Circadian Synchrony: Sleep, Nutrition, and Physical Activity.

Kelly L. Healy,

Andrew R. Morris, Andrew C. Liu

et al.

PubMed, Journal Year: 2021, Volume and Issue: 1

Published: Oct. 1, 2021

The circadian clock in mammals regulates the sleep/wake cycle and many associated behavioral physiological processes. cellular mechanism involves a transcriptional negative feedback loop that gives rise to rhythms gene expression with an approximately 24-h periodicity. To maintain system robustness, clocks throughout body must be synchronized their functions coordinated. In mammals, master is located suprachiasmatic nucleus (SCN) of hypothalamus. SCN entrained light/dark through photic signal transduction subsequent induction core expression. turn relays time-of-day information peripheral tissues. While highly responsive cues, are more sensitive non-photic resetting cues such as nutrients, temperature, neuroendocrine hormones. For example, feeding/fasting physical activity can entrain signaling pathways regulation genes proteins. As such, timing food intake matters. ideal world, cycles cycle. However, asynchronous environmental those experienced by shift workers frequent travelers, often lead misalignment between clocks. Emerging evidence suggests resulting disruption various diseases chronic conditions cause further desynchrony accelerate disease progression. this review, we discuss how sleep, nutrition, synchronize chronomedicine may offer novel strategies for intervention.

Language: Английский

The role of insufficient sleep and circadian misalignment in obesity DOI Open Access
Jean‐Philippe Chaput, Andrew W. McHill, Rebecca C. Cox

et al.

Nature Reviews Endocrinology, Journal Year: 2022, Volume and Issue: 19(2), P. 82 - 97

Published: Oct. 24, 2022

Language: Английский

Citations

286
Sleep Deprivation: Effects on Weight Loss and Weight Loss Maintenance DOI Open Access

Evangelia Papatriantafyllou,

Dimitris Efthymiou,

Evangelos Zoumbaneas

et al.

Nutrients, Journal Year: 2022, Volume and Issue: 14(8), P. 1549 - 1549

Published: April 8, 2022

This narrative review presents the findings from intervention studies on effects of sleep deprivation eating habits, metabolic rate, and hormones regulating metabolism, discusses their relevance to weight loss efforts. Disturbed sleeping patterns lead increased energy intake, partly excessive snacking, mainly foods high in fat carbohydrates. The focused duration, but also quality, dietary intake during trials, maintenance. It is important explore routines that could enhance efforts obese overweight people lose weight, maintain loss, improve overall health.

Language: Английский

Citations

56
The Impact of Meal Timing on Risk of Weight Gain and Development of Obesity: a Review of the Current Evidence and Opportunities for Dietary Intervention DOI Creative Commons
Rochelle Davis, Michelle Rogers, Alison M. Coates

et al.

Current Diabetes Reports, Journal Year: 2022, Volume and Issue: 22(4), P. 147 - 155

Published: April 1, 2022

Abstract Purpose of Review The aim this short review is to provide an updated commentary on the current literature examining impact meal timing obesity and weight gain in adults. potential mechanisms, including novel emerging factors, behind food intake across 24-h period development obesity, dietary strategies manipulating ameliorate are also explored. Recent Findings Dietary patterns that feature outside regular daytime hours can contribute circadian disruption as metabolised opposition internal daily rhythms feedback timekeeping mechanisms setting these rhythms. Epidemiological evidence late beginning suggest eating at night increases risk over time. Mechanisms contributing include changes efficiency metabolism day, dysregulation appetite hormone gut microbiota by mis-timed meals. Summary When meals eaten, relation time increasingly considered importance when implementing change order address growing burden although further research required determine optimal patterns.

Language: Английский

Citations

41
Circadian desynchrony and glucose metabolism DOI Creative Commons
Esther M. Speksnijder, Peter H. Bisschop, Sarah E. Siegelaar

et al.

Journal of Pineal Research, Journal Year: 2024, Volume and Issue: 76(4)

Published: May 1, 2024

Abstract The circadian timing system controls glucose metabolism in a time‐of‐day dependent manner. In mammals, the consists of main central clock bilateral suprachiasmatic nucleus (SCN) anterior hypothalamus and subordinate clocks peripheral tissues. oscillations produced by these different with period approximately 24‐h are generated transcriptional‐translational feedback loops set core genes. Glucose homeostasis is one daily rhythms controlled this system. pacemaker SCN through its neural projections to hypothalamic hubs that control feeding behavior energy metabolism. Using hormones such as adrenal glucocorticoids melatonin autonomic nervous system, modulates critical processes production insulin sensitivity. Peripheral tissues, liver, muscle, adipose tissue serve enhance sustain signals. optimal situation all synchronized aligned environmental light/dark cycle. A negative impact on becomes apparent when internal disturbed, also known desynchrony or misalignment. Circadian may occur at several levels, mistiming light exposure sleep will especially affect clock, whereas food intake physical activity involve clocks. review, we summarize literature investigating how it result development resistance. addition, discuss potential strategies aimed reinstating synchrony improve sensitivity contribute prevention type 2 diabetes.

Language: Английский

Citations

15
Effectiveness of Early Versus Late Time-Restricted Eating Combined with Physical Activity in Overweight or Obese Women DOI Open Access

S. Miladi,

Tarak Driss,

Ranya Ameur

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(1), P. 169 - 169

Published: Jan. 2, 2025

Aims: To evaluate the effectiveness of a dual approach involving time-restricted eating (TRE) at different times day combined with physical activity (PA) on functional capacity and metabolic health in overweight or obese women. Methods: Random allocation sixty-one participants into four groups: early plus (ETRE-PA, n = 15, 31.8 ± 10.76 years, 89.68 13.40 kg, 33.5 5.53 kg/m2), late (LTRE-PA, 30.60 7.94 94.45 15.36 34.37 7.09 only (LTRE, 27.93 9.79 88.32 10.36 32.71 5.15 kg/m2) control group (CG, 36.25 11.52 89.01 11.68 33.66 6.18 kg/m2). The intervention lasted for 12 weeks all groups. Both ETRE-PA LTRE-PA groups engaged rigorous aerobic resistance-training program. Results: Significant reductions body weight mass index were observed compared to CG LTRE post-intervention (p < 0.0005). Only exhibited significant decrease fat 0.02), low-density lipoprotein cholesterol 0.01), aspartate aminotransferase 0.002). alanine levels 0.004) 0.02) These two latter achieved higher performances 6-min walking test, bench press, 30-s squat, crunch vertical jump 0.0005 both), leg extension 0.02 both) when Conclusion: integration TRE PA leads greater improvements composition, lipid profile, performance, no differences between approaches. This strategy offers promising solution

Language: Английский

Citations

1
Independent effects of the human circadian system and sleep/eating cycles on caloric intake in adolescents vary by weight status DOI Creative Commons
David Barker, Mary A. Carskadon,

Caroline Gredvig-Ardito

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2025, Volume and Issue: 122(8)

Published: Feb. 18, 2025

Late-day eating is linked to increased obesity risk; however, whether the endogenous circadian system independently influences caloric intake and if this control differs among individuals based on weight status unknown. Here, we investigated in adolescents independent roles of behavioral sleep/wake cycle (sleep/wake, fasting/eating, rest/activity, dark/dim light, social interaction, posture, etc.) self-selected using a Forced Desynchrony protocol. Fifty-one male female across three categories (24 with healthy weight, 13 overweight, 14 obesity) completed protocol where participants lived seven 28-h cycles dim light during wake complete darkness sleep. Results suggest that each affected intake, decrease episode an increase from morning evening intake. The rhythm showed peak-to-trough difference 196 [CI 95% 164, 226] kcal per meal peak timing 296° [288°, 304°; equivalent ~17:30 these participants]. In those overweight/obesity, more calories were consumed later waking cycle, blunted amplitudes compared weight. implicate both shaping daily food Furthermore, results help explain drive for toward evening, especially at risk obesity.

Language: Английский

Citations

1
Circadian Synchrony: Sleep, Nutrition, and Physical Activity DOI Creative Commons

Kelly L. Healy,

Andrew R. Morris, Andrew C. Liu

et al.

Frontiers in Network Physiology, Journal Year: 2021, Volume and Issue: 1

Published: Oct. 12, 2021

The circadian clock in mammals regulates the sleep/wake cycle and many associated behavioral physiological processes. cellular mechanism involves a transcriptional negative feedback loop that gives rise to rhythms gene expression with an approximately 24-h periodicity. To maintain system robustness, clocks throughout body must be synchronized their functions coordinated. In mammals, master is located suprachiasmatic nucleus (SCN) of hypothalamus. SCN entrained light/dark through photic signal transduction subsequent induction core expression. turn relays time-of-day information peripheral tissues. While highly responsive cues, are more sensitive non-photic resetting cues such as nutrients, temperature, neuroendocrine hormones. For example, feeding/fasting physical activity can entrain signaling pathways regulation genes proteins. As such, timing food intake matters. ideal world, cycles cycle. However, asynchronous environmental those experienced by shift workers frequent travelers, often lead misalignment between clocks. Emerging evidence suggests resulting disruption various diseases chronic conditions cause further desynchrony accelerate disease progression. this review, we discuss how sleep, nutrition, synchronize chronomedicine may offer novel strategies for intervention.

Language: Английский

Citations

44
Amelioration of hydrolyzed guar gum on high-fat diet-induced obesity: Integrated hepatic transcriptome and metabolome DOI
Xiaodan Fu, Zhemin Liu, Rong Li

et al.

Carbohydrate Polymers, Journal Year: 2022, Volume and Issue: 297, P. 120051 - 120051

Published: Aug. 31, 2022

Language: Английский

Citations

30
Dietary Patterns under the Influence of Rotational Shift Work Schedules: A Systematic Review and Meta-Analysis DOI Creative Commons
Angela B. Clark, Alison M. Coates, Zoe E. Davidson

et al.

Advances in Nutrition, Journal Year: 2023, Volume and Issue: 14(2), P. 295 - 316

Published: Feb. 1, 2023

Workers employed in rotating shift schedules are at a higher metabolic risk compared with those regular day and fixed schedules; however, the contribution of diet is unclear. This systematic review aimed to investigate how work affect dietary energy intake patterns schedules. In addition, intraperson pattern comparisons within were investigated. Database searches conducted on MEDLINE, Cochrane, CINAHL, PSYCinfo, EMBASE, Scopus, addition manual search bibliographic references, identify articles. Two separate meta-analyses between rotational group (morning/day night shifts). Differences synthesized narratively. Thirty-one studies (n = 18,196 participants) included review, 24-hour mean data from 18 16,633 7 327 studies, respectively. The average workers was significantly than that daytime [weighted difference (WMD): 264 kJ; 95% confidence interval (CI): 70, 458 P < 0.008; I

Language: Английский

Citations

19
Effect of Circadian Rhythm Disturbance on the Human Musculoskeletal System and the Importance of Nutritional Strategies DOI Open Access
Norsham Juliana, Liyana Azmi, Nadia Mohd Effendy

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(3), P. 734 - 734

Published: Feb. 1, 2023

The circadian system in the human body responds to daily environmental changes optimise behaviour according biological clock and also influences various physiological processes. suprachiasmatic nuclei are located anterior hypothalamus of brain, they synchronise 24 h light/dark cycle. Human functions highly dependent on regulation internal clock. Skeletal muscles comprise largest collection peripheral clocks body. Both central regulate interaction between musculoskeletal energy metabolism. skeletal muscle plays a vital role lipid glucose pathogenesis osteoporosis is related an alteration rhythm. In present review, we discuss disturbance rhythm its resultant effect system. We nutritional strategies that potentially effective maintaining system's homeostasis. Active collaborations nutritionists physiologists field chronobiological chrononutrition will further clarify these interactions. This review may be necessary for successful interventions reducing morbidity mortality resulting from disturbances.

Language: Английский

Citations

17