Aflatoxins in food: Prevalence, health effects, and emerging trends in its mitigation—An updated review

Food Safety and Health, Journal Year: 2024, Volume and Issue: 2(1), P. 39 - 71

Published: Jan. 1, 2024

Abstract Mycotoxins are secondary metabolites produced by a variety of fungal and mold species. One the mycotoxin families that is often regarded as most concerned one in human animal feeds, aflatoxin. Aflatoxins Aspergillus species very toxic cause significant contamination food supplies, resulting serious health repercussions including carcinogenicity. To date, several regulations on aflatoxin permissible level limits have been established number nations. Based government guidelines restrictions, consumers producers anticipate should not negatively impact health. Aflatoxin commodities poses consequential risk to humans also associated with substantial financial losses. Conventional reduction strategies involve both preventative decontamination approaches. The present review gives an update recent research conventional approaches, pre‐ post‐harvest procedures could potentially be used decontaminate Additionally, current study delves into source contamination, global occurrence, health, management assure security safety.

Language: Английский

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Patulin induced neuronal cell damage in human neuroblastoma SH-SY5Y Cells

Toxicology Reports, Journal Year: 2025, Volume and Issue: 14, P. 101886 - 101886

Published: Jan. 23, 2025

Language: Английский

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Markov Transition Field Combined with Convolutional Neural Network Improved the Predictive Performance of Near-Infrared Spectroscopy Models for Determination of Aflatoxin B1 in Maize

Foods, Journal Year: 2022, Volume and Issue: 11(15), P. 2210 - 2210

Published: July 25, 2022

This work provides a novel approach to monitor the aflatoxin B1 (AFB1) content in maize by near-infrared (NIR) spectra-based deep learning models that integrates Markov transition field (MTF) image coding and convolutional neural network (CNN) strategy. According data structure characteristics of spectra, new structures one-dimensional CNN (1D-CNN) two-dimensional MTF-CNN (2D-MTF-CNN) were designed construct model for monitoring AFB1 maize. The results obtained showed compared with 1D-CNN model, performance 2D-MTF-CNN had been significantly improved, its root mean square error prediction, coefficient predictive determination, relative percent deviation 1.3591 μg·kg-1, 0.9955, 14.9386, respectively. indicate MTF is an effective encoding technique converting spectra into images. It more intuitively reflects intrinsic NIR from perspective richer spectral information construction models, which can ensure detection accuracy generalization quantitative models. study analytical chemometrics analysis spectroscopy.

Language: Английский

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Emerging Alternaria and Fusarium mycotoxins in tomatoes and derived tomato products from the China market: Occurrence, methods of determination, and risk evaluation

Food Control, Journal Year: 2022, Volume and Issue: 145, P. 109464 - 109464

Published: Oct. 20, 2022

Language: Английский

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Natural Occurrence of Regulated and Emerging Mycotoxins in Wheat Grains and Assessment of the Risks from Dietary Mycotoxins Exposure in China

Toxins, Journal Year: 2023, Volume and Issue: 15(6), P. 389 - 389

Published: June 9, 2023

Wheat grains are susceptible to contamination with various natural mycotoxins including regulated and emerging mycotoxins. This study surveyed the presence of mycotoxins, such as deoxynivalenol (DON) zearalenone (ZEN), beauvericin (BEA), enniatins (ENNs ENA, ENA1, ENB, ENB1) Alternaria (i.e., alternariol monomethyl ether (AME), (AOH), tenuazonic acid (TeA), tentoxin (TEN), altenuene (ALT)) in wheat randomly collected from eight provinces across China 2021. The results revealed that each grain sample was detected at least one type mycotoxin. detection rates these ranged 7.1% 100%, average occurrence level ranging 1.11 921.8 µg/kg. DON TeA were predominant respect both prevalence concentration. Approximately 99.7% samples found contain more than toxin, co-occurrence ten toxins (DON + ZEN ENA ENA1 ENB ENB1 AME AOH TEN) most frequently combination. dietary exposure different among Chinese consumers aged 4-70 years follows: 0.592-0.992 µg/kg b.w./day for DON, 0.007-0.012 ZEN, 0.0003-0.007 BEA ENNs, 0.223-0.373 TeA, 0.025-0.041 TEN, which lower health-based guidance values mycotoxin, corresponding hazard quotient (HQ) being far 1, implying a tolerable health risk consumers. However, estimated range 0.003-0.007 b.w./day, exceeding Threshold Toxicological Concern (TTC) value 0.0025 demonstrating potential risks Therefore, developing practical control management strategies is essential controlling agricultural systems, thereby ensuring public health.

Language: Английский

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A review on recent advances in mass spectrometry analysis of harmful contaminants in food

Frontiers in Nutrition, Journal Year: 2023, Volume and Issue: 10

Published: Aug. 1, 2023

Food safety is a widespread global concern with the emergence of foodborne diseases. Thus, establishing accurate and sensitive detection methods harmful contaminants in different food matrices essential to address prevent associated health risks. Among various analytical tools, mass spectrometry (MS) can quantify multiple impurities simultaneously due high resolution accuracy achieve non-target profiling unknown pollutants food. Therefore, MS has been widely used for determination hazardous [e.g., mycotoxin, pesticide veterinary drug residues, polychlorinated biphenyls (PCBs), dioxins, acrylamide, perfluorinated compounds (PFCs) p-Phenylenediamine (PPDs) samples]. This work summarizes applications detecting matrices, discusses advantages study, provides perspective on future directions development research. With persistent occurrence novel contaminants, will play more critical role analysis.

Language: Английский

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Food Security and Foodborne Mycotoxicoses—What Should Be the Adequate Risk Assessment and Regulation?

Microorganisms, Journal Year: 2024, Volume and Issue: 12(3), P. 580 - 580

Published: March 14, 2024

The purpose of this review is to elucidate the actual threat most prevalent mycotoxins in agricultural commodities and human/animal food/feed for induction foodborne diseases or ailments. underestimated hazard combined mycotoxin uptake by animals humans critically discussed with regard synergistic additive interaction between some target mycotoxins. real toxicity combinations as it happens practice evaluated possible lower limit values control measures are suggested such cases. Some critical points on adequate risk assessment, hygiene control, regulation discussed. efficiency current regulations health hazards. assessment case multiple exposure humans/animals via suggestions proposed Appropriate food safety issues throughout supply chain order prevent diseases. preventive veterinary controls evaluations natural cases preventing contamination animal products designed human consumption avoid public issues.

Language: Английский

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Solid‐phase extraction techniques based on nanomaterials for mycotoxin analysis: An overview for food and agricultural products

Journal of Separation Science, Journal Year: 2022, Volume and Issue: 45(13), P. 2273 - 2300

Published: April 7, 2022

Mycotoxin contamination is a globally concerned problem for food and agricultural products since it may directly or indirectly induce severe threats to human health. Sensitive selective screening an efficient strategy prevent reduce animal exposure mycotoxins. However, enormous challenges exist in the determination of mycotoxins, arising from complex sample matrices, trace‐level analytes, co‐occurrence diverse Appropriate preparation essential isolate, purify, enrich mycotoxins complicated thus decreasing matrix effects lowering detection limits. With cross‐disciplinary development, new solid‐phase extraction strategies have been exploited integrated with nanotechnology meet mycotoxin analysis. This review summarizes advance progress techniques as methodological solutions Emphases are paid on nanomaterials fabricated trapping media techniques, including carbonaceous nanoparticles, metal/metal oxide‐based nanoporous materials. Advantages limitations discussed, along potential prospects.

Language: Английский

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The control of Fusarium growth and decontamination of produced mycotoxins by lactic acid bacteria

Critical Reviews in Food Science and Nutrition, Journal Year: 2022, Volume and Issue: 63(32), P. 11125 - 11152

Published: June 16, 2022

Global crop and food contamination with mycotoxins are one of the primary worldwide concerns, while there several restrictions regarding approaching conventional physical chemical decontamination methods due to nutrition loss, sensory attribute reduction in foods, residual, inconvenient operation, high cost equipment, energy consumption some methods. In this regard, overarching challenges mycotoxin crops require development biological strategies. Using certain lactic acid bacteria (LAB) as generally recognized safe (GRAS) compounds is most effective alternatives their potential release antifungal metabolites against various fungal factors species. This review highlights applications LAB biodetoxificant agents summarizes activities Fusarium growth released into food/feed. Firstly, occurrence instrumental bioanalytical for analysis were in-depth discussed. Upgraded knowledge on biosynthesis pathway produced by offers new insightful ideas clarifying function these secondary metabolites. Moreover, characterization impact from Fusarium, besides main mechanisms decontamination, covered. While thematic inhibition very complex, worth deeper investigations.

Language: Английский

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Nivalenol Mycotoxin Concerns in Foods: An Overview on Occurrence, Impact on Human and Animal Health and Its Detection and Management Strategies

Toxins, Journal Year: 2022, Volume and Issue: 14(8), P. 527 - 527

Published: July 31, 2022

Mycotoxins are secondary metabolites produced by fungi that infect a wide range of foods worldwide. Nivalenol (NIV), type B trichothecene numerous Fusarium species, has the ability to variety both in field and during post-harvest handling management. NIV is frequently found cereal cereal-based goods, its strong cytotoxicity poses major concerns for human animal health. To address these issues, this review briefly overviews sources, occurrence, chemistry biosynthesis NIV. Additionally, brief overview several sophisticated detection management techniques included, along with implications processing environmental factors on formation This review’s main goal offer trustworthy current information as mycotoxin concern foods, potential mitigation measures assure food safety security.

Language: Английский

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