Comment on Narsale et al. Th2 cell clonal expansion at diagnosis in human type 1 diabetes. Clin Immunol. 2023 Oct 29 DOI
Marcelo Maia Pinheiro, Felipe Moura Maia Pinheiro, Susana Nogueira Diniz

et al.

Clinical Immunology, Journal Year: 2023, Volume and Issue: 258, P. 109873 - 109873

Published: Dec. 19, 2023

Language: Английский

Application and Progression of Single‐Cell RNA Sequencing in Diabetes Mellitus and Diabetes Complications DOI Creative Commons

Jiajing Hong,

Shiqi Lu,

Guohui Shan

et al.

Journal of Diabetes Research, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

Diabetes is a systemic metabolic disorder primarily caused by insulin deficiency and resistance, leading to chronic hyperglycemia. Prolonged diabetes can result in damage multiple organs, including the heart, brain, liver, muscles, adipose tissue, thereby causing various fatal complications such as diabetic retinopathy, cardiomyopathy, nephropathy. Single‐cell RNA sequencing (scRNA‐seq) has emerged valuable tool for investigating cell diversity pathogenesis of identifying potential therapeutic targets or complications. This review provides comprehensive overview recent applications scRNA‐seq diabetes‐related researches highlights novel biomarkers immunotherapy with cell‐type information its associated

Language: Английский

Citations

0
The potential therapeutic role of IL-35 in pathophysiological processes in type 1 diabetes mellitus DOI

Heba H. Bakery,

Heba A A Hussein,

Osama M. Ahmed

et al.

Cytokine, Journal Year: 2024, Volume and Issue: 182, P. 156732 - 156732

Published: Aug. 9, 2024

Language: Английский

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1
Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes DOI Creative Commons
Anne Eugster, Anna Lorenc, Martín Kotrulev

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Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Oct. 29, 2024

Language: Английский

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Type 1 diabetes: immune pathology and novel therapeutic approaches DOI
Eleanor Ling, Joana Lemos, Khemraj Hirani

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Diabetology International, Journal Year: 2024, Volume and Issue: 15(4), P. 761 - 776

Published: Sept. 11, 2024

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0
Comment on Narsale et al. Th2 cell clonal expansion at diagnosis in human type 1 diabetes. Clin Immunol. 2023 Oct 29 DOI
Marcelo Maia Pinheiro, Felipe Moura Maia Pinheiro, Susana Nogueira Diniz

et al.

Clinical Immunology, Journal Year: 2023, Volume and Issue: 258, P. 109873 - 109873

Published: Dec. 19, 2023

Language: Английский

Citations

0