Clinical Nutrition ESPEN, Journal Year: 2024, Volume and Issue: 61, P. 8 - 14
Published: March 7, 2024
Language: Английский
Nutrients, Journal Year: 2023, Volume and Issue: 15(6), P. 1546 - 1546
Published: March 22, 2023
Low-grade inflammation alters the homeostasis of organism and favors onset many chronic diseases. The global growth in prevalence noncommunicable diseases recent years has been accompanied by an increase consumption ultra-processed foods (UPF). Known to be hyperpalatable, economic ready-to-eat, increased UPF already recognized as a risk factor for several Different research groups have tried investigate whether could promote low-grade thus favor development Current evidence highlights adverse health effects characteristics, not only due nutrients provided diet rich UPF, but also non-nutritive components present effect they may on gut health. This review aims summarize available possible relationship between excessive modulation inflammation, potential promoters disease.
Language: Английский
Citations
105
International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(3), P. 1098 - 1098
Published: Jan. 27, 2025
This article reviews the synergistic effects of antioxidant-enriched functional foods and exercise in improving metabolic health, focusing on underlying molecular mechanisms. The review incorporates evidence from PubMed, SCOPUS, Web Science, PsycINFO, reference lists relevant up to 20 December 2024, highlighting central role Nrf2 pathway. As a critical regulator oxidative stress adaptation, mediates benefits these interventions. presents an innovative approach understanding regulation inflammation, its potential prevention treatment various diseases, including cancer, neurodegenerative disorders, cardiovascular pulmonary diabetes, inflammatory conditions, ageing, infections such as COVID-19. novelty this study is investigate bioactive compounds found (such polyphenols, flavonoids, vitamins) exercise-induced activation combined reveals their improve insulin sensitivity lipid metabolism reduce offering promising strategy for management chronic diseases. However, there are significant gaps current research, particularly regarding mechanisms interaction between diet, physical activity, activation, well long-term different populations, those with In addition, interactions other signalling pathways, AMPK, NF-κB, PI3K/Akt, collective contributions health explored. Furthermore, novel biomarkers presented assess impact strategies, NAD+/NADH ratio, GSH markers mitochondrial health. findings provide valuable insights into how integration antioxidant-rich diet regular can by activating related pathways represent strategies disorders. Further studies needed fully understand therapeutic interventions diseases stress, disease, cancer.
Language: Английский
Citations
3
European journal of medical research, Journal Year: 2025, Volume and Issue: 30(1)
Published: Jan. 31, 2025
Our research was designed to investigate the relationship between dietary inflammatory index (DII) and risk of ocular diseases, including glaucoma, cataract, age-related macular degeneration (ARMD), diabetic retinopathy. We used National Health Nutrition Examination Survey (NHANES) data from 2005 2008 conduct this study. The correlation DII diseases examined using weighted multivariable logistic regression analysis, restricted cubic spline (RCS) plots, subgroup analysis. In total, 2885 participants NHANES database were included. scores divided into four group: Q1 (- 4.438-0.386), Q2 (0.387-1.848), Q3 (1.849-3.073), Q4 (3.074-4.970). RCS shown that there a U-shaped prevalence ARMD, After adjusting for underlying confounding variables, compared group, odd ratios (ORs) with 95 percent confidence intervals (CIs) retinopathy across quartiles [0.97 (0.54, 1.75), 1.20 (0.68, 2.11), 1.29 (0.73, 2.30)], [0.87 (0.56, 1.35), 1.12 1.73), 1.16 (0.75, 1.80)], [0.85 (0.53, 1.36), 0.66 (0.40, 1.09), 0.97 (0.61, 1.56)] [0.86 (0.63, 1.18), 0.89 (0.65, 1.22), 1.04 1.45)] DII, respectively. Reducing intake pro-inflammatory foods may be an effective measure prevent onset disease, However, eating only anti-inflammatory is not best choice.
Language: Английский
Citations
2
Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11
Published: March 6, 2024
Proteins and polyphenols are abundant in the daily diet of humans their interactions influence, among other things, texture, flavor, bioaccessibility food. There two types between them: non-covalent covalent interactions, latter being irreversible more powerful. In this review, we systematically summarized advances investigation possible mechanism underlying polyphenols-proteins interaction food processing, effect different processing methods on interaction, for characterizing complexes, impacts protein structure, function nutritional value, as well potential bioavailability polyphenols. terms health promotion prepared effects such antioxidant, hypoglycemic, regulation intestinal microbiota allergic reactions have been summarized. Also, applications industry, especially foaming agents, emulsifiers nanomaterials also discussed. order to offer directions novel research systems, properties vivo , considered present challenges future perspectives topic.
Language: Английский
Citations
15
Nutraceuticals, Journal Year: 2024, Volume and Issue: 4(4), P. 522 - 561
Published: Oct. 11, 2024
Inflammation and thrombosis are implicated in several non-communicable chronic disorders, including cardiovascular diseases, diabetes, renal neurodegenerative skin especially cancer. Natural bioactives phytochemicals like phenolic compounds have been proposed to reduce the inflammatory burden with health benefits against these disorders. Vanillin is a compound found seeds of various species vanilla plants. It has known since ancient times for its aromatic soothing properties; however, recent outcomes outlined other pleiotropic actions this bioactive compound. Within article, potent anti-inflammatory activities vanillin derivatives thoroughly reviewed, emphasis on their anti-cancer, anti-infective, wound-healing, neuroprotective health-promoting properties. The mechanisms action(s), along from vitro vivo studies clinical trials, vanillin-based each specific types cancer, also outlined. Limitations future perspectives use solely as ingredients, ingredients functional products—such foods, supplements, nutraceuticals, or even cosmetics drugs—and adjuvant therapies discussed.
Language: Английский
Citations
10
American Journal of Clinical Nutrition, Journal Year: 2023, Volume and Issue: 119(1), P. 49 - 57
Published: Oct. 21, 2023
Language: Английский
Citations
15
Frontiers in Neurology, Journal Year: 2023, Volume and Issue: 14
Published: Jan. 24, 2023
Background MS is a chronic inflammatory neurological and immune-mediated disease of multifactorial etiology. Ultra-processed foods (UPFs) have been generally considered unhealthy due to their poor nutritional value. Emerging evidence suggests that factors other than content may play an additional role toward inflammation. Aim To investigate the potential association UPF consumption severity in group Italian consecutive patients. Methods Demographic (age, sex, marital status, educational level), (EDSS, MSSS), (anthropometric measures, dietary habits) information were collected. Physical activity smoking habits also investigated. Food items grouped according NOVA classification. Patients classified two groups based on (“mild” “moderate high”). Results Higher was associated with moderate-to-high compared lower both unadjusted model (OR = 2.28, 95% CI: 1.04–5.01) after adjustment for background 2.46, 1.04–5.83) clinical confounding 2.97, 1.13–7.77). Conclusions Although these results are only preliminary hypothesis generating, it important explore how various aspects diet relate order identify best strategy support patients over course.
Language: Английский
Citations
14
Nutrients, Journal Year: 2024, Volume and Issue: 16(14), P. 2313 - 2313
Published: July 18, 2024
Low-grade inflammation (LGI) mainly acted as the mediator of association obesity and inflammatory diet with numerous chronic diseases, including neuropsychiatric diseases. However, evidence about effect LGI on brain structure is limited but important, especially in context accelerating aging. This study was then designed to close gap, we leveraged a total 37,699 participants from UK Biobank utilized score (INFLA-score) measure LGI. We built longitudinal relationships INFLA-score imaging phenotypes using multiple linear regression models. further analyzed interactive effects specific covariates. The results showed high level reduced volumes subcortex cortex, globus pallidus (β [95% confidence interval] = −0.062 [−0.083, −0.041]), thalamus (−0.053 [−0.073, −0.033]), insula (−0.052 [−0.072, −0.032]), superior temporal gyrus (−0.049 [−0.069, −0.028]), lateral orbitofrontal cortex (−0.047 [−0.068, −0.027]), others. Most significant were observed among urban residents. Furthermore, males individuals physical frailty susceptive associations. provided potential insights into pathological changes during disease progression might aid development preventive control targets an age-friendly city promote great health well-being for sustainable goals.
Language: Английский
Citations
6
Dietetics, Journal Year: 2024, Volume and Issue: 3(2), P. 144 - 158
Published: May 7, 2024
Obesity is considered an important risk factor for the onset of asthma, playing a key role in enhancing disease’s severity. However, there increasing evidence linking not only obesity but also overweight with higher asthma. Although correlation between and asthma has already been reported, several aspects are still fully elucidated, mainly about inflammatory processes underlying both diseases. It well known that Western-type calorically rich diets overfeeding can act as triggers chronic metabolic inflammation, few studies have examined associations ultra-processed foods (UPFs) intake, despite its positive obesity, biomarkers inflammation. In addition to their nutrient composition, UPF may chemical additives contaminants from packaging, whose effects on health food addiction under research. this review, we provide overview current data identify obese phenotype consumption, highlighting potential central played by intestinal microbiota.
Language: Английский
Citations
5
Nutrition Reviews, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 23, 2025
Abstract It has been 15 years since the introduction of NOVA food-processing classification. While it was designed to identify ultra-processed foods linked noncommunicable diseases, system a holistic concept that fits with sustainable nutrition. However, NOVA’s connection other diet indicators not thoroughly explored. The aim summarize research and methodological context using investigate synergies discordance them. A scoping review conducted based on Preferred Reporting Items for Systematic Reviews Meta-Analyses—Extension Scoping (PRISMA-ScR). Studies published between 2009 2023 were collected from Web Science, Scopus, PubMed databases. 1612 studies initially screened; in selected (n = 77), applied addition indicator(s). analyzed within qualitative data analysis framework. 77 which healthiness 66), environmental pressure 9), affordability 11), processing classifications 6), 10) NOVA. Among them, identified relationships healthfulness synergistic majority 70/93). For indicators, mixed picture observed; classification predominantly greenhouse gas emissions 8/13), while mostly discordant fresh water use 8/12). Economic also found be 10/16). To complete nutrient profiling would beneficial healthy diets. In case integration into nutrition research, economic should controlled reach optimal trade-offs more application is gaining relevance; thus, its adaptation necessary.
Language: Английский
Citations
0