Science,
Journal Year:
2016,
Volume and Issue:
354(6315), P. 1008 - 1015
Published: Nov. 24, 2016
A
majority
of
mammalian
genes
exhibit
daily
fluctuations
in
expression
levels,
making
circadian
rhythms
the
largest
known
regulatory
network
normal
physiology.
Cell-autonomous
clocks
interact
with
light-dark
and
feeding-fasting
cycles
to
generate
approximately
24-hour
oscillations
function
thousands
genes.
Circadian
secreted
molecules
signaling
components
transmits
timing
information
between
cells
tissues.
Such
intra-
intercellular
optimize
physiology
both
by
managing
energy
use
temporally
segregating
incompatible
processes.
Experimental
animal
models
epidemiological
data
indicate
that
chronic
rhythm
disruption
increases
risk
metabolic
diseases.
Conversely,
time-restricted
feeding,
which
imposes
feeding
fasting
without
caloric
reduction,
sustains
robust
diurnal
can
alleviate
These
findings
highlight
an
integrative
role
offer
a
new
perspective
for
treating
diseases
is
hallmark.
Annual Review of Nutrition,
Journal Year:
2017,
Volume and Issue:
37(1), P. 371 - 393
Published: July 18, 2017
The
objective
of
this
review
is
to
provide
an
overview
intermittent
fasting
regimens,
summarize
the
evidence
on
health
benefits
fasting,
and
discuss
physiological
mechanisms
by
which
might
lead
improved
outcomes.
A
MEDLINE
search
was
performed
using
PubMed
terms
"intermittent
fasting,"
"fasting,"
"time-restricted
feeding,"
"food
timing."
Modified
regimens
appear
promote
weight
loss
may
improve
metabolic
health.
Several
lines
also
support
hypothesis
that
eating
patterns
reduce
or
eliminate
nighttime
prolong
nightly
intervals
result
in
sustained
improvements
human
Intermittent
are
hypothesized
influence
regulation
via
effects
(a)
circadian
biology,
(b)
gut
microbiome,
(c)
modifiable
lifestyle
behaviors,
such
as
sleep.
If
proven
be
efficacious,
these
offer
promising
nonpharmacological
approaches
improving
at
population
level,
with
multiple
public
benefits.
Circulation,
Journal Year:
2017,
Volume and Issue:
135(9)
Published: Jan. 31, 2017
Eating
patterns
are
increasingly
varied.
Typical
breakfast,
lunch,
and
dinner
meals
difficult
to
distinguish
because
skipping
snacking
have
become
more
prevalent.
Such
eating
styles
can
various
effects
on
cardiometabolic
health
markers,
namely
obesity,
lipid
profile,
insulin
resistance,
blood
pressure.
In
this
statement,
we
review
the
of
specific
patterns:
intermittent
fasting,
meal
frequency
(number
daily
occasions),
timing
occasions.
Furthermore,
propose
definitions
for
meals,
snacks,
occasions
use
in
research.
Finally,
data
suggest
that
irregular
appear
less
favorable
achieving
a
healthy
profile.
Intentional
with
mindful
attention
could
lead
healthier
lifestyle
risk
factor
management.
Endocrine Reviews,
Journal Year:
2016,
Volume and Issue:
37(6), P. 584 - 608
Published: Oct. 20, 2016
Abstract
Circadian
(∼24-hour)
timing
systems
pervade
all
kingdoms
of
life
and
temporally
optimize
behavior
physiology
in
humans.
Relatively
recent
changes
to
our
environments,
such
as
the
introduction
artificial
lighting,
can
disorganize
circadian
system,
from
level
molecular
clocks
that
regulate
cellular
activities
synchronization
between
daily
cycles
solar
day.
Sleep/wake
are
intertwined
with
global
trends
indicate
these,
too,
increasingly
subject
disruption.
A
large
proportion
world's
population
is
at
increased
risk
environmentally
driven
rhythm
sleep
disruption,
a
minority
individuals
also
genetically
predisposed
misalignment
disorders.
The
consequences
disruption
system
profound
include
myriad
metabolic
ramifications,
some
which
may
be
compounded
by
adverse
effects
on
dietary
choices.
If
not
addressed,
deleterious
will
continue
cause
widespread
health
problems;
therefore,
implementation
numerous
behavioral
pharmaceutical
interventions
help
restore
alignment
enhance
important.
Nutrition and Healthy Aging,
Journal Year:
2018,
Volume and Issue:
4(4), P. 345 - 353
Published: May 11, 2018
Time
restricted
feeding
decreases
energy
intake
without
calorie
counting
and
may
be
a
viable
option
for
weight
loss.
However,
the
effect
of
this
diet
on
body
in
obese
subjects
has
never
been
examined.This
study
investigated
effects
8-h
time
metabolic
disease
risk
factors
adults.Obese
(n
=
23)
participated
an
intervention
(ad
libitum
between
10:00
to
18:00
h,
water
fasting
h)
12
weeks.
Weight
loss
other
outcomes
were
compared
matched
historical
control
group
23).Body
decreased
(-2.6%
±
0.5;
-341
53
kcal/d)
relative
controls
over
weeks
(P
<
0.05).
Systolic
blood
pressure
(-7
2
mm
Hg)
versus
Fat
mass,
lean
visceral
fat
diastolic
pressure,
LDL
cholesterol,
HDL
triglycerides,
glucose,
insulin,
HOMA-IR,
homocysteine
not
significantly
different
from
after
(no
group×time
interaction).These
findings
suggest
that
produces
mild
caloric
restriction
loss,
counting.
It
also
offer
clinical
benefits
by
reducing
pressure.
Biology,
Journal Year:
2019,
Volume and Issue:
8(3), P. 54 - 54
Published: July 12, 2019
The
Munich
ChronoType
Questionnaire
(MCTQ)
has
now
been
available
for
more
than
15
years
and
its
original
publication
cited
1240
times
(Google
Scholar,
May
2019).
Additionally,
online
version,
which
was
until
July
2017,
produced
almost
300,000
entries
from
all
over
the
world
(MCTQ
database).
MCTQ
gone
through
several
versions,
translated
into
13
languages,
validated
against
other
objective
measures
of
daily
timing
in
independent
studies.
Besides
being
used
as
a
method
to
correlate
circadian
features
human
biology
with
factors—ranging
health
issues
geographical
factors—the
gave
rise
quantification
old
wisdoms,
like
“teenagers
are
late”,
new
concepts,
social
jetlag.
Some
MCTQ’s
simplicity
some
view
it
critically.
Therefore,
is
time
present
self-critical
on
MCTQ,
address
misunderstandings,
give
definitions
MCTQ-derived
chronotype
concept
