectly spherical particles. In this article, history centrifugal and selected recent innovations in particle processing technology are discussed. Numerous materials applications directly benefitting from highlighted. Traditionally, has included alloys titanium, tungsten, molybdenum other metals, which continue to be widely applied high technologies. More up-and-coming discussed include uranium-based fuels for nuclear fission reactors, neutron multipliers fusion magnetocaloric converting gaseous into liquid hydrogen. addition review obtained these distinct using process, fundamental principles governing mechanism formation particles constituting such elaborated. Key limitations method also alongside present future directions innovation inspired desire solve them.

Language: Английский

Citations

3

Particulate platform for pulmonary drug delivery: Recent advances of formulation and fabricating strategies DOI
Zhibin Zhang, Mengya Jin, Xinyu Yang

et al.

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 125601 - 125601

Published: April 1, 2025

Language: Английский

Citations

0

Unlocking the potential of remdesivir: innovative approaches to drug delivery DOI Creative Commons
Maie S. Taha, Ahsan R. Akram,

Ghada A. Abdelbary

et al.

Drug Delivery and Translational Research, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

Abstract Given the recurrent waves of COVID-19 and emergence new viral infections, optimizing potential remdesivir as an antiviral agent is critical. While several reviews have explored efficacy remdesivir, few comprehensively addressed its challenges, such necessity for intravenous infusion, suboptimal lung accumulation, safety concerns related to formulation. This review critically examines these challenges while proposing innovative solutions effective combinations with other agents repurposed drugs. By highlighting role complex generics, we aim enhance therapeutic in ways not previously discussed existing literature. Furthermore, address development novel drug delivery systems which specifically improve remdesivir's pharmacological profile. analyzing recent findings, assess both successes limitations current approaches, providing insights into ongoing strategies further optimization. uniquely focuses on targeted formulations, thereby maximizing benefits broadening application combating emerging threats. In doing so, fill a critical gap literature, offering comprehensive overview that informs future research clinical strategies. Graphical

Language: Английский

Citations

0

Antioxidants in cancer therapy mitigating lipid peroxidation without compromising treatment through nanotechnology DOI Creative Commons
Daniel Ejim Uti, Item Justin Atangwho, Esther Ugo Alum

et al.

Discover Nano, Journal Year: 2025, Volume and Issue: 20(1)

Published: April 24, 2025

Cancer treatments often exploit oxidative stress to selectively kill tumour cells by disrupting their lipid peroxidation membranes and inhibiting antioxidant enzymes. However, plays a dual role in cancer progression, acting as both promoter suppressor. Balancing through therapy remains challenge, excessive activity may compromise the efficacy of chemotherapy radiotherapy. This review explores antioxidants mitigating while maintaining treatment efficacy. It highlights recent advancements nanotechnology-based targeted delivery optimize therapeutic outcomes. A comprehensive literature was conducted using reputable databases, including PubMed, Scopus, Web Science, ScienceDirect. The search focused on publications from past five years (2020-2025), supplemented relevant studies earlier years. Keywords such "antioxidants," "lipid peroxidation," "nanotechnology therapy," "oxidative stress" were utilized. Relevant articles critically analysed, graphical illustrations created. Emerging evidence suggests that nanoparticles, liposomes, polymeric metal-organic frameworks, others, can effectively encapsulate control release minimizing systemic toxicity. Stimuli-responsive carriers with tumour-specific targeting mechanisms further enhance delivery. Studies indicate these strategies help preserve normal cells, mitigate stress-related damage, improve challenges bioavailability, stability, potential interactions standard therapies remain. Integrating nanotechnology antioxidant-based interventions presents promising approach for optimizing therapy. Future research should focus refining modulation strategies, assessing profiles during treatment, employing biomarkers determine optimal dosing. balanced use adverse effects.

Language: Английский

Citations

0

Advances in the study of silica nanoparticles in lung diseases DOI

Li-Hong Ao,

Yungeng Wei,

Hong-Ru Tian

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 912, P. 169352 - 169352

Published: Dec. 16, 2023

Language: Английский

Citations

4

Evaluating Molecular Mechanism of Viral Inhibition of Aerosolized Smart Nano-Enabled Antiviral Therapeutic (SNAT) on SARS-CoV-2-Infected Hamsters DOI Creative Commons

Anais N. Bauer,

John F. Williams, Lok R. Pokhrel

et al.

Toxics, Journal Year: 2024, Volume and Issue: 12(7), P. 495 - 495

Published: July 5, 2024

Smart Nano-enabled Antiviral Therapeutic (SNAT) is a promising nanodrug that previously demonstrated efficacy in preclinical studies to alleviate SARS-CoV-2 pathology hamsters. SNAT comprises taxoid (Tx)-decorated amino (NH

Language: Английский

Citations

1